Natoli Products

  1. Pharmaceutical Preformulation Support Services 1/31/2024

    Partner with Natoli Scientific during the earliest stages. Our scientific expertise with state-of-the-art analytical capabilities is ready to take any preformulation challenge.

    Natoli scientific has an expertise of handling a wide range of APIs for the development of oral solids. We apply principles of ‘Quality by Design’ to define Critical Material Attributes (CMA), Critical Process Parameters (CPP), Critical Quality Attributes (CQA) and Quality Target Product Profiles (QTPP). Because we believe that understanding material and process as much as possible in the early life cycle of drug product development program is an insurance for further development path. Keeping your practices up to date with the ICHQ8 regulatory guidance issued by the US FDA. This is also a gate way for a smooth ride of product in the different stages of product development stages.

  2. Oral Solid Dose Formulation Troubleshooting Support Services 1/31/2024

    Natoli organization is a reputed leader with more than a half century experience in the tablet manufacturing technology.

    We understand tablets better. We are here for serving your needs to overcome challenges associated with commercial manufacturing of solid dosage forms across the globe (North America, Europe, Asia).

    Our Natoli scientific team uses holistic approach to understand and solve important tableting problems like capping, lamination, picking, and sticking. We integrate scientific information gathered at material, process, and instrument level to understanding and decode root causes of these common tableting issues.

  3. Pharmaceutical Tablet Presses 1/31/2024

    Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.

    With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.

  4. Pharmaceutical Double-Sided Rotary Tablet Press 3/30/2023

    INCREASED PRODUCTION RATE AND BETTER YIELDS=EFFICIENCY
    The NP-155 pharmaceutical tablet press is equipped with essential features that were designed and engineered to produce quality tablets at an affordable price. With its double-sided design, the NP-155 pharmaceutical tablet press produces two tablets per press turret cycle, allowing you to double your tablet production while running at standard single-sided rotary press speeds. The NP-155 provides significant versatility for delivering exceptional tablet quality, consistency, and production.

  5. Control Software For Production Tablet Presses: AIM™ Pro Plus 10/18/2019

    AIM™ Pro Plus Control System Makes Tablet Production Easy
    The Natoli AIM™ Pro Plus control system is a flexible software and hardware architecture that is standard on Natoli production tablet presses. This industry-leading package can be retrofitted to almost any production tablet press to increase production, improve tablet consistency, and provide an easier-to-manage production environment.

  6. Single-Station Hydraulic Pharmaceutical Tablet Press: NP-P20A 10/2/2019

    Natoli Engineering’s NP-P20A single-station hydraulic tablet press is a favorite for the production of injectable micropellets and for marginal formulations requiring deep-fill. The NP-P20A meets the FDA’s requirements for batch reporting and secure data management under CFR 21 Part 11 compliance.

  7. R&D Pharmaceutical Tablet Press: NP-RD30 6/5/2018

    Natoli Engineering is quickly becoming the leader in R&D tablet presses with this next-generation rotary tablet press. Designed to help solve formulation and scale-up challenges, the NP-RD30 rotary R&D tablet press replicates the design and functionality of a production press. The turret velocity of the NP-RD30 can reach that of production presses, meaning dwell time can be more accurately established during research and development.

  8. Quick-Release Pharmaceutical Tablet Tooling 6/5/2018

    Natoli Quick-Release Tablet Tooling allows researchers to test different dwell times during the tablet R&D process without the expense of buying several different sets of tools or the time needed to change complete sets of tooling or turret speed.

  9. Pharmaceutical Capsule Filling MRO Parts Accessories 5/15/2018

    Through our Carlisle Precision Encapsulation Parts subsidiary, Natoli Engineering manufactures premium change and spare parts for most major brands of pharmaceutical encapsulation or capsule filling machines.

  10. Natoli AIM™ Data Acquisition & Analytical Software for the NP-RD10A Tablet Press 3/6/2018

    Natoli Engineering now offers AIM™ Data Acquisition & Analytical Software for the Natoli NP-RD10A research and development tablet press. The combination of AIM™ Software and this R&D tablet press enables the researcher to evaluate formulation properties and identify potential tableting issues—including capping, lamination, sticking/picking, and tablet robustness—during the tablet development process. Plus, the software can optimize tablet tensile strength and lubrication for successful large-scale manufacturing production.