WHITE PAPERS & CASE STUDIES

  • Precision Powder In Capsule Micro Dosing Accelerates Drug Product Development

    Advancing active pharmaceutical ingredients (APIs) through the drug product-development lifecycle is fraught with challenges. Development timelines are tight, so it’s crucial to determine early in the process if an API is a viable candidate for clinical testing. A key tool that has emerged to address these combined issues of tight timelines and complex molecules is precision powder micro-dosing in capsules. This paper describes the use of precision micro-dosing to prepare API powder-in-capsule (PIC) dosage forms for oral or pulmonary administration.

  • Determination Of Moisture Permeation During Product Shelf Life

    How non-destructive headspace analysis information can be critical for QC groups performing stability studies, or for packaging development groups responsible for choosing the optimal packaging.

  • Lyo Chamber Moisture Mapping

    Rapid non-destructive headspace moisture analysis from LIGHTHOUSE enables fast moisture determination of statistical numbers of lyo samples.

  • Root Cause Investigation Into A Possible Container Closure Integrity Failure

    In cases where oxidation of the formulation causes discoloration and eventual degradation of the product, non-destructive headspace analysis tests can give deep insight into the root cause. Since the samples are not destroyed by the headspace analysis, further testing can be done to accurately correlate headspace conditions with other product characteristics.

  • Redefining Fast Melt For Pharma With 3D Printing

    Adults and children alike often struggle with compliance and acceptance of medication regimens due to the sizes and shape of prescribed tablets. One pharmaceutical manufacturer sought to create a convenient, easy-to-swallow dosage form by taking an alternative approach: three-dimensional printing (3DP). This white paper outlines their approach to creating an FDA validated manufacturing process for rapidly disintegrating dosage forms.

  • 5 Steps To Increase Energy-Efficient Mixing

    Mixer testing simulation trials are needed to confirm the suitability of a specific mixing strategy. This white paper explores five ways to increase energy efficiency in new and existing mixing processes.

PRODUCTS & SERVICES

End-To-End Vial Line Capabilities Deliver Reliable Speed to Market
End-user convenience continues to influence packaging as more consumers turn to smaller products that can be easily stored in travel bags, purses, or even gym bags. In the face of increasingly strict airline regulations, travelers are challenged by limitations in carry-on luggage contents.

With many of the blockbuster biologic drugs of the ’90s are coming off of patent, companies are racing to provide a clinically similar alternative to these pioneering products. Like any biologic drug, they require care and attentiveness throughout the manufacturing process. Therefore, it is necessary to maintain aseptic conditions throughout the production process of these drug products.

Dec offers pharmaceutical filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.

Dec’s ability to provide end-to-end solutions from API manufacturing to primary packaging filling covers the complete range from R&D processes and small batches to large filling campaigns. Our solutions include state of the art robotics for the filling and handling of complex delivery systems like pre-filled syringes (PFS).

If you are looking for filling systems for different products such as liquids, powder or flow-resistant highly viscous materials, Dec provides a modular concept allowing to meet a variety of packaging that is appropriate in the field of research and development as well as clinical trials. Speed up your go-to-market strategy with innovation and modular thinking.

Dec offers filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.

Used Lock metal check model MET30+, approximately 3.75" x 0.75" opening, 115 volt, serial# 21315/3, built 2004.

Used Key International capsule polisher, model CP350, stainless steel product contact surfaces, on stand with empty capsule reject, no brush, serial# JI2823.