Formulation Development Applications & Studies

  1. Improving API Solubility Using Spray Drying With Polyvinyl Alcohol 6/5/2025

    Enhancing the solubility of poorly soluble APIs is vital for improving bioavailability and therapeutic outcomes. Discover how advanced formulation techniques like hot-melt extrusion and spray drying can overcome this challenge.

  2. API Solubility And Dissolution Enhancement Via Formulation 6/4/2025

    Solubility and dissolution rate of an API are essential for effective oral drug absorption. Discover how these factors directly influence bioavailability, which determines how much and how quickly a drug enters circulation.

  3. Versatile Lipid Nanoparticle Platform For Efficient Gene Editing 6/3/2025

    Lipid nanoparticles enable efficient gene editing in hard-to-transfect cells like T-cells and blood stem cells, which offers scalable, clinically relevant methods for developing advanced therapies for cancer and rare diseases.

  4. Benchmarking Filtration Performance Of TFF Cassettes 5/30/2025

    Optimize your protein purification workflow with tangential flow filtration by comparing membrane performance and exploring how protein concentration impacts flux and MWCO selection in lab-scale systems.

  5. Flow Chemistry Experiments Of Highly Hazardous Butyl Lithium Reactions 5/22/2025

    By adopting flow chemistry for a production platform that reduces utility costs and solvent consumption, researchers can overcome the risks and challenges of Butyl Lithium chemistry.

  6. In Vitro/In Vivo Permeability: A 4-Cell Line Study 5/21/2025

    Evaluate drug absorption potential across diverse cell barriers and transporter systems using our comparative permeability studies with a variety of cell lines and standard compounds.

  7. Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs 5/16/2025

    By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.

  8. Modelling TPDs Utilizing Computational And Medicinal Chemistry Approaches 5/16/2025

    Through a carefully executed strategy, see how we identified novel degrader molecules with the right physicochemical properties to achieve robust degradation of the target Protein of Interest (POI).

  9. Enabling Transfer Of Raman Calibration Models Across Bioreactor Scales 5/16/2025

    Raman spectroscopy has revolutionized manufacturing through real-time monitoring. Explore a system that enables a seamless calibration model transfer from small- to large-scale bioreactors to enhance scalability and efficiency.

  10. Pharmacokinetic Study Of Salbutamol Through Nose Only Exposure In CD-1 Male Mice 5/13/2025

    Explore how using advanced tools like the inExpose system can provide precise measurements of lung and plasma drug concentrations to optimize inhalation therapy for pulmonary treatments.