Solid Dose Manufacturing Solutions

  1. Pharmaceutical Encapsulation Change Parts And Kits Catalog 4/17/2019

    Natoli Engineering Company, through its Carlisle Precision Encapsulation Parts subsidiary, manufactures premium change and spare parts for many brands of encapsulation machines.

  2. Used Bausch & Stroebel Powder Filling System: SP-100 3/26/2021

    Bausch + Strobel SP-100 Powder filling Machine with control cabinet, stainless steel construction, with filler funnels and auger, serial# 51181, built 1998.

  3. Solid Form Services

    We have defined work flows to assess and select solid forms in a cost and time efficient manner that meets the needs of each individual program.

  4. Used 19 mm Baker Perkins Twin Screw Extruder 7/19/2022

    Used 19 MM APV Baker Perkins twin screw co rotating extruder, model MP-19-TC, 19 mm diameter screws, 40:1 l/d, electrically heated, water cooled barrel, split barrel design, 2 kw dc motor, 500 rpm screw spped, with Ktron main feeder, (2) Brabender auxiliary feeders, (3) Zenith melt pumps, FTS chiller, external control panel, with associated screws, screw elements, control panel, 220 volt, CE rated, APV serial# NEF990028-701/1, Baker Perkins serial# TS99535, project# 99TS196, built 1999.

  5. Used IMA Pressima Pharmaceutical Tablet Press 6/3/2021

    Used IMA Zanasi 6 F Capsule Filler, rated up to 6000 capsules/hour, no change parts, capable of producing 00-5 size capsules, with controls and Siemens PLC, 230 volt, 3 phase, serial# 35071, built 2006.

  6. Oral Solid Dose Formulation Troubleshooting Support Services 1/31/2024

    Natoli organization is a reputed leader with more than a half century experience in the tablet manufacturing technology.

    We understand tablets better. We are here for serving your needs to overcome challenges associated with commercial manufacturing of solid dosage forms across the globe (North America, Europe, Asia).

    Our Natoli scientific team uses holistic approach to understand and solve important tableting problems like capping, lamination, picking, and sticking. We integrate scientific information gathered at material, process, and instrument level to understanding and decode root causes of these common tableting issues.

  7. Used Stokes 45 Station Pharmaceutical Tablet Press 10/1/2025

    Used Stokes BB2 Tablet Press, 45 station, B-tooled, dual sided, 4 ton compression, feed frames with hoppers, 7/16" max tablet diameter, 11/16" max depth of fill, 4200 tablets per minute max speed.

  8. Used Korsch XL 400 2-Layer Tablet Press, 35/29 Station 8/3/2021

    Used Korsch XL 400 2-Layer rotary tablet press. 35 station with B turret, 29 station with D turret. Serial# K1500036, built 2001.

  9. LAF Downflow Booths For Weighing And Sampling Powders 11/25/2024

    The LAF Downflow Booth provides product and personnel protection during the weighing or sampling of powdered substances through precise air circulation.

  10. Compaction Simulation / Emulation 7/30/2024

    Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.