Blister package manufacturing consists of plastic formed into cavities that house the tablet or the capsules and then sealed on the back with a lidding material (usually aluminum foil, paper or plastic).
The Indian vaccine manufacturer Serum Institute of India has a vision – to continually increase the production of affordable, high-quality vaccines. The founder and owner Dr. Cyrus S. Poonawalla believes that every child in the world should be granted access to inexpensive bacterial and viral vaccines against Tetanus, Influenza or MMR (mumps, measles and rubella), to name just a few.
In numerous pharma companies, the following problem is being posed: shrinking lot sizes are constantly worsening the ratio of packaging system set-up time to running time. By Dr. Ralph Blum, Mediseal GmbH, Schloss Holte
Two years ago, Elaiapharm undertook the packaging of an important new solid dose product (Cipralex, an antidepressant) to be launched across a large number of international markets. The product itself is an ODT – orally dispersible tablet – formulation packed in child resistant cold form blisters.
At the end of the packaging process, the packaged syringes should meet the requirements for sterile devices in the operating room. Therefore, the finished blisters are autoclaved at 121 °C (2 bar) for 15 minutes. Only minimal deformation of the blisters is tolerated, so that the syringes can be used in the operating room without problems after this thermal treatment.
Volumetric feeding by means of a flowmeter, a method that has become established at Pharmatis, was also implemented in this project; the configuration was taken over by the Mediseal HMI. The feeding system is highly flexible and can be adapted to a wide range of products.
Pharmaceutical producers naturally want to utilize their machine capacities to the fullest in day-to-day business. The key words read efficiency, reliability and flexibility – all in line with the highest safety and cGMP standards. Modern and flexible equipment plays a major role in achieving maximum uptime and high quality in all packaging processes. “We always bear in mind our customer’s demands when developing new equipment or designing tailor-made line concepts. This is why all our machines and components are based on a modular concept,” Ralph Pfister, area sales manager at Bosch Packaging Technology, underlines.