Formulation Development Applications & Studies
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Delivering Pre-IND To IND Safety Studies In Just Three Months
11/29/2022
A biotech company partnered with an integrated research, development and manufacturing services company to deliver pre-IND to IND safety studies for a treatment therapy for gut-brain diseases.
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Generating A Robust Host Cell Line For A Cell Line Development Platform
11/14/2022
Learn how cell performance within the context of the cell line development workflow was confirmed with the successful isolation of stable, high-producing clones from three model monoclonal antibodies.
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Middle-Up Mass Analysis Of Protease Digested Cetuximab
10/24/2022
Explore a complete reversed phase UHPLC-MS workflow, developed to simplify middle-up mass analysis of an immunoglobulin G antibody, from the antibody purification, proteolysis, and reduction to its UHPLC-MS analysis.
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Tailoring The Expansion Process And Process For Longer Workflows
10/17/2022
This article addresses the focus on the variability and importance of having robust young (TCM) populations for efficacious therapies.
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Improving Workflow Automation And Process Control
10/17/2022
Learn about optimizing your T cell manufacturing process and reducing operating costs with rocking bioreactors using CTS OpTmizer T Cell Expansion SFM.
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Impact Of Media, Stirred-Tank Bioreactors On Cell Therapy Manufacturing
10/14/2022
Rocking motion bioreactors have long been the mainstay in T-cell therapy, but stirred-tank bioreactors have garnered a lot of excitement because of several potential advantages.
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Method Transfer Of A USP Organic Impurities Method To An Arc HPLC
10/7/2022
Learn about a global interlaboratory method transfer study of a USP impurities method that was conducted at eight participating sites.
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The Journey To AAV Production In Suspension – Scaling-Up Your Process
9/27/2022
We present a simple protocol for scaling up AAV production using HEK293 host cells cultured in suspension and under serum-free conditions.
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Workflow For Antibody Aggregate And Fragment Analysis
9/27/2022
Characterizing mAb aggregate and fragment formation during drug formulation and establishing a suitable quality control process is essential. Learn about a complete workflow for antibody aggregate and fragment quantification.
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Advancing A Cell Therapy Drug To The Clinic: Safety Tox Package
9/26/2022
Cytopeutics, a provider of mesenchymal stem cells (MSC) for clinical trials and treatment, needed to conduct safety and tumorigenicity studies in appropriate animal models for its hMSC product.