Formulation Development Applications & Studies

1. Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A Resins 8/27/2026

   Protein A chromatography intensification can increase productivity, but it may also affect process robustness. Explore key tradeoffs, operational challenges, and practical considerations.

2. Detect Low-Abundance GLP-1 Impurities With Greater Sensitivity 8/24/2026

   Low-level impurities can be difficult to resolve using conventional approaches. Discover how a Charged Surface 2.3 µm superficially porous Phenyl-Hexyl column enhances reversed-phase LC-MS analysis.

3. Differentiate Challenging Site-Specific Isomeric Amino Acids 8/24/2026

   Learn how high-resolution ion mobility, pre-IMS fragmentation, and product ion analysis can resolve difficult peptide isomers and localize structural differences, supporting confident characterization.

4. Increase Throughput For Intact Mass Confirmation And Impurity Screening 8/24/2026

   Accelerate intact mass analysis of GLP-1 analogues with automated purity calculations, sub-ppm mass accuracy, and impurity detection for consistent results in under one minute per sample.

5. Integrated QC As A Development Strategy: Reducing Late-Stage Analytical Risk 8/20/2026

   Learn how early QC integration, proactive analytical risk management, and cross-functional collaboration can improve validation readiness, reduce development surprises, strengthen release testing predictability, and help protect critical clinical manufacturing timelines.

6. Accelerating Phase: Supply Without Sacrificing Discipline 8/20/2026

   Faster clinical supply delivery starts with the right strategy. Explore how planning, collaboration, communication, and quality systems keep programs on track.

7. Oral Delivery Of PROTACs: Integrating Molecular Design And Enabling Formulation 8/20/2026

   Explore how integrated molecular design and formulation strategies can overcome the unique oral-delivery challenges of PROTACs, transforming complex degraders into viable, scalable medicines.

8. Evaluating Clone Performance And Cell-Specific Productivity 8/6/2026

   See how continuous process monitoring and automated at-line analytics support confident CHO clone ranking, consistent cultivation, and scale-up by connecting pH, viable cell density, and more.

9. A Comparison To Traditional Clone Screening Platforms 8/6/2026

   See how 46 CHO clones performed across automated, deep-well, and microbioreactor fed-batch cultures, using cell density, viability, and IgG concentration to evaluate clone performance.

10. A Sensory Panel Study With The Focus On High-Intensity Sweeteners 8/5/2026

    Gain insight into the sensory performance of five high-intensity sweeteners in a simulated bitter formulation, including their effects on sweetness, bitterness, aftertaste, and covering ability.