Avoid inconsistent and even dangerous dosages being tableted by monitoring segregation during the process.
This white paper explores five ways to increase energy efficiency in new and existing mixing processes.
Natoli Engineering Company recently completed a successful Factory Acceptance Test (FAT) with a top-tier cosmetics company.
When scaling a new drug formulation from the development side of R&D into manufacturing, there is often a reality check with respect to process scale- up and performance of the formulation at production levels. By Chuck Kettler, Director, Natoli Scientific of Natoli Engineering Company, Inc.
Almac has developed a flexible paediatric dosage form consisting of minitablets filled into stickpacks using a robust manufacturing and filling process suitable for routine commercial manufacture.
Providing support in all aspects of the tablet compression process should be expected from your tooling and tablet press partner.
Clinical studies on solid dose products may require a placebo. The placebo, in the case of a tablet, should possess the same shape and color compared to the active product.
Natoli Engineering now offers AIM™ Data Acquisition & Analytical Software for the Natoli NP-RD10A research and development tablet press. The combination of AIM™ Software and this R&D tablet press enables the researcher to evaluate formulation properties and identify potential tableting issues—including capping, lamination, sticking/picking, and tablet robustness—during the tablet development process. Plus, the software can optimize tablet tensile strength and lubrication for successful large-scale manufacturing production.
For the gentle handling of tablets, Hanningfield offer a specifically designed IBC. The design uses a shallow body angle and a flexible-vane outlet valve to minimise risk of tablet breakage and damage. The IBC can be supplied with an outlet chute for transferring the tablets into a coater.
Hanningfield’s Drum Tumblers are designed for the gentle tumbling of drums to create uniform batches. The tumblers are suitable for almost any drum size (e.g. 50, 100, 200 litres), with a typical maximum SWL of 200kgs and a variable RPM.
Each service visit will include the following:
Natoli’s line of efficient tablet presses combine remarkable tablet production, automation and dependability.
Pentapack advanced unit dose pharmaceutical blister packaging systems offer the unique capability to package both solid and liquid dose medications with one machine. Medications are clearly identified with bar code labeling software and high resolution label printing.
Using a cyclone on the extraction line facilitates interception of this powder before it ever leaves the process room, enabling high integrity batch reconciliation and minimizing filter replacement.
The 9505 stainless steel pneumatic conveyor is designed for the transfer of empty 00-5 sized capsules. Capsules are emptied into a collection container and dispensed at an adjustable rate into a capsule-filling machine. This unique conveyor uses air power to push the capsules through rigid sanitary piping into a hopper above the capsule-filling machine without damaging the capsules. The Nilfisk product conveying process takes place in perfect hygienic conditions, respecting both the environment and the operators’ health.
