Formulation Development Applications & Studies

  1. Automating High-Throughput Screens Using Patient-Derived Organoids 3/17/2025

    Many oncology drugs fail in later development stages due to inadequate predictive models. Explore how 3D cell models, like patient-derived organoids, offer a promising solution in the drug development process.

  2. Automated Testing For Compound Toxicity Effects 3/17/2025

    Explore how anti-cancer drugs' toxic effects on intestinal cells limit dosages as well as how 3D organoids and assay automation can enhance drug development by improving testing processes.

  3. Assessing Viability And Real-Time Apoptosis/Necrosis 3/17/2025

    Malignant gliomas are aggressive brain tumors that resist standard treatments. Discover why researchers focus on real-time cell death dynamics to develop targeted therapies and promising strategies.

  4. Rapid Automated Selection Of Mammalian Cell Colonies 3/17/2025

    Discover how a new technology cultivates mammalian cells into clonal colonies and images them using fluorescent assays to isolate clonal cell populations based on surface protein expression.

  5. AI-Enabled Phenotypic Analysis Of Label-Free Intestinal Organoids 3/10/2025

    Discover how advanced 3D models and AI-enabled imaging techniques revolutionize organoid research, which provides accurate phenotypic analysis to monitor growth and development in various organoid types.

  6. 3D Cell Culture Reveals Undetectable Drug Efficacy In Traditional Systems 3/10/2025

    Drug discovery now targets cancer stem cells (CSCs) to achieve long-term tumor eradication, which moves beyond traditional chemotherapeutics. Discover an advanced screening platform that better predicts CSC inhibitor efficacy.

  7. Transforming A Liquid Protein Solution Into A Solid Oral Dosage Form 3/4/2025

    Unlocking the potential of oral protein therapeutics requires innovative formulation and manufacturing strategies to overcome stability, absorption, and bioavailability challenges.

  8. Rheological Properties Of Pharmaceutical Excipients: Lactose Monohydrate And Carboxymethyl Cellulose 12/30/2024

    Explore lactose monohydrate and CMC rheology, highlighting their flow, cohesion, and compressibility properties to optimize pharmaceutical formulations under varying stress and temperature conditions.

  9. Characterization Of Pharmaceutical Materials With Modulated DSC 12/30/2024

    Modulated DSC addresses challenges in pharmaceutical material characterization, enabling precise analysis of glass transitions, and overlapping transitions, enhancing insights beyond standard DSC.

  10. Thermal Analysis In The Pharmaceutical Industry 12/30/2024

    Thermal analysis techniques provide valuable insights into pharmaceutical material properties, ensuring compatibility, stability, and quality control in drug development and production processes.