Formulation Development Applications & Studies

  1. Developing Amorphous Solid Dispersions For Poorly Soluble Drugs 6/20/2025

    Discover how a strategic amorphous solid dispersion approach improved bioavailability and advanced a low-solubility compound toward clinical readiness in just four weeks.

  2. Advancing In Silico Predictions In Early Drug Discovery 6/20/2025

    Examine a high-throughput approach that streamlines LogD measurements, offering faster and more accurate insight into compound lipophilicity to support better decision-making in early drug discovery.

  3. Elevating Purity: Racemizing Pharmaceutical Products In Flow Microreactors 6/18/2025

    Discover how our process development team resolved a racemization challenge by delivering a biologically active racemic mixture while maintaining compound purity.

  4. Designing Protocols For A 40% Emulsifiable Concentrate Of A Systemic Insecticide 6/13/2025

    Explore how formulation expertise can help overcome the complex challenges of developing stable, effective, and regulatory-compliant emulsifiable concentrate (EC) formulations for crop protection.

  5. Column Head Loading In SFC: A Novel Injection Technique For Polar Heterocycles, Oligopeptides 6/13/2025

    By improving sample loading uniformity and reducing solubility-related artifacts, see how a multiple-injection approach enhances the practicality and effectiveness of SFC for difficult-to-purify substances.

  6. Leveraging Surface Plasmon Resonance For Characterizing Ternary Complexes 6/13/2025

    Uncover how Surface Plasmon Resonance (SPR) can be used to gain real-time, label-free insights into PROTAC binding kinetics and ternary complex formation.

  7. Modifying The Micro-Environment To Improve Dissolution Rate 6/11/2025

    Discover how modifying the micro-environment with targeted excipients can significantly enhance the dissolution rate of poorly soluble drugs using conventional manufacturing methods.

  8. Improving API Solubility With Mesoporous Silica 6/5/2025

    Poor solubility of active pharmaceutical ingredients can hinder drug effectiveness. Learn how innovative formulation strategies enhance solubility and bioavailability to improve therapeutic outcomes for challenging drug candidates.

  9. Improving API Solubility Using Spray Drying With Polyvinyl Alcohol 6/5/2025

    Enhancing the solubility of poorly soluble APIs is vital for improving bioavailability. Discover how advanced formulation techniques like hot-melt extrusion and spray drying can overcome this challenge.

  10. API Solubility And Dissolution Enhancement Via Formulation 6/4/2025

    Solubility and dissolution rate of an API are essential for effective oral drug absorption. Discover how these factors directly influence bioavailability, which determines how much and how quickly a drug enters circulation.