Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
-
![Strategies For API Solubility And Bioavailability Enhancement: Selecting Technologies And Excipients]( "Practical Formulation Strategies For Poorly Soluble APIs")
Practical Formulation Strategies For Poorly Soluble APIsPoor aqueous solubility now defines most drug candidates in development, making early screening and solid-state assessment essential to achieving reliable exposure and avoiding costly reformulation downstream.
-
![The Art of Protein Expression-FutureFields]( "The Art Of Protein Expression: A Guide To Understanding Difficult-To-Express Proteins")
The Art Of Protein Expression: A Guide To Understanding Difficult-To-Express ProteinsProtein expression failures often result from misfolding, PTMs, assembly issues, insolubility, and toxicity. Understanding their interplay can improve yields.
-
![GettyImages-2280454860-scientist-liver-organ-research]( "The Continuing Challenge Of Drug-Induced Liver Injury")
The Continuing Challenge Of Drug-Induced Liver InjuryRecent liver safety concerns highlight the limits of conventional preclinical testing. Human-relevant models could help researchers detect drug-induced liver injury earlier and reduce costly setbacks.
-
![Smart Manufacturing facility-GettyImages-1938951579]( "Safety First: Considerations When Formulating High Potency Compounds")
Safety First: Considerations When Formulating High Potency CompoundsDeveloping highly potent APIs comes with unique challenges. Explore strategies for managing risk, protecting personnel, and advancing programs with confidence.
-
![GettyImages-1585548490-modular-facility-laboratory-drug-development]( "Insights Into Evionnaz's new R&D Center")
Insights Into Evionnaz's new R&D CenterPharmaceutical innovation depends on speed and smarter decisions. Discover how advanced R&D technologies and real-time insights are helping accelerate development.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
-
![GettyImages-1370147753-white-tablets-pill-bottle]( "Formulation And Process Challenges For A Needle-Shaped API")
Formulation And Process Challenges For A Needle-Shaped APIManaging challenging active pharmaceutical ingredient crystal structures and choosing dry granulation over wet granulation requires strategic processing choices.
-
![From Sequence To Scale In Seven Months_Future Fields]( "From Sequence To Scale In Seven Months")
From Sequence To Scale In Seven MonthsAccelerate recombinant protein development from sequence to scale while maintaining stable expression, manufacturing efficiency, and critical quality attributes.
-
![Protein that mutates in the development of cancer-GettyImages-1466537448]( "Characterizing Protein Stability By DSC")
Characterizing Protein Stability By DSCDiscover how differential scanning calorimetry quantifies the thermodynamic forces behind protein folding and stability, providing valuable insight for protein engineering and therapeutic formulation.
-
![GettyImages-2202060913-protein-structure-blue-and-white-3d]( "Life Science Applications Of DSC")
Life Science Applications Of DSCLearn how Differential Scanning Calorimetry directly measures macromolecular stability, unfolding, and binding interactions, providing valuable thermodynamic insights for protein engineering.
-
![GettyImages-1167352850-antibody-green]( "Streamline Antibody Analysis For Faster Protein Characterization")
Streamline Antibody Analysis For Faster Protein CharacterizationStrengthen your antibody characterization. Explore approaches for improving sizing accuracy, resolving heterogeneity, and generating reproducible data across demanding biopharmaceutical workflows.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Standalone instrument with touchscreen and built-in sample ports for small volumes and cuvettes
The SpectraMax® QuickDrop™ Micro-Volume Spectrophotometer quantifies very small amounts of DNA, RNA, oligos, and proteins.
Patch-clamp amplifiers from, whole-cell, and two electrode recordings, single channels to large macroscopic recordings
The Axon Instruments® series of amplifiers provide best-in-class solutions for the entire range of patch-clamp experiments.
In the pharmaceutical industry, every capsule and tablet begins with a concept. Transforming that idea into a tangible product requires an expert manufacturing partner. Natoli stands out as a leader in pharmaceutical equipment and services, providing a comprehensive journey from formulation to full-scale production.
THUNDER Imager Live Cell & 3D Assay
Decode 3D biology in real time*
With THUNDER Imagers you begin every experiment with confidence. They are your solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids.
Research Use Only (RUO) lipid nanoparticle (LNP) reagents to deliver RNA into hematopoietic stem cells (HSCs) for cell and gene therapy applications.
Unexpected downtime can drastically impact your organization’s ability to service customers and hinder innovation. With Waters FlexCHOICE: mySystem Coverage*, you can safeguard against lost productivity and unexpected downtime and spend more time on what matters most – your customers and your research.
When it comes to solid dosage formulations, the most common challenge formulators face is poor solubility. In numbers: 70% of drugs in development are poorly soluble.
Leica DM3000
Enhance Laboratory Workflow
The Leica DM3000 microscopes for pathology, cytology, haematology and many other applications feature a motorized nosepiece, condenser head, automated light intensity adjustment, and optional foot pedal. These intuitive microscopes improve workflows significantly. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).
FORMULATION DEVELOPMENT SOLUTIONS
- Simplify Your Linker-Payload Synthesis
- Gibco Efficient-Pro Medium And Feeds Evaluation Guide
- Leading The Way In Rapid Quantitation Of Host Cell DNA
- API Stability Combined With Rapid Disintegration
- Mass Detection For Undergraduates
- Laboratory Services
- Which Organ-Chip Design Is Right For You?
- Is NSA Sabotaging Your Lab's Productivity
- Trilysine Acetate: Enabling Advanced Surgical, Drug Delivery Tech
- Our Science-Forward Approach To API Development, Manufacturing
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Contec Launches Sterile ReadySAT™ With PeridoxRTU® Sporicidal Wipes For Cleanrooms
- Upperton Unveils New Brand Identity Reflecting Evolution Into Specialist CDMO
- Hovione To Commission World's First ConsiGma® CDC Flex, Bringing Next-Generation Continuous Tableting To The U.S.
- Agilent Expands Oligonucleotide Manufacturing Capabilities With New Boulder Lab
- Flamma Acquires API Manufacturing Site In Padova, Italy
- Bayer Expanding U.S. Pharmaceutical Manufacturing Footprint With New Ohio Manufacturing Facility
- ROSS 600-Gallon ASME Pressure Vessel For High-Pressure Processing
- METTLER TOLEDO Expands Foreign Material Re-Inspection Services With New Dallas Facility
- Serán Bioscience Strengthens Spray Dry Capabilities With Growth Investment From Biospring Partners To Accelerate Commercial Expansion And Meet Surging Customer Demand
- Rottendorf Pharma Is CDMO Leadership Award Winner 2025