FEATURED ARTICLES
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Valves And Control Heads: A Combination To Facilitate The Next-Generation Of Plants
Maintaining sterile process conditions is a vital but daunting task for manufacturers. Separation processes like filtration and chromatography place considerable demands on sterile systems and must be done properly to ensure the purity of media.
WHITE PAPERS & CASE STUDIES
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Modular Facility Design: A Cost-Effective Option In The Post-Blockbuster Drug Era
The pharmaceutical industry has undergone a sea of change in recent years as manufacturers have adapted to the end of the era of large-volume production of mass-market blockbuster drugs. With firms now focusing in on subpopulations of patients, there is a need for lean, adaptable facilities that can switch quickly between multiple products in multiple formats. Modular facilities can meet this need. While not a panacea, for the right project characteristics, ‘Modularity in Design’ can deliver significant and quantifiable long-term value.
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Medication Errors -- A Threat To Patient Safety: Mitigating Errors With Tablet Appearance
Medical prescription drug errors by doctors, pharmacists and patients account for 1.5 million incidences of sickness, injuries or deaths in the U.S. each year. By Jay Anbil and Steve Yoder
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Film Coating For Pediatric Oral Solid Dosage Forms
From a recent survey conducted within the pharmaceutical industry, by Colorcon, it was confirmed that oral solid dosage forms are a preferred choice for formulation of pediatric medicines.
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Accelerating Lipid-Based Drug Formulation
Formulation scientistsmust develop and validat robust systems that address the challenges posed by increasingly complex drug candidates, in ever shortening time frames.
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When Capsules Fall Apart, Who Is To Blame?
Capsule integrity is a given for established manufacturers with impeccable reputations. Consumers, however, know from experience that not all capsules are made equal. Some can be difficult to extract from the blister pack. Others may have gel caps with cracks or, even worse, ruptures that allow the ingredients to spill out. Is this a manufacturing problem? Or has R&D neglected to implement a fool proof test methodology for evaluating capsule stability? Compression and tension testing offer a technical approach with quantifiable results that can be used to assess capsule performance.
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How To Administer Insoluble Active Pharmaceutical Ingredients
Some active pharmaceutical ingredients are not soluble. In fact, more than 40% of new chemical entities developed in the pharmaceutical industry have little or no solubility in water.
PRODUCTS & SERVICES
Coperion K-Tron can provide single source solutions for all feeding and conveying needs in the pharmaceutical and nutraceutical industries. The complete Coperion K-Tron line of pharmaceutical equipment is engineered to meet the rigid requirements of the industry.
The ZSK 18 MEGAlab laboratory extruder is the smallest member of the ZSK family. This targeted and further development of proven ZSK technology extends the performance range of the series for R&D and production.
Coperion K-Tron vacuum sequencing receivers are designed to high quality standards for pneumatically conveying powders, pellets and granular materials for the bulk material handling industries.
Coperion K-Tron provides a variety of control options to meet a client's process needs. From standard equipment controls to interface options for both the pneumatic conveying systems as well as feeder controls, Coperion K-Tron is dedicated to ensure the client's specific process control requirements are met.
With over 100 years of experience in feeding technology, Coperion K-Tron development and engineering teams have created smart feeding solutions. Without consistent, dependable feeder accuracy and repeatability for your process, the integrity of any recipe—and hence the final product—will be compromised.
Coperion K-Tron's machine controllers and operator interfaces deliver full functional flexibility and the connectivity you need. Coperion K-Tron’s SmartConnex control environment provides comprehensive control capability with maximum flexibility and connectivity for systems up to 24 weigh belt feeders, loss-in-weight feeders, volumetric feeders, batchers, flow meters, Bulk Solids Pump (BSP) feeders or PID controlled devices as well as pneumatic refill systems.
Coperion K-Tron’s liquid loss-in-weight feeders provide accurate continuous volumetric or gravimetric flow control of liquids. The highly accurate gravimetric units combine the pump and tank with a suspension scale or platform scale; the feed pump for metering the material is located outside the scale area.
When handling powder and pellets, a plant constructor can only design a reliably functioning and economical bulk material handing system with in-depth knowledge and comprehensive understanding of the complex behavior of bulk materials.