Formulation Development Applications & Studies

1. Integrating High-Content Imaging With Traditional Plate-Based Screening 5/6/2026

   Gain mechanistic insights beyond traditional viability assays, revealing nuanced cellular phenotypes and strengthening early drug discovery decisions without sacrificing throughput or efficiency.

2. Accelerating Discovery Success With Structure-Guided Drug Design 5/6/2026

   Structure‑enabled drug discovery revealed a novel, druggable binding site in Artemis, enabling rapid SAR optimization and a ~500‑fold potency improvement against a challenging oncology target.

3. Predicting Performance Of Lotions Through Rheological Characterization 5/6/2026

   Rheological testing shows how small formulation differences influence spreading, flow, and feel during use. With minimal sample volumes, these methods connect lab measurements to real‑world performance.

4. Rheology Is An Accurate Predictor Of Pharmaceutical Lotion Stability 5/6/2026

   Rheological creep testing provides a rapid way to predict pharmaceutical lotion stability by linking steady-state viscosity to particle settling behavior, enabling reliable shelf-life estimates.

5. Maintain Control Of Pharmaceutical Water Systems 4/10/2026

   Early TOC excursions often reveal hidden risks in water systems. Capturing samples at the moment of deviation helps teams confirm root causes faster, reduce uncertainty, and maintain control.

6. Evaluating Carryover When Using A TOC Analyzer 4/10/2026

   Accurate TOC results shouldn’t depend on sample order. See how low-level measurements remain reliable even after high-TOC analysis, helping reduce false positives and streamline decisions.

7. Scale-Up Of AAV Production In Fixed-Bed Bioreactors 3/31/2026

   Consistent AAV production is critical for manufacturing. See how aligned strategies deliver comparable cell growth, metabolic trends, and rAAV5 titers from development through production.

8. Cost Modeling Analysis Of AAV And LV Manufacturing 3/31/2026

   Manufacturing scale plays a critical role in viral vector economics. Compare AAV and LV production scenarios to gain insight into how intermediate-scale strategies can reduce cost and risk.

9. Overcoming Food Effects, Variability, Solubility For A Non-Opioid Analgesic With Lipid-Based Formulations 3/20/2026

   Develop optimized lipid-based formulations to overcome solubility, stability, and food-effect challenges, enabling high-dose oral delivery and rapid progression to Phase 1 trials.

10. Overcoming API Constraints And Tight Timelines With On-Demand Manufacturing 3/20/2026

    Use innovative lipid-based formulations and on-demand manufacturing to accelerate Phase 1 trials, enable flexible dose escalation, and maximize limited API for poorly soluble compounds.