Solid Dose Manufacturing Solutions

31. Precision CT Scan Services: Uncovering Flaws For Flawless Tablets 10/9/2025

    At Natoli, we know that quality is paramount. Our cutting‐edge Precision CT Scan Service is designed to detect even the subtlest imperfections in tablets, ensuring you achieve the highest standards of quality every time.

32. Dust-Free Bulk Powder Transfer 8/12/2015

    Dust-free bulk powder transfer from cardboard boxes, sacks or drums by means of a feed hopper with weighing frame. Positive raw material identification and registration by means of barcode scanners.

33. EZ Level Feeder Table Leveling System 10/9/2025

    Stop wasting time on frustrating, trial-and-error methods to level your tablet press feeder platform. "Close enough" isn't good enough—especially when it leads to excess formulation loss or costly equipment damage. With the Natoli EZ Level™ Feeder Base Leveling System, you can achieve fast, accurate, and repeatable results—every time.

34. Powder Flow Properties & Characterization Services 1/31/2024

    Basic Powder Flow Characterization [USP <1174>]:

    A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.

    Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.

    When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.

35. Compaction Simulation / Emulation 7/30/2024

    Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.

36. Pharmaceutical Filling Lines With High Containment 9/11/2020

    Dec offers pharmaceutical filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.

37. From Formulation To Global Supply: Mastering Oral Solid Development 4/9/2026

    A global, integrated approach to oral solid dosage development combines formulation science, advanced delivery, and scalable manufacturing to support efficient clinical progress and reliable supply.

38. Used ACG Pam AFT LAB Pharmaceutical Capsule Filling Equipment 10/3/2023

    Used ACG-Pam Capsule Filler, Model AFT LAB.

39. Integrated Turn-Key Solutions For Aseptic Filling And Containment 6/29/2026

    See how aseptic processing, containment, transfer, and integrity testing can be combined into flexible, regulation-ready workflows that improve operator safety and protect product quality.

40. Morpho Capabilities Deck 10/7/2026

    Sterile fill and finish and oral solid dosage manufacturing, supported by Italian and US sites, development labs, and inspection records, carry complex products from formulation to commercial supply.