Solid Dose Manufacturing Solutions

  1. Powder Flow Properties & Characterization Services 1/31/2024

    Basic Powder Flow Characterization [USP <1174>]:

    A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.

    Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.

    When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.

  2. Conveying Of Granules, Flakes And Large Sized Particles: Transbatch 8/13/2020

    The patented Transbatch system relies on modern technology to safely convey and dose granules and other solids under critical installation conditions in terms of both transfer length and height.

  3. Replace Your Worn Segmented Turret Today 10/9/2025

    Now you can upgrade to Natoli’s premium segmented turret for your Fette Press! Natoli Engineering has 20 years’ experience in manufacturing segments, backed by ongoing investments in advanced R&D, CNC process automation, and precision finishing which meets often surpasses the OEM - Our quality is in the detail. The Fette patent is now expired, and Natoli is ready to deliver unmatched quality and performance.

  4. Pharmaceutical Glove Isolator Tester: FZ-GTS 4.0 9/24/2024

    Maximize glove testing efficiency

    Improve your glove testing with the FZ-GTS 4.0. This innovative system delivers unmatched flexibility to adapt to your testing needs, seamlessly integrating with existing workflows for increased efficiency.

  5. Used Vector Granulator: CF360E 6/18/2019

    One (1) used Vectro granulator, mdoel CF360EX, stainless steel construction, 3-5 kg capacity, xp design with controls, 220 volt, serial# CF-110, new 1982.

  6. OSD Pharmaceutical Tablet Manufacturing Services For Clinical Trials 1/31/2024

    Natoli Scientific offers manufacturing services of oral solids at a pilot scale and drug products for clinical trials.

    We also offer full-scale commercial manufacturing service till you are ready with your own manufacturing facility to avoid delay in the commercial launch.

    Team Natoli understands the complexity of the tablet manufacturing process over more than half a century. We are ready to shoulder every step of the tablet manufacturing chain from blending to granulation, to milling, to compression, to coating. Our manufacturing capabilities are backed up by our expert scientific team, who are ready to offer guidance in product development, technical transfers, and scale-ups.

  7. Build Your Solution: Not Every Molecule Follows A Manual 2/26/2026

    A flexible, data‑driven development approach assembles tailored scientific strategies around each molecule, reducing risk, improving manufacturability, and enabling scalable formulation solutions.

  8. Used Glatt GPCG2 LabSystem Fluid Bed Dryer 10/1/2025

    Used Glatt GPCG2 LabSystem Fluid Bed Dryer, 200-460V, 50/60Hz, 3 PH, serial# 79589, built 2013.

  9. Used MG2 Planeta 100 Pharmaceutical Capsule Filling System 4/28/2022

    Used MG2 continuous motion capsule filler, model Planeta100, nominally rated up to 100,000 capsules/hour, currently set up for microdose capsules, multinet weight control unit less scale system, 460 volt, serial# 4697, built 2014.

  10. Unused 300 Liter Fluid Air Pharmaceutical Fluid Bed Dryer 7/2/2025

    Unused Fluid Air 300 liter fluid bed dryer, model 300, 316 stainless steel contact parts, 304 non product contact, includes tower, filter system, explosion suppression system, product bowl with automatic side discharge, hydraulic bowl lifting system, spray nozzles (for possible conversion to top spray granulation), HMI and machine controls, valves, and other associated parts, serial# 10440, built 2014.