This article is the first in a three-part series exploring the need and means to achieve improvement in aseptic processing of sterile biopharmaceutical products. Part 1 will present the current state and opportunity for improvement using innovative technology. Part 2 will further discuss some of the changes in strategy that might be needed for and result from the use and improvement of technology. Part 3 will present the impact of technology changes.
A collaborative study involving Cardinal Health, Inc. and Air Dispersions Ltd. has been carried out to further the understanding of the extrusion process and its impact upon the quality of Blow/Fill/Seal product.
Aseptic blow-fill-seal systems for packaging pharmaceutical liquids incorporate materials and process that provide critical advantages for sustainable initiatives.
A collaborative study with a new customer with the objective of taking an existing, smaller preclinical E. coli process previously performed in stainless steel vessels and scaling it up quickly using the Thermo Scientific™ HyPerforma™ 300 L Single-Use Fermentor (S.U.F.)
In the processing of ophthalmic solutions, high-shear mixers are utilized for dissolving salts as well as dispersing viscosity enhancers, antioxidants and other additives.
A majority of pharmaceutical gels are shear-thinning semisolids prepared by dispersing hydrophilic polymers into an aqueous vehicle. Proper mixing requires a good balance between agitation and shear.
Dry blending is an indispensable operation in the manufacture of multivitamins, sports supplements, herbal extracts, meal-replacements, green food powders and other nutraceutical products.
Bosch's MLD 3000 machine series is recognized for its performance, precision and pharmaceutical safety. The MLD 3000 machine series is suitable for medium and high production rates. The series fulfills the desire of many manufacturers to have a truly customized solution to fit their specific needs.
KOMAL "ED" series of Electrodeionization unit employs EDI technology to produce high purity water. EDI process systems replace conventional Dl mixed bed resins unit to produce deionized water. KOMAL EDI does not require shutdowns to regenerate the resins with chemicals or replacing resins. Consistent high purity Ultrapure water having resistivity of 12-15 Mohm .cm can be produced.
KOMAL manufactures a Corona Discharge Ozone Generator and Ozone application Engineering Including dissolution column, air preparation unit and Ozone destruction. 'OZ1 series of Ozonator Generator operate exclusively on oxygen feed gas, Eliminating the need of Air preparation unit. For the smaller requirement of ozone 'OZ' Series Ozone Generator is very efficient, reliable and very cost - effective.
Water is one of the most abundant natural compounds. It is also one of the most contaminated one. A number of minerals readily dissolve in to water. They have to be removed from the raw water before it can be used for any industries application.
KOMAL industries is a Water Treatment Plant manufacturing company dedicated to offer to our customers the finest commercial, industrial and medical Reverse Osmosis system. We are committed to provide the most innovative, technologically advanced and high quality system. Our knowledge and experience enable us to manufacture most of our parts in-house to ensure system reliability. Our meticulous quality assurance program ensures system reliability and a product that you can depend on.
Komal manufactures complete system to meet very special application for the Research lab and electronic industries. Water produced will meet the standards like CAP, ASTM, USP, NSST etc. Standard units having flowrate of 5/10/30 lit/hr. is readily available. Units are microprocessor based controlled with replaceable cartridges.
Once the PW is stored in a tank, it now needs to be distributed to each and every point of use in the factory without recontamination.
After the purification of PW or HPW, engineering of the customer-specific storage and distribution system takes place, so product water can be delivered to each point of use in the sterile distribution system without recontamination. Here to we consider the customer's specific conditions and produce an individually engineered design.
