FEATURED ARTICLES

• Pharmaceutical Liquid Filling Systems — A Succinct Comparison And Selection Guide

  View an attributes comparison of the primary strengths and weaknesses of the various filling systems based on the properties of the fill media, availability of additional functionality, filling tolerance, capital cost, and overall benefits and limitations.

• The 4 Ways AI Implementation Is Changing The Future Of Precision Medicine
• Model-Based Control In Continuous Biomanufacturing
• Two Emerging Fields Propelling AI In Precision Medicine
• Juno v. Kite: Implications For Functionally Claimed Biologics

WHITE PAPERS & CASE STUDIES

• Agglomerate-Free Dispersion For Hand Sanitizers

  Obtaining an agglomerate-free dispersion is essential to ensure a clear, bright gel after neutralization but low density powders such as Carbopol can be difficult to incorporate into liquids with a conventional agitator. The high shear mixing of a Silverson mixer ensures rapid incorporation and dispersion of powders to form an agglomerate-free solution, with minimized aeration.

• Line Of Sight - Enabling Lyophilization Scale-Up From Formulation To Full Commercial Production

  Line of Sight suite of freeze-drying equipment with scalable lyophilization technologies and process analytical technology (PAT) tools have been developed to provide the tools for a more successful scale-up of a lyophilization process from formulation through to full commercial production. This ensures superior product quality and uniformity and creates a data rich environment across all sizes of freeze-drying systems.

• Enabling Lyophilization Scale-Up From Formulation To Full Commercial Production

  Biologic drugs have shown great promise in curing many life changing diseases, even some that were once thought incurable. However, due to the sensitive nature of  biological material it requires specialized development and manufacturing processes. Stabilization by lyophilization is attractive to retain the product’s biological activity, structural integrity and homogenous quality, all of which are crucial to the success of the product. This white paper describes the challenges associated with lyophilization of biologic drug products.