Production Featured Articles

51. Implementing Small-Scale Models For Biopharmaceutical Development 5/12/2021

    Small-scale models (SSMs) are widely used for process development and optimization, scale-up, technology transfer, process characterization, process validation, and more. This article from a BioPhorum Development Group discusses the applications of the models, including viral clearance, quality oversight, and design considerations for justification of SSMs.

52. What You Need To Know About Manufacturing OTC Products 5/4/2021

    As more medications move to OTC status, people are interested in playing a more active role in managing their health and controlling their healthcare choices. However, self-medication comes with risks.

53. Scale-Up: The Next Mountain To Climb In Technology Transfers 5/4/2021

    Turning a promising drug candidate into a successful pharmaceutical product involves scaling-up the processes so a commercial supply can be achieved, which involves technical hurdles.

54. What Is The Best Way To Scale-Up The Manufacturing Process For My Pharmaceutical Product? 5/4/2021

    With the bright promise of ramping sales and distribution comes the immediate challenge of identifying the most optimal manufacturing strategy to maximize your product’s market acceptance. Take a closer look at the most important parameters to consider for a successful scale-up.

55. How A CDMO Can Increase The Competitiveness Of Your Product 5/4/2021

    Simple manufacturing outsourcing services no longer meet financial and environmental protection requirements. High-tech, value-added process development and industrial application represent the future development trend of the pharmaceutical outsourcing industry.

56. Consistency And Compliance Through Cell Therapy Automation Software 4/30/2021

    As automation offers new options for flexibility and optimized production in biologic production, exploring its use in advanced therapy manufacturing to improve safety, quality, and compliance becomes a key factor in advancing patient care.

57. Mixing Cannabis-Infused Products 4/23/2021

    Gain insights from a pharmaceutical equipment manufacturer on factors cannabis manufacturers should consider when they're looking to purchase a mixer.

58. Innovative Single-Use Bioreactors Built To Deliver High-Volume Performance 4/23/2021

    A new generation of single-use bioreactors allows intensified, flexible manufacturing, enhanced by high-power input per volume, and better volumetric mass transfer performance.

59. Manufacturing Therapeutics In Hospitals: Re-envisioning The Bioprocessing Paradigm 4/19/2021

    Most hospital-based therapies are “patient ready,” pulled from inventory and used with minimal preparation. However, advanced therapy medicinal products (ATMPs) are changing how we think about how we deliver therapies. The success of these new and complex therapies requires partnership with those administering them, which is a new paradigm.

60. Viral Vector Scale-Up: How Can We Bridge The Technology Gaps? 4/15/2021

    <p&GTUnlocking the full potential of viral-vector based therapies requires an understanding of existing challenges in viral vector production and which technologies are now available in upstream and downstream processing to help address them.</p&GT