MilliporeSigma Application Notes & White Papers
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Comparative Study On Secondary Contamination Risk
1/31/2024
Accurate testing results are crucial for product safety. Explore the findings of a comparative study evaluating two different platforms for the membrane filtration of microorganisms in quality control.
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Testing Cell-Based Immunotherapeutics For Microbial Contaminants
10/23/2023
In this study, two different immune cell preparations were evaluated for their compatibility with the Milliflex® Rapid System to establish a USP and EP compliant method for rapid sterility testing.
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Detection Of Low Bacterial Contamination From Neoprene® Gloves With ICR Swabs
9/22/2023
This study was designed to prove the suitability of ICR Swabs and lockable TSA w. LTHThio contact plates to detect low numbers of different bacterial test strains from Neoprene® gloves.
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Detection Of Low-Level Bacterial Contamination Using ICR Swabs And Contact Plates
9/22/2023
Contact plates and swabs are commonly used for surface monitoring in aseptic manufacturing. Here, we demonstrate the recovery rates of MilliporeSigma’s ICR Swabs and lockable TSA w. LTHThio contact plates.
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How To Use MAS-100® Air Samplers With BioTrends EM® System
9/22/2023
Environmental monitoring plays an important role in pharmaceutical manufacturing contamination control. Learn how MilliporeSigma and the BioTrends EM® software system pair together for your data analytics.
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Implementing High Cell Density Cryopreservation In Your Seed Train
1/22/2023
Simplify seed train intensification with high cell density cryopreservation. Eliminate the need for manual scale-up steps and enable risk reduction through closed banking and inoculation processes.
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Middle-Up Mass Analysis Of Protease Digested Cetuximab
10/24/2022
Explore a complete reversed phase UHPLC-MS workflow, developed to simplify middle-up mass analysis of an immunoglobulin G antibody, from the antibody purification, proteolysis, and reduction to its UHPLC-MS analysis.
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UHPLC Analysis Of Vitamin D2 & D3
10/21/2022
Here, we demonstrate the use of the Supel™ Carbon LC UHPLC column to baseline separate the vitamin D2 and D3 forms from the D2 and D3 epimers.
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Workflow For Antibody Aggregate And Fragment Analysis
9/27/2022
Characterizing mAb aggregate and fragment formation during drug formulation and establishing a suitable quality control process is essential. Learn about a complete workflow for antibody aggregate and fragment quantification.
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Supel™ BioSPME 96-Pin Device Comparison To Rapid Equilibrium Dialysis Technique
4/9/2022
Here, we review a technology that has been demonstrated to significantly reduce the time required for protein binding determination when compared with the rapid equilibrium dialysis method.