Tablet Production White Papers & Case Studies

  1. Protecting Dry Pharmaceutical Product From Moisture Permeation
    12/27/2018

    How non-destructive headspace analysis information can be critical for QC groups performing stability studies, or for packaging development groups responsible for choosing the optimal primary packaging configuration.

  2. Lyo Chamber Moisture Mapping
    12/27/2018

    Rapid non-destructive headspace moisture analysis from LIGHTHOUSE enables fast moisture determination of statistical numbers of lyo samples.

  3. Using Non-Destructive Headspace Analysis To Address Customer Complaint
    12/27/2018

    In cases where oxidation of the formulation causes discoloration and eventual degradation of the product, non-destructive headspace analysis tests can give deep insight into the root cause. Since the samples are not destroyed by the headspace analysis, further testing can be done to accurately correlate headspace conditions with other product characteristics.

  4. Redefining Fast Melt For Pharma With 3D Printing
    7/31/2018

    Adults and children alike often struggle with compliance and acceptance of medication regimens due to the sizes and shape of prescribed tablets. One pharmaceutical manufacturer sought to create a convenient, easy-to-swallow dosage form by taking an alternative approach: three-dimensional printing (3DP). This white paper outlines their approach to creating an FDA validated manufacturing process for rapidly disintegrating dosage forms.

  5. 5 Steps To Increase Energy-Efficient Mixing
    3/1/2018

    Mixer testing simulation trials are needed to confirm the suitability of a specific mixing strategy. This white paper explores five ways to increase energy efficiency in new and existing mixing processes.

  6. Efficiencies In Powder Dispersion For Manufacturers
    3/1/2018

    Uniformly dispersing powders into a liquid batch in a practical amount of time is a common problem for F&B manufacturers. This white paper explores five tips for dispersing powders more efficiently.

  7. How To Optimize Solid-Liquid Mixing
    3/1/2018

    This paper provides practical information on the efficient use of specialty mixing equipment for the preparation of low, medium and high viscosity solid-liquid mixtures under low and high shear conditions.

  8. Development Of Biopharmaceuticals Requiring Lyophilized Formulations
    1/18/2018

    Development of a drug formulation and lyophilization (freeze drying) process begins with laboratory experiments followed by scale up to larger lyophilizers. 

  9. Revolutionizing Allergy Therapy
    8/11/2017

    ALK-Abelló is a global research-driven pharmaceutical company that focuses on the prevention, diagnosis and treatment of allergies. Before ALK-Abelló partnered with Catalent, all marketed allergen immunotherapies were delivered by injection, resulting in a limited patient population and reduced patient adherence. Catalent worked with the client to apply Zydis Fast Dissolve Technology to their therapy. The overall result was a marked improvement in patient tolerability, preference and compliance.

  10. The Importance Of Land Width On Pharmaceutical Tablet Design
    6/10/2016

    Tablet land is beneficial to add strength and durability to the punch tip. But, this hand land may be perceived as making it more difficult to coat the tablet.