FEATURED ARTICLES

• Pharma Process Validation: Initial Conclusions Are Often Deceptive

  As a pharmaceutical consultant, this author has observed many pharma process validation outcomes. In this article, he provides insights into two recent process validation problems that could have been avoided with an enhanced developmental approach and a greater understanding of the impact of CMAs and CPPs.

• A CTO’s Journey Into Continuous Biomanufacturing
• The Environmental Impact Of Biopharma Continuous Manufacturing: Part II
• The Process Map To Ensure Biopharma Raw Materials Supply
• Liposome Vs. Lipid Nanoparticle: What's The Difference?

WHITE PAPERS & CASE STUDIES

• High Concentration Monoclonal Antibody Drugs Manufacturing Challenges

  A review of high-conentration mAb manufacturing challenges including viscosity, aggregation, instability, and the effect of excipients on formulation, filtration, and fill and finish and bioavailability.

• Agglomerate-Free Dispersion For Hand Sanitizers

  Obtaining an agglomerate-free dispersion is essential to ensure a clear, bright gel after neutralization but low density powders such as Carbopol can be difficult to incorporate into liquids with a conventional agitator. The high shear mixing of a Silverson mixer ensures rapid incorporation and dispersion of powders to form an agglomerate-free solution, with minimized aeration.