MilliporeSigma Application Notes & White Papers

  1. Evaluation Of Extractables And Physical Compatibility Of The Mobius® ADC Reactor Single-Use Components For ADC Manufacturing 10/29/2024

    Explore study results evaluating the physical compatibility of single-use components in the Mobius® ADC Reactor and the level of extractables when exposed to dimethyl sulfoxide and dimethyl acetamide.

  2. Performance Of Mobius® Bag Assemblies With Ultimus® Film In Truck Shipping Simulation Test 10/29/2024

    Explore findings from a study testing Mobius® single-use bags under rigorous shipping conditions, demonstrating the suitability for transporting various liquid volumes while preserving their integrity.

  3. Mobius® ADC Reactor Performance 10/22/2024

    Learn about a family of single-use ADC reactors that has been developed to offer a safer and more efficient ADC production method than traditional mixing systems and meet the industry's growing needs.

  4. Accelerating Bulk Harvest Release Testing With A PCR-Based Solution 7/3/2024

    Adventitious agent testing is frequently a bottleneck in downstream processing. Discover a PCR-based solution for manufacturing processes using CHO cells and animal origin-free components.

  5. Sterility Testing Of Products With Antimicrobial Properties 6/4/2024

    Drugs formulated with antibiotics, preservatives, or other chemicals may inhibit microbial viability and growth. Learn more about three golden rules to be effective against antimicrobial effects.

  6. Sterility Testing Of Products To Be Diluted In Isopropyl Myristate 6/4/2024

    Discover one possible test set-up to dilute a product in isopropyl myristate, filter it, and rinse the membrane to eliminate residues that may inhibit microbial growth.

  7. Overcoming The Solubility Challenges Of Antibody-Drug Conjugates 6/3/2024

    Discover a chito-oligosaccharide that significantly improves the solubility of antibody-drug conjugates (ADCs) when included in the linker-payload construct.

  8. Comparative Study On Secondary Contamination Risk 1/31/2024

    Accurate testing results are crucial for product safety. Explore the findings of a comparative study evaluating two different platforms for the membrane filtration of microorganisms in quality control.

  9. Testing Cell-Based Immunotherapeutics For Microbial Contaminants 10/23/2023

    In this study, two different immune cell preparations were evaluated for their compatibility with the Milliflex® Rapid System to establish a USP and EP compliant method for rapid sterility testing.

  10. Detection Of Low Bacterial Contamination From Neoprene® Gloves With ICR Swabs 9/22/2023

    This study was designed to prove the suitability of ICR Swabs and lockable TSA w. LTHThio contact plates to detect low numbers of different bacterial test strains from Neoprene® gloves.