FEATURED ARTICLES
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![big data personal information safety technology-iStock-929002810]( "9 Pitfalls To Avoid In Data Integrity in Pharmaceutical and Device Development & Operations")
9 Pitfalls To Avoid In Data Integrity in Pharmaceutical and Device Development & OperationsThe first article in this series examined 5 common misconceptions in data integrity (DI). In this article, the author now shares 9 example areas where he has seen significant DI implementation problems in pharmaceutical and medical device companies.
- How To Find & Manage Biotech Consultants Effectively
- What’s The Role Of Interim Consultants In The Life Sciences & How Do We Use Them Effectively?
- Best Practices For Raw Material Supplier Change Notifications: New BioPhorum Guidance
- An Analysis Of ICH Draft Guidance Q13: Continuous Manufacturing Of Drug Substance And Drug Products
WHITE PAPERS & CASE STUDIES
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![Medicine capsule manufacturing machine.jpg]( "Product Development For An Oral Solid Dosage Using Continuous Manufacturing")
Product Development For An Oral Solid Dosage Using Continuous ManufacturingA thorough evaluation using several small-scale studies should be completed to help determine whether continuous or batch manufacturing is the best fit for your product.
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![magnifying glass w pills 450x300]( "Pediatric Dosage Form Considerations For Highly Potent Compounds")
Pediatric Dosage Form Considerations For Highly Potent CompoundsThe development of pediatric medicine poses numerous challenges to pharmaceutical formulators, particularly products intended for infants and very young children. This white paper describes special considerations for selecting appropriate pediatric dosage forms and the benefits of choosing mini-tablets (e.g., orodispensible) for pediatric formulation, particularly for highly potent compounds.
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![Capsules]( "Extrusion- Spheronization, Engineered For Today’s Controlled Release Forms")
Extrusion- Spheronization, Engineered For Today’s Controlled Release FormsSynchronizing and controlling API delivery, extrusion-spheronization offers pharmaceutical companies a robust technique to manufacture today’s most complex therapeutics. With the right capabilities, this well-understood process stands ready to help lead the development and manufacturing of both today’s and tomorrow’s complex OSD therapeutics.
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![blue and white pills 450x300]( "In-Situ, Non-Destructive Surface Area Measurement For The Optimal Application Of Lyophilization")
In-Situ, Non-Destructive Surface Area Measurement For The Optimal Application Of LyophilizationA key focus of this paper is the relevant measurement of surface area, with experimental data demonstrating the performance and value of novel instrumentation for in-situ characterization.
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![Flow Sciences]( "Manufacturer Finds Solution For Transporting HPAPI Product with Containment")
Manufacturer Finds Solution For Transporting HPAPI Product with ContainmentA client was in need of a containment enclosure for an analytical weighing and solution-preparation operation involving Highly Potent Active Pharmaceutical Ingredients (HPAPI) in powder form. Their goal was to transfer product from an enclosure to another enclosure. read how Flow Sciences used a recently developed containment device and augmented to fit the specific needs of the client.
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![Venting Fume Hood]( "Venting Fume Hood Base Cabinets — A Better Way")
Venting Fume Hood Base Cabinets — A Better WayFrequently, companies have used fume hood exhaust to ventilate hood base cabinets. There is both the need for this practice and the designs for them are frequently not well thought-out.
PRODUCTS & SERVICES
Used Fette 3090i WiP rotary tablet press with containment, 75 station segmented turret, 100 Kn pre-compression, 100 Kn main compression pressure, 11, 18, 25 mm max tablet diameter depending on segment spacing, 22 mm max depth of fill, keyed upper and lower punch guides, double sided with force feeders, rated 528,000 -1,080,000 tablets/hour production speeds depending on tablet diameter, 3 phase, 50-60 hertz, 400 volt, mounted in WIP(Wash In Place) containment isolator, with Two (2) Pharma Technology Combi 1000i WIP units with deduster and Lock MET30+ metal detectors, 230 volt, mounted in WIP(Wash In Place) containment isolators, with, Fette Checkmaster 4 tablet testing unit, type CM4.1, 100-240 volt, serial# 02100105, operator interface, WIP(Wash In Place) control skid and control panel, Pharma Technology serial#'s 0504751, 0504752, Lock serial# 25359-1, 25358-1, Fette serial# 280053, system built in 2005.
Used Korsch XL 400 2-Layer rotary tablet press. 35 station with B turret, 29 station with D turret. Serial# K1500036, built 2001.
Twin screw feeders can be used for free flowing powders and fine granulates but they are ideal for feeding difficult materials such as pigments, sticky, bridging or flooding powders, fiber and fiberglass.
Single screw feeders are ideal for feeding free flowing bulk materials such as pellets and powders.
No two process applications are the same, and Coperion K-Tron offers the widest range of feeding solutions in the industry. From screw feeders to vibratory feeders, bulk solids pumps, weigh belts, liquid feeders and flow meters, all feeders are offered in a variety of configurations, which can be combined to create an optimal solution for any application.
Used Manesty rotary tablet press, model Mark IV, 49 station D tooled, keyed upper punch guides, 1 ton pre compression, 10 ton main compression, 1" max tablet diameter, 13/16" max depth of fill, with change parts for single layer and bi layer tablets, rated 392,196 tablet/hour single layer, 196,098 tablets/hour bi layer, refurbished by IPR in 2014, serial# TPAC2014-072.
Used Kikusui Tablet Press rebuilt by Natoli, Model Gemini 67, 55 station turret, 460 volt, rebuilt in 2008, serial# 1-5577, with (2) Kramer deduster / Lock metal check units.
Factory Demo IMA Prexima 300 rotary tablet press, 33 station, TSM B tooled, 100kn pre compression and main compression, with force feeder, 16 mm max tablet diameter, with 8, 12, 16 and 19 mm fill cams, nominally rated up to 237,600 tph with HMI. Please see attached IMA Prexima 300 tablet press, serial#KC1034 quotation with applicable IMA terms and conditions.