Solid Dose Manufacturing Solutions

  1. A Compact, Portable Pressure Reactor For Precise Mixing 1/8/2025

    The ROSS FDA-50 Fixed Tank Dual Shaft Mixer is a compact, portable pressure reactor designed for precise mixing, temperature, and pressure control up to 100 psi.

  2. Tablet Compression Tooling 9/10/2001

    A global leader in manufacturing, Natoli Engineering Company delivers superior tablet compression tooling. Every punch and die is produced from quarantined steel and tested for hardness and exact chemical composition by stringent quality specifications.

  3. Pharmaceutical Solid Dose Manufacturing Process Training Courses 5/16/2023

    Introducing Solid Dose Manufacturing Process Training, a comprehensive three-day course designed to equip you with the essentials of creating high-quality tablet and capsule oral solid dosage forms. Limited to 24 participants, this hands-on course ensures a more intimate learning experience tailored to each attendee's needs. Discover the techniques that will assist you in enhancing your development and scale-up operations in the pharmaceutical industry.

  4. Oral Solid Dose Formulation Assessment Services 1/31/2024

    Send a test sample of your powder to Natoli Scientific to get your formula characterized following USP <1062> Guidelines (Tablet Characterization Methods) that we have been practicing for over 25 years.

  5. Low Humidity Dispensing Enclosure for Solvents and Solids 6/24/2019

    Ultra-Low Humidity Dispensing Enclosure for Solvents and Solids designed to provide product protection during solvent and solid dispensing operations which require an ultra-low humidity contained environment. Enclosure features acrylic superstructure coated with static-dissipative coating.

  6. Used Sensum Tablet Inspection System: SPINE-073 11/1/2024

    Used Sensum tablet inspection machine, model SPINE, designed for inspection of complete surface of tablets, including engraving, speeds up to 360,000 tablets/hour for round and oblong plain tablets, 240,000/hour for engraved round tablets, 300,000 tablets/hour for oblong engraved tablets, with stainless steel product hopper and integrated operator HMI, 230 volt, 60 hertz, CE design, serial# 073, built 2017.

  7. Pharmaceutical Preformulation Support Services 1/31/2024

    Partner with Natoli Scientific during the earliest stages. Our scientific expertise with state-of-the-art analytical capabilities is ready to take any preformulation challenge.

    Natoli scientific has an expertise of handling a wide range of APIs for the development of oral solids. We apply principles of ‘Quality by Design’ to define Critical Material Attributes (CMA), Critical Process Parameters (CPP), Critical Quality Attributes (CQA) and Quality Target Product Profiles (QTPP). Because we believe that understanding material and process as much as possible in the early life cycle of drug product development program is an insurance for further development path. Keeping your practices up to date with the ICHQ8 regulatory guidance issued by the US FDA. This is also a gate way for a smooth ride of product in the different stages of product development stages.

  8. Production-Scale Pharmaceutical Filling Systems 5/14/2021

    Dec‘s philosophy is to develop customer-specific modules and equipment. Starting with agreed project scope, intensive brainstorm sessions, strong design processes and (customer) reviews, the aim is to deliver an innovative filling solution. During the concept development, risk analysis is an important tool in the decision-making process.

  9. Virus Screening And HPAPI Handling With A Continuous Process Isolator 3/11/2021

    The Analytical Process Isolator™ or A.P.I. is a continuous process isolator to vented enclosure system that allows for ISO 5 clean processing and intake or outtake through a negative pressure vented cabinet.

  10. Pharmaceutical Sterile Compounding Isolator: MicroSphere 6/24/2019

    The MicroSphere is a clean, cost-effective C.A.I for sterile compounding, that is USP <797> compliant.