Solid Dose Manufacturing Solutions
-
A User-Friendly Solution For Fill-Finish Professionals
1/31/2024
When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
-
Containment: Offloading
5/2/2011
Containment solutions for the contained offloading of Aurora Filters.
-
Used Killian 16 Station T100 Tablet Press
2/23/2023
Used Kilian rotary tablet press, model T100, 16 station, B/D IPT turret, with (8) B tooled, 16 mm diameter, 16 mm depth of fill and (8) D tooled, 25 mm diameter, 16 mm depth of fill stations in single turret, with additional 9 station IPT B toolded turrent, 42 Kn pre-compression, 65 Kn main compression, keyed upper punch guides, singled sided with force feeder, commission# 706849, built 2002.
-
High-Containment Solutions For HPAPI Handling
6/15/2026
Handling highly potent active pharmaceutical ingredients calls for containment systems that protect operators while maintaining strict OEL thresholds below 0.1 μg/M3 throughout every transfer step.
-
API Manufacturing And Material Handling Equipment
5/25/2021
Active pharmaceutical ingredient (API) manufacturing requires powder handling in a GMP and contained manner. Similar to chemical manufacturing, operations like charging powders into a chemical reactor, emptying a centrifuge or charging and discharging a dryer are standard processes.
-
Used GlobeParma Pharmaceutical Tablet Deduster System: Model GPTD-100
4/28/2025
Used Globepharma tablet deduster, model GPTD-100, 115 volt, serial# 011934876, built 2019.
-
Used Manesty Tablet Press, Model Unipress Diamond
12/6/2019
Used BWI Manesty Unipress Diamond rotary table press, 27 station, keyed upper punch guides, 6.5 ton main compression, 1 ton pre compression, B tooled, 16 mm max tablet diameter, 18 mm max depth of fill, single side with force feeder with feed hopper, rated up to 196,200 tablets/hour, serial# UN248JA.
-
Tablet Compression Tooling
9/10/2001
A global leader in manufacturing, Natoli Engineering Company delivers superior tablet compression tooling. Every punch and die is produced from quarantined steel and tested for hardness and exact chemical composition by stringent quality specifications.
-
Used GlobePharma Single Station Pharmaceutical Tablet Press
2/15/2024
Used GlobePharma Single Station Tablet Press.
-
Used Kikusui 36 Station Pharmaceutical Tablet Press: AQUARIUS G-J
9/30/2025
Used Kikusui tablet in tablet press, model Aquarius G-J/DC, 36 station, keyed upper punch guides, B tooled, 100 kN pre-compression, 100 kN main compression, 16mm max tablet diameter, 18mm max depth of fill, rated up to 259,200 tablets/hour, with DC module for core feeder, 4-15mm core depth adjustment, with integrated primary and secondary powder feed hoppers, and core feed hopper, project# 1-6302, built 2009.