Despite the benefits of blow-fill-seal (B/F/S) over glass, some pharmaceutical companies refuse to make the switch because of a number of objections. One of these is the high capital cost of B/F/S equipment. On the surface, the numbers can be intimidating, but a closer look reveals an investment in B/F/S may yield incredible long-term savings.
This method can be used to identify potential points of weakness in a film or seal during the manufacturing process by simulating circumstances whereby the material may burst during packaging and transport.
MDIs are designed to deliver precise/accurate and reproducible doses of the drug to the lungs or nose. Good performance is crucial as patients rely on their inhaler to deliver the required dose of medication at often crucial times.
The degree of stiffness of a blister pack will affect its effectiveness. Measuring the required force to push-through a blister pack is therefore necessary.
As the industry continues its move toward biologics, innovative solutions and technologies will be needed to ensure a safe and reliable approach to the manufacturing and delivery of these drugs.
he Serum Bio Pharma Park in Pune is the first of its kind in the country and was designed in strict compliance with cGMP (current Good Manufacturing Practice) standards.
In numerous pharma companies, the following problem is being posed: shrinking lot sizes are constantly worsening the ratio of packaging system set-up time to running time. By Dr. Ralph Blum, Mediseal GmbH, Schloss Holte