FEATURED ARTICLES

• Common Challenges And Solutions Of Equipment Ownership And Use

  There are many factors to consider when tasked with acquiring the equipment needed to run a pharmaceutical facility. Being aware of every upfront costs is a must when determining optimal equipment ownership. See how state-of-the-art used equipment can be a great strategy for cost savings for businesses.

• Freeze-Drying COVID-19 Diagnostics: Formulation & Process Development And Lyophilizer Selection
• Equipment Capability Of Freeze-Dryers And Its Relevance To The Graphical Design Space For Primary Drying
• Freeze Drying Of Vaccines – Challenges And Concepts In Formulation And Process Development
• Bridging The Divide - Streamline The Process Development & Tech Transfer Process

WHITE PAPERS & CASE STUDIES

• Agglomerate-Free Dispersion For Hand Sanitizers

  One of the key steps in the manufacturing process of hand sanitizersis preparation of the gel. Obtaining an agglomerate-free dispersion is essential to ensure a clear, bright gel after neutralization but low density powders such as Carbopol can be difficult to incorporate into liquids with a conventional agitator, and this can lead to dusting problems and aeration. The high shear mixing of a Silverson mixer ensures rapid incorporation and dispersion of powders to form an agglomerate-free solution, with minimized aeration.

• Line Of Sight - Enabling Lyophilization Scale-Up From Formulation To Full Commercial Production

  Line of Sight suite of freeze-drying equipment with scalable lyophilization technologies and process analytical technology (PAT) tools have been developed to provide the tools for a more successful scale-up of a lyophilization process from formulation through to full commercial production. This ensures superior product quality and uniformity and creates a data rich environment across all sizes of freeze-drying systems.

• Enabling Lyophilization Scale-Up From Formulation To Full Commercial Production

  Biologic drugs have shown great promise in curing many life changing diseases, even some that were once thought incurable. However, due to the sensitive nature of  biological material it requires specialized development and manufacturing processes. Stabilization by lyophilization is attractive to retain the product’s biological activity, structural integrity and homogenous quality, all of which are crucial to the success of the product. This white paper describes the challenges associated with lyophilization of biologic drug products.

• Venting Fume Hood Base Cabinets — A Better Way

  Frequently, companies have used fume hood exhaust to ventilate hood base cabinets. There is both the need for this practice and the designs for them are frequently not well thought-out. 

• The Keys To Superior Containment In Compounding Applications

  This paper reviews why very bad things happen when either quantity or purity of Highly Potent Active Pharmaceuticals is not properly maintained during the compounding process.