The ADC field is in a transitional period. Older approaches to conjugate composition and dosing regimens still dominate the ADC clinical pipeline, but preclinical work is driving a rapid evolution in how we strategize to improve efficacy and reduce toxicity towards better therapeutic outcomes. In an indication of future directions for the field, antibody conjugates bearing non-cytotoxic small molecule payloads are being developed to reduce side effects associated with treatment of chronic diseases.
Bioprocessing development is a long and costly process. Building in continuous characterization and connected bioprocessing cuts timelines and increases the available information through real-time analytics.
Understand the strategies which can be employed at the different stages of development when choosing parenteral dosage forms.
The extensive timeline to develop a drug is due to a multitude of formulation challenges that formulation experts face. When it comes to solving these challenges, there have been significant advancements in drug development techniques to counter these challenges including bioavailability, stability, efficacy, manufacturability, and safety.
Why understanding both the product and every step of the process is crucial in cell and gene therapy production.
Learn how a structured 3-step approach can help overcome the challenge of molecular characterization and a limited budget.
How SYLOID FP silica products contribute significantly in mitigating/resolving key challenges such as formulation stability over time and their ability to withstand challenging processing conditions.
The combined adsorption capacity, porosity, particle size, and density of the SYLOID® XDP silicas provide a tool to convert liquid ingredients into free flowing powder.
Grace’s SYLOID® 244 FP silica is highly porous and an excellent solution for converting viscous Simethicone into compressible free flowing powder to make chewable tablets.
SYLOID® FP and XDP silicas excipients are micronized synthetic amorphous silica gels of high purity which are widely formulated into many pharmaceutical products.
NuAire is pleased to partner with the reputable brand Hitachi Koki to offer our customers sales and support of table top and floor standing Mirco Ultracentrifuges in the North American market.
Our SYLOID® FP silica (silicon dioxide) has been widely used and trusted for decades by the pharmaceutical industry as an excipient and processing aid. The material's unique mesoporosity, adsorptive capacity, density, and greater internal surface area provide advantages over fumed silica (colloidal silicon dioxide) and offer multi-functional benefits to formulators. SYLOID® FP silica grades are engineered to deliver a range of properties and can act as an effective stabilizer, protectant, desiccant, disintegrant, anti-tacking, and/or anti-caking agent. Advanced applications such as oil adsorption, carrier, and liqui-solid can be achieved with SYLOID® XDP silica. Additionally, Grace offers SYLOID® G silica specifically designed for cost effective glidant in generic pharmaceutical formulations. All of Grace's SYLOID® silica products are a synthetic amorphous non-crystalline form.
The VirTis BenchTop Pro freeze dryers have been designed to meet the needs of the most demanding research laboratories. Each system can be configured to meet your present and future needs. Condenser refrigeration packages of -55°C, -75°C, -85°C and -105°C can meet the demands of both aqueous or aqueous-solvent based formulations.
NuAire benchtop centrifuges offer mono and multi functionality, refrigerated and non-refrigerated models. Technical innovations optimize productivity in your laboratory work to improve results, save time, while providing a greater relative centrifugal force (RFC).
The Hitachi Koki model himac CR22N High-Speed Refrigerated Centrifuge offers reliable performance with a maximum RCF of 55,200xg and capacity of 6L for bottles, tubes, or microplates. Patented features such as the Automatic Rotor Identification and Rotor Cover Detector make the CR22N the ideal separation tool for multiple research applications involving DNA, RNA, viruses, proteins, and more
NuAire benchtop centrifuges offer mono and multi functionality, refrigerated and non-refrigerated models. Technical innovations optimize productivity in your laboratory work to improve results, save time, while providing a greater relative centrifugal force (RFC).
The user-friendly Prism™ Mini is a reliable, compact, and economical personal microcentrifuge ideal for quick spins that can be used for a wide range of molecular biology protocols. Prism™ Mini works out of the box with a maintenance-free drive system and advanced design providing quiet operation and proper ventilation protecting temperature-sensitive samples. Prism™ Mini includes two (2) quick release interchangeable rotors with a max speed up to 6000 RPM.
NuAire offers ventilated and refrigerated micro-centrifuges ideal for high and low speed applications for small sample volumes.
