Formulation Development Applications & Studies

  1. An Alternative Method Of Drug-Excipient Characterization 12/30/2024

    Isothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.

  2. Expanding The OSD Toolbox: An Industry Approach To Adsorb Lipids Onto Powder Substrates 12/11/2024

    Explore innovative solutions for improving the solubility and bioavailability of poorly soluble compounds in solid oral dosage forms to enhance drug delivery and therapeutic effectiveness.

  3. Integrating Phase-Appropriate Quality Standards 12/9/2024

    Incorporating phase-specific quality standards ensures GMP compliance throughout biopharmaceutical development. Collaborating with an experienced CDMO addresses late-stage quality needs and efficiently manages accelerated product development timelines.

  4. Monolithic Columns As Downstream Processing Solutions For Lentiviral Purification 11/27/2024

    Third-generation lentiviral vectors enable efficient gene delivery, but purification challenges limit in vivo applications. Monolithic columns and advanced assays show promise for downstream processes.

  5. Innovating The mAb Characterization Process 11/14/2024

    Understanding the characteristics of a molecule's "personality" is crucial for optimizing development and manufacturing. Learn how to overcome the challenges in the characterization process.

  6. A Human-Relevant Model Of The Liver Sinusoid 11/7/2024

    This organ-on-a-chip model minimizes drug absorption while maintaining the essential architecture. Explore the specifications of this product engineered to model the human liver.

  7. Achieving Optimal CAR-T Cell Generation 10/9/2024

    Discover the innovative methods behind CAR-T cell production, from custom plasmid design to lentiviral vector transduction, and explore their potential in revolutionizing cancer treatment.

  8. AAV Empty/Full Ratio Assessment Using The Octet® AAVX Biosensors 9/27/2024

    Learn about a rapid, high-throughput method for determining the E/F ratio in the AAV drug product that is well-suited for screening both crude and purified AAV samples.

  9. Rapid, Automated, At-Line Adenovirus Quantitation 9/27/2024

    Gain insight into how a high-throughput capsid assay for rapid AV quantification was developed using an innovative Bio-Layer Interferometry (BLI) platform that offers high precision and reliability.

  10. Lightning-Link® Conjugation Kits: Consistent Performance On A Broad Scale 9/26/2024

    Learn about labeling technology offering a transformative solution through direct antibody labeling without the need for post-conjugation purification, thereby mitigating antibody loss and ensuring reproducible results.