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WHITE PAPERS & CASE STUDIES

  • Blow-Fill-Seal For Biologics: Breaking Through The Glass Ceiling Of Pharmaceutical Packaging
    Blow-Fill-Seal For Biologics: Breaking Through The Glass Ceiling Of Pharmaceutical Packaging

    As the industry continues its move toward biologics, innovative solutions and technologies will be needed to ensure a safe and reliable approach to the manufacturing and delivery of these drugs. One option is to leverage the advanced aseptic manufacturing of blow-fill-seal (B/F/S) technology, which has the potential to address the challenges of traditional glass filling as well as the global distribution of biologics.

  • Manufacturing Plants Based On The Lego Principle
    Manufacturing Plants Based On The Lego Principle

    Smaller batches and different types of product in the same plant – these are the market demands to which more and more manufacturers in the process industries need to adjust. The answer is plants based on the “Lego principle”. Users can add modules or switch them off in line with requirements.

  • Texture Analysis: Comparison Of Moisturizing Cream By Back Extrusion
    Texture Analysis: Comparison Of Moisturizing Cream By Back Extrusion

    Moisturising creams serve to keep the skin feeling smooth, soft, and looking radiant and healthy by retaining moisture or water in the outer most skin layer. Different moisturising creams will be defined by their viscosity or thickness. Formulating moisturising creams therefore largely depends upon the required end product consistency, influencing the choice of material to use.

  • Texture Analysis: Testing Viscosity Of Creams
    Texture Analysis: Testing Viscosity Of Creams

    Formulating moisturising creams largely depends upon the required end product consistency, influencing the choice of material to use.

  • Meeting US Pharmacopeia Standards For Triethyl Citrate
    Meeting US Pharmacopeia Standards For Triethyl Citrate

    Anton Paar's Generation M density meters and Abbemat refractometers deliver accurate and repeatable measurement results while providing system security for 21 CFR Part 11 compliance.

  • High Potency Containment For Polypeptide Vaccine Manufacturing
    High Potency Containment For Polypeptide Vaccine Manufacturing

    The team at Polypeptide Labs' overall project aim was to achieve homogenization (blending/tumbling) of potent lyophilized polypeptide product offloaded from a separate isolator.

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PRODUCTS & SERVICES

Consulting Services For Pharmaceutical Solid Dose Manufacturers Consulting Services For Pharmaceutical Solid Dose Manufacturers

At CRB, we understand that each manufacturer has unique needs. That is why we tailor our services to each client, ensuring that the solution you achieve is the best for you and not what was best for the last client. From Greenfield designs and major renovations, to troubleshooting a single piece of equipment, no issue is too big or too small. We pride ourselves in being our clients' long-term partner.
 

Fill/Finish Design Services Fill/Finish Design Services

Understanding the key drivers of your business – technology and regulatory requirements – is critical when designing or upgrading sterile and aseptic filling suites.

Aseptic Processing: Consulting And Engineering Services Aseptic Processing: Consulting And Engineering Services

At a time when pharmaceutical manufacturing operations are under tremendous pressures to improve effectiveness, deliver quality and reduce costs, CRB's aseptic processing experts are creating innovative solutions for the handling of potent and non-potent compounds in aseptic environments.

Process Simulation Services - Biopharma / Pharma Process Simulation Services - Biopharma / Pharma

Process Simulation can add value throughout the life-cycle of your facility: from master planning through start-up, de-bottlenecking and even day-to-day operations.

Virtual Design & Construction Services For Biopharma / Pharmaceutical Manufacturing Virtual Design & Construction Services For Biopharma / Pharmaceutical Manufacturing

VDC creates collaboration between all project stakeholders. Digital representations of physical and functional characteristics of a facility are generated and the resulting building information models become shared resources to support decision-making throughout your facility life-cycle. By incorporating BIM from the beginning of a project, you are empowered with in-depth knowledge of your facility.

Project Management Services For Biopharm / Pharmaceutical Manufacturing Project Management Services For Biopharm / Pharmaceutical Manufacturing

CRB's project managers take true ownership of your project, serving your interests and business at every phase of the project life-cycle. We oversee work, coordinate interface of other disciplines and stakeholders, facilitate all planning and communication, and drive performance to meet and exceed your expectations. At CRB, we want you to feel the Project Manager is an extension of your team and your on-site representative who ensures that your vision, scope and schedule are managed and achieved.

ONEsolution™: Engineering - Procurement - Construction Services For Pharmaceutical Manufacturing ONEsolution™: Engineering - Procurement - Construction Services For Pharmaceutical Manufacturing

Whether you refer to it as EPC (engineer-procure-construct) or design-build or integrated project delivery, CRB's ONEsolution™ integrates our in-house planning, design, construction, and commissioning and qualification into a structured, measurable, and efficient approach to achieve your project objectives. As a single, accountable and collaborative entity, CRB's multi-disciplinary teams partner with you to execute architecture, engineering, procurement, construction, safety, quality, regulatory inspection, commissioning, and management of your project. From concept to completion, our integrated, multi-disciplinary process allows for innovation and efficiency in achieving success for your project.

Facility Engineering Services For Biopharma / Pharma Manufacturing Facility Engineering Services For Biopharma / Pharma Manufacturing

CRB offers design solutions to meet the full range of your facility engineering needs. Our facility engineers provide worldwide experience in industries ranging from pharmaceuticals, biotech, science & technology, food, nutrition & consumer products and mission critical. Our technical strength combined with a 30 year history of hands-on experience with regulated facilities around the world ensure you have a facility design partner who you can rely on.

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