Formulation Development Applications & Studies

31. Developing A Quantitative Surrogate Peptide Assay 7/17/2025

    Discover a streamlined LC-MS/MS workflow for Fc-containing therapeutics like dulaglutide to enable precise quantification with LLOQ as low as 1 ng/mL through automated, efficient assay development.

32. Bioanalytical Quantification Of A Biotherapeutic Peptide 7/17/2025

    Discover a sensitive, selective, and robust LC-MS method for quantifying semaglutide in plasma with advanced sample preparation and detection technologies for accurate results in bioanalytical research.

33. Use Of Reconstructed Tissue And 3D Printed CT-Based Nasal Casts 7/3/2025

    Reconstructed nasal epithelium and CT-based 3D nasal casts provide more predictive, physiologically relevant models for assessing nasal drug delivery, improving accuracy in formulation development.

34. N-1 Perfusion High Inoculum Fed-Batch For Reduced COGS And Easy Retrofit 6/30/2025

    Discover a company that tripled productivity and cut costs by optimizing its seed train process to achieve major gains without infrastructure expansion.

35. Modular Facilities With Smaller Footprint Through Dynamic Perfusion 6/30/2025

    Discover how a top CDMO leveraged dynamic perfusion technology to boost biomanufacturing throughput, cut capital costs, and enable flexible, multi-modality production.

36. Merck Process Transfer And Scale-Up Of Batch Protein A 6/30/2025

    Explore cost-saving innovations in purification using a system that achieves consistent product quality and yield while significantly reducing resin use and enhancing large-scale efficiency.

37. Success Story: Increased Productivity With Concentrated Fed-Batch 6/30/2025

    Discover how a leading biopharma company boosted flexibility and quadrupled productivity by implementing a concentrated fed-batch process in a single-use facility.

38. Improving Consumer Safety Through Innovative Science 6/27/2025

    Liquid chromatography revolutionizes science with precision. Discover a technology that leads the charge in enhancing HPLC performance for breakthroughs in health, safety, and environmental research.

39. Development Of Separation Methods for GLP-1 Synthetic Peptides 6/27/2025

    Peptides offer precise, low-cost therapeutic potential, especially in GLP-1 drugs for diabetes and weight loss. A new HPLC-UV/MS method ensures consistent quality and analysis of these compounds.

40. Blood Brain Permeability And CNS Bioavailability Of Targeted Protein Degraders 6/20/2025

    Evidence suggests that the inherent flexibility of Targeted Protein Degraders (TPDs) can be leveraged to optimize key parameters such as solubility, permeability, and oral bioavailability.