Drug Formulation, Formulation Development

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Printing A New Path To The Brain: 3D Buccal Nanofilms For CNS Lymphoma

Engineering Better ADCs, Part 2: Characterization, CMC, And More

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Engineering Better ADCs, Part 1: MoA, Conjugation Chemistry, And More

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4 Ways To Build A Better CMC Tech Transfer

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

Advancing The Development Of Syringe-Device Combinations
Defining the design for syringe-autoinjector pairings early, through shared compatibility testing, can reduce integration risk for high-viscosity biologics intended for self-administration at home.
Nasal Delivery Of Psychedelics: Next Generation Delivery Options
Psychedelic development has moved past regulatory hurdles to a question of formulation and delivery. For fast-acting molecules, dosing control and onset speed are pushing developers toward one route.
Early Automation Integration Reshapes How Drugs Move
Introducing automation during R&D rather than in Phase 3 changes how processes scale. Unified data and standards-based control logic carry across bench, pilot, and commercial stages with less rework.
Why Controlled Release Is Essential For Patient-centric Drug Development
Controlled release design can ease daily dosing burden by moderating swings in drug exposure, though the right approach depends on API properties and what manufacturing can deliver at scale.
Everyday Medicines, Complex Manufacturing: 5 Reasons They Aren't Simple To Make
Tablets and liquid medicines look simple to the patient, but their reliability depends on formulation choices made early and on technical expertise that continues well after commercial production begins.

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

Long-Acting GnRH Antagonist For Advanced Prostate Cancer
Achieve rapid testosterone suppression for 6+ months with a novel low-volume subcutaneous depot formulation, eliminating the initial surge and offering a new approach for advanced prostate cancer treatment.
Why Early Device Decisions Matter: How Immunovant Accelerated Its Program
Deferring autoinjector selection can seem to preserve flexibility, yet it often moves constraints downstream. Integrating the device during Phase IIb changed one program's timeline and removed bridging work.
Using Human-Centered Engineering To Improve HPLC Solvent Handling
Real-world HPLC workflows show how closed-system solvent handling can address contamination, downtime, and waste across laboratory settings.
Reducing Cycle Time By 88% Through Strategic Solvent Replacement In Pharmaceutical Development
Replacing methylene chloride in a slow, labor-intensive API step led to a single-solvent, one-pot process with a shorter reaction time and improved yield and purity.
Improving Stability Through Science-Led OSD Reformulation
A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

HyClone™ Cell Culture Media For Viral Vector Production

Whether you're looking to boost performance, enhance your capabilities, or simply get consistent, high-quality results, HyClone™ peak expression medium and HyClone™ prime expression medium are the solutions for you.

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Unique Confocal Imaging Solutions

Unique confocal imaging solution capable of imaging more than a million wells a week

The ImageXpress® Micro Confocal system is a high-content solution that can switch between widefield and confocal imaging of fixed and live cells.

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Sophisticated Patch-Clamp Electrophysiology Data Acquisition And Analysis Software

Preconfigured protocols and custom assay workflows simplify microplate data acquisition and analysis

SoftMax® Pro Software for Windows 10 is designed to provide the simplicity, flexibility and power required for advanced data analysis. It provides ready-to-run protocols, analysis algorithms, and 21 different curve fit options.

Nasal Dosage Form Development

Upperton have developed UpperNose™, a nasal product development approach designed to streamline the development process for nasal dosage forms.

Ergonomic System Microscopes for Complex Clinical Applications

Leica DM2000 LED - Ergonomic System Microscopes for Complex Clinical Applications

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Lifetime Imaging In An Instant With A FLIM Microscope

STELLARIS 8 FALCON FLIM Microscope

The contrast is clear. Lifetime imaging in an instant.

STELLARIS 8 FALCON (FAst Lifetime CONtrast) is the future of functional imaging. Harness the power of fluorescence lifetime to investigate cellular physiology and explore dynamics in living cells. STELLARIS 8 FALCON is a fully integrated solution for Fluorescence Lifetime Imaging (FLIM) and enables video-rate lifetime imaging acquisition for rapid kinetic studies in live cells.

STELLARIS 8 FALCON adds a new dimension of contrast to your imaging, opening the door to biosensing and tracking of interactions between proteins. FLIM information is now available for all modalities of the STELLARIS 8 system.

Imager For Live Cell & 3D Cell Culture Assays

THUNDER Imager Live Cell & 3D Assay

Decode 3D biology in real time*

With THUNDER Imagers you begin every experiment with confidence. They are your solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids.

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Generate IUPAC Names From Chemical Structures

Get Systematic Chemical Names for Structures, and Produce Structures from Names

ACD/Name generates chemical names according to IUPAC rules, converts chemical names to structures, and easily handles challenging areas of nomenclature.

Generate names for organic; biochemical; and some inorganic, organometallic, and polymer structures
Convert systematic or trivial names to structures

Formulation Development

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

FORMULATION DEVELOPMENT SOLUTIONS

PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS