Solid Dose Manufacturing Solutions

  1. Replace Your Worn Segmented Turret Today 10/9/2025

    Now you can upgrade to Natoli’s premium segmented turret for your Fette Press! Natoli Engineering has 20 years’ experience in manufacturing segments, backed by ongoing investments in advanced R&D, CNC process automation, and precision finishing which meets often surpasses the OEM - Our quality is in the detail. The Fette patent is now expired, and Natoli is ready to deliver unmatched quality and performance.

  2. Powder Discharging Systems For Non-Potent To High Potent Active Ingredients 8/7/2020

    The big bag emptying stations of Dec are based on a modular design. This allows to be ideally equipped with systems for each product’s characteristics with corresponding docking systems for non-potent to highly active powders. Depending on the product flow, there is a range of discharge devices or lump breakers available. With the use of load cells, it is possible to dose accurately into the receptacle.

  3. Used Elizabeth Hata Pharmaceutical 10 Station Tablet Press 10/3/2023

    Used Elizabeth Hata R&D tablet press, model EP200, B/D tooled with 10 station turret, 5 stations each B and D, 16 mm B, 22 mm D max tablet diameter, 17 mm B, 18 mm D max depth of fill, rated up to 6000 tablets/hour, with feed hoppers and feed frames, Machine #81, built 2011.

  4. Pharmaceutical Filling Lines With High Containment 9/11/2020

    Dec offers pharmaceutical filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.

  5. Pharmaceutical Encapsulation Change Parts And Kits Catalog 4/17/2019

    Natoli Engineering Company, through its Carlisle Precision Encapsulation Parts subsidiary, manufactures premium change and spare parts for many brands of encapsulation machines.

  6. From Formulation To Global Supply: Mastering Oral Solid Development 4/9/2026

    A global, integrated approach to oral solid dosage development combines formulation science, advanced delivery, and scalable manufacturing to support efficient clinical progress and reliable supply.

  7. Pharmaceutical Bench-Top Filling & Closing Machines: GENiSYS® Lab 12/27/2019

    AST’s line of table-top machines, GENiSYS® Lab, are ideal systems for drug product development and cGMP production applications. Each system is designed to automate the critical aseptic operations for vial, syringe and cartridge processing to reduce contamination risk and product variability. These table-top systems are engineered to have complete compatibility with cleanroom environments, including Laminar Air Flow Hoods, Bio-Safety Cabinets and aseptic isolators.

  8. Compaction Simulation / Emulation 7/30/2024

    Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.

  9. NP-400 Medium-output Single Footprint Rotary Press 7/16/2015

    Our NP-400 is a 24/7 workhorse that features built in controls and off-the-shelf electronics. A self-lubricated turret and upper and lower cams reduce maintenance costs and provide longer operation time. The NP-400’s compact design is ideal for tablet manufacturers who need a reliable, efficient press to make up to 3,000 tablets per minute.

  10. Micronizing And Milling Isolators For Drug Manufacturing 8/6/2020

    Over many years, Dec has acquired recognized expertise in designing and supplying an extensive range of isolators enclosing a mill or a MC DecJet® spiral jet mill for either individual or combined operation.