Solid Dose Manufacturing Solutions
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Powder Rheology Accessory
4/6/2023
The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling the characterization of behaviors during storage, dispensing, processing, and end-use.
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Used 6 Station Korsch Tablet Press
6/4/2019
Used Korsch rotary tablet press, model PH106-DMS, 6 station, 40 KN compression pressure, keyed upper punch guides, 15 mm max tablet diameter, 15 mm max depth of fill, force feeder with feed hopper, rated up to 32,400 tablets/hour, with control panel, machine# 1.0062.95.
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Pharmaceutical Containment Isolators
2/9/2022
Our Rigid Stainless Steel Containment Isolators have been designed for handling potent compounds that can offer guaranteed levels of operator protection as low as 10ng/m3 (task duration). These include designs for sampling, dispensing and sub-division, mixing, milling and vessel charging, as well as containing integrated process devices such as filter dryer units, tablet press enclosures, blenders, mills and pack off systems.
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Multiparticulates For Modified Release Systems
1/12/2026
Multiparticulates enable tailored drug release with improved flexibility, dose accuracy, and patient convenience, leveraging technologies like Diffucaps® for customized profiles including immediate, delayed, extended, and pulsatile delivery.
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Pharmaceutical Preformulation Support Services
1/31/2024
Partner with Natoli Scientific during the earliest stages. Our scientific expertise with state-of-the-art analytical capabilities is ready to take any preformulation challenge.
Natoli scientific has an expertise of handling a wide range of APIs for the development of oral solids. We apply principles of ‘Quality by Design’ to define Critical Material Attributes (CMA), Critical Process Parameters (CPP), Critical Quality Attributes (CQA) and Quality Target Product Profiles (QTPP). Because we believe that understanding material and process as much as possible in the early life cycle of drug product development program is an insurance for further development path. Keeping your practices up to date with the ICHQ8 regulatory guidance issued by the US FDA. This is also a gate way for a smooth ride of product in the different stages of product development stages.
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Used Sejong Pharmaceutical Encapsulator
4/18/2023
Used Sejong Encapsulator, with change parts/tooling, 600 volts, 3 phase.
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Compounding Aseptic Containment Isolators
2/27/2026
Ensure sterile integrity and personnel safety during hazardous drug handling. Optimize workflows with advanced containment technology that adapts to complex facility and processing requirements.
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Semi-Automated Pharmaceutical Capsule Filling System
3/28/2025
The semi-automated capsule filler is part of the Explore Range, offering the potential to simplify formulation by eliminating the need for additional ‘formulation for powder filling’ steps.
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Powder Flow Properties & Characterization Services
1/31/2024
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
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Used Key International Tablet Press
10/30/2019
Used Key International single station bench top tablet press, model: SC-2. 1.5 ton compression pressure, approximately .5" max tablet diameter, .5625" max depth of fill, manual operation, serial# JI4786.