Engineering is a process to develop a design to solve a problem. In the world of containment engineering, careful premeditation is important to the completion of a successful engineering project.
Manufacturing tablets to a uniform hardness, weight, and thickness requires tablet press punches of consistent length. This paper describes how to understand punch length, how to measure it correctly, and how wear affects length and tablet consistency. It also addresses the importance of specifying cup-depth tolerances.
Frequently, customers have used fume hood exhaust to ventilate hood base cabinets. There is both the need for this practice and the designs for them are frequently not well thought-out. Alternate rationales and approaches to this ventilation method are reviewed with clear-cut recommendations in this paper.
This paper reviews why very bad things happen when either quantity or purity of Highly Potent Active Pharmaceuticals is not properly maintained during the compounding process. Additionally, when highly potent active pharma ingredients are not effectively contained, workers may be adversely affected.
When executed properly, HME advances poorly soluble compounds in the development pipeline, without adding delays, cost, or significant post-processing activities, and can scale to commercial manufacturing.
Understanding and being able to control granulation is essential to the production of high quality pharmaceuticals. Fluid bed granulation and melt granulation can be tightly regulated to produce uniform material with a specified particle size therefore affording superior process reproducibility and better process control than many other granulation techniques.
The enhanced precision used in 3D printing can drive efficiencies in early drug development by allowing more flexibility with dosage size and strengths, leading to a more effective use of costly resources.
Endress+Hauser offers continuous level measurement and point level detection in liquids and bulk solids.
The JetVent system allows for easy and confident handling of expensive and dangerous powders.
Fast Powder Mixing And Complete Protection Of Powder Properties
The efficient mixing of media and buffer powders into liquids is a crucial step in profitable pharmaceutical and biopharmaceutical manufacturing.
In the pharmaceutical industry, granulation is used to create bonds between particles as part of the oral solid dosage manufacturing process. ILC Dover supplies a family of products that support contained granulator operation and features validated containment technology, clear film, and the ability to retrofit to existing equipment design.
Milling is a common operation throughout the pharmaceutical manufacturing process. Sizing of powders is a dusty operation and with more potent powders being processed, the need for containing this operation becomes even more critical from safety and cross contamination avoidance purposes.
Tablet coating is a common operation throughout the pharmaceutical manufacturing industry. ILC Dover supplies a family of products that support contained Tablet Coating operation.
Tablet compression is a common operation throughout the pharmaceutical manufacturing industry. ILC Dover supplies a family of products that support contained Tablet Compression operations.
Krämer dedusters ensure a smooth operation daily at the sites of hundreds of pharmaceutical companies, ranging from multinationals to small local manufacturers of tablets and capsules. The company's E80-N tablet deduster is Ideal for production of middle-sized charges and research applications
