“How long should a set of tools last?” is one of the most common questions asked of tooling vendors. The answer is dependent on many factors.
Natoli Engineering Company recently completed a successful Factory Acceptance Test (FAT) with a top-tier cosmetics company.
When scaling a new drug formulation from the development side of R&D into manufacturing, there is often a reality check with respect to process scale- up and performance of the formulation at production levels. By Chuck Kettler, Director, Natoli Scientific of Natoli Engineering Company, Inc.
Almac has developed a flexible paediatric dosage form consisting of minitablets filled into stickpacks using a robust manufacturing and filling process suitable for routine commercial manufacture.
Compression tooling and tablet press manufacturers are faced with ongoing challenges in the tablet manufacturing environments. Providing support in all aspects of the tablet compression process should be expected from your tooling and tablet press partner. These services should include: press operator training, maintenance/calibration services, quick delivery of replacement parts, tooling, tablet design and powder formulation support.
Clinical studies on solid dose products may require a placebo. The placebo, in the case of a tablet, should possess the same shape and color compared to the active product.
Comparative human in-vivo study of an immediate release tablet over-encapsulated by gelatin and hydroxypropyl methyl cellulose capsules – impact of dissolution rate on bioequivalence.
Pentapack advanced unit dose pharmaceutical blister packaging systems offer the unique capability to package both solid and liquid dose medications with one machine. Medications are clearly identified with bar code labeling software and high resolution label printing.
Using a cyclone on the extraction line facilitates interception of this powder before it ever leaves the process room, enabling high integrity batch reconciliation and minimizing filter replacement.
The 9505 stainless steel pneumatic conveyor is designed for the transfer of empty 00-5 sized capsules. Capsules are emptied into a collection container and dispensed at an adjustable rate into a capsule-filling machine. This unique conveyor uses air power to push the capsules through rigid sanitary piping into a hopper above the capsule-filling machine without damaging the capsules. The Nilfisk product conveying process takes place in perfect hygienic conditions, respecting both the environment and the operators’ health.
Pneumatic conveyors move powder and granules from sacks, big bags or other containers to the required location in selected quantities and within the desired time. The Nilfisk product conveying process takes place in perfect hygienic conditions, respecting both the environment and the operators’ health.
With Metrics Contract Services’ extensive capabilities, you can keep your drug product development, clinical trial materials and commercial manufacturing all under one roof. From teacup-size batches and up, Metrics Contract Services provides high quality drug product contract manufacturing for both clinical trial materials and commercialization.
The homogenizer is working as a particles size reducer for particles in suspension in a liquid and to calibrate their size at a defined value.
A manual or automatic sampling valve can be adapted at the hopper or container powder outlet with a standard containment or bottle system.
The pneumatic POSITIVE pressure conveying (or PRESSURE conveying) is dedicated to the transfer of larger quantities of powder or granulates under following conditions:
