Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![Doctor holding antibiotic pills-GettyImages-2271436785]( "Keeping Future Manufacturing Options Open During Development")
Keeping Future Manufacturing Options Open During DevelopmentEarly choices affect manufacturing flexibility, tech transfer, and supply chain resilience. Addressing IP and production needs early helps preserve options for commercialization.
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![west_production_102]( "Mechanical Engineering Design Process For Combination Products")
Mechanical Engineering Design Process For Combination ProductsMechanical engineering for combination drug-delivery devices demands more than good design — it requires data-driven risk management from specs through simulation. Learn how a structured phase approach ensures global manufacturing readiness.
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![Labs 173_WestPharm_Direct 113018-143]( "Considerations In Design And Development Of Novel Combination Drug-Delivery Devices")
Considerations In Design And Development Of Novel Combination Drug-Delivery DevicesPoor scoping kills drug delivery device programs before they start. Learn how to define the right problem, assess risk early, and set boundaries that protect your timeline and budget.
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![sustainability-GettyImages-1443569489]( "Beyond PMI: Solvents As A Key To Sustainable Process Design")
Beyond PMI: Solvents As A Key To Sustainable Process DesignDiscover how data-driven solvent selection helps uncover sustainability opportunities, boost efficiency, and enable smarter process optimization decisions.
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![Targeted Gene Therapies, AI-Powered Genomic Analysis-GettyImages-2196602729]( "How Data-Driven Development Is Transforming Phosphoramidites")
How Data-Driven Development Is Transforming PhosphoramiditesHigh-quality phosphoramidites are key to oligonucleotide therapies. Learn how data-driven optimization boosts purity, streamlines manufacturing, speeds scale-up, and supports commercialization.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![Intestinal tract with digestive health-GettyImages-1985026058]( "Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling")
Predicting Food Effects In Oral Drug Delivery Using PBPK ModelingLearn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.
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![GettyImages-163720603 tablet press, OSD]( "Compaction Simulation For Tablet Technology Transfer And Scale-Up")
Compaction Simulation For Tablet Technology Transfer And Scale-UpCompaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.
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![GettyImages-1365580848-ubiquinol-softgel]( "Predicting Softgel Stability And Shelf Life Using Accelerated Modeling")
Predicting Softgel Stability And Shelf Life Using Accelerated ModelingPredict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.
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![White Tablets-GettyImages-172969989]( "Predicting Drug-Loading Limits In Tablet Formulations")
Predicting Drug-Loading Limits In Tablet FormulationsLearn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
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![GettyImages-498013412-laboratory-flask-water-solubility-dropper]( "Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies")
Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement StrategiesIn silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
S APO Greenough Stereo Microscope
Save up to 20% inspection and rework time*
Continuously improving production, keeping defect rates low, and fulfilling customer requests in order to stay competitive can be very challenging. Leica has developed the S9 stereo microscope series to help you cope with these challenges. With this generation of Greenough stereo microscopes operators will be able to reveal details faster as they spend less time having to adjust the microscope.
*compared to the standard industrial stereo microscope S6 from Leica
Access the future of AI microscopy
Subjectivity of analysis and poor reproducibility are key hurdles to be overcome for biological image analysis. Standard segmentation can lead to sub-standard results and require substantial manual curation which is subject to human error.
Leica M60 Routine Stereo Microscopes
Easily inspect, screen, observe or document. Handle your daily inspection or documentation, work confidently, and stay flexible in times of change. The modular stereo microscopes of the M series from Leica are the right choice for an abundant variety of tasks in life sciences and industrial applications.
The M50, M60, and M80 allow operators to see a large sample overview, work comfortably under the microscope, and capture images of important details easily.
Uniquely Ergonomic System Microscopes With Intelligent Automation Leica DM3000 LED
Enhance Laboratory Workflow
The Leica DM3000 LED microscopes for pathology, cytology, haematology and many other applications feature a motorized nosepiece, condenser head, automated light intensity adjustment, and optional foot pedal. These intuitive microscopes improve workflows significantly. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).
- Enables sample recovery
- Avoids dilution effects
- Analyzes samples in a matrix-free environment
- Has minimal buffer constraints
Used Shimadzu X-Ray Diffractometer, model XRD-6000, 220 volt, serial# Q30344800678 CZ
Nanoform’s award-winning Controlled Expansion of Supercritical Solutions (CESS®) technology is a bottom-up nanoparticle engineering approach that enables the creation of API nanoparticles and can unlock the full therapeutic potential of small molecule drugs.
Custom microscopy workstations to meet your advanced imaging needs.
FORMULATION DEVELOPMENT SOLUTIONS
- Potent, Selective Modulators Of Protein Functions
- Resins Selection Guide
- The Digital Suite For Process Lifecycle Intelligence
- Evolve The Future Of Cell Therapy Manufacturing
- Peptide & Oligonucleotide: CDMO Overview
- Picoliter Dispensing Redefined, Now For Single Cells Too
- A CDMO With Oral Solid Dose And Sterile Injectable Expertise
- Controlled Substances
- HyClone™ Prime Expression Medium
- Increase Speed, Sensitivity, And Resolution With UPLC Column Technology
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Amneal's Planned Sterile Facility Creates Opportunity For Aseptic Filling, Isolator, And Automation Suppliers
- Lonza Expands HPAPI Capacity In Visp, Further Supporting Its Position In Payload-Linker Manufacturing
- AustinPx Expands KinetiSol™ Technology Commercial Access Through Thermo Fisher Scientific Collaboration
- Recipharm Invests In U.S. Fill-Finish Infrastructure To Accelerate Biologics Development
- Four Myths About Embedded CMOs, Busted
- Avoiding Recalls: How To Ensure Sterility In Ophthalmic Products
- Veranova Appoints Dr. Bob Huang Vice President And General Manager Of West Deptford Site
- Leica Biosystems And CellCarta Expand Collaborative Companion Diagnostic Development Model To Accelerate Commercialization Globally
- Quotient Sciences Advances AI-Designed Drug Product Into Clinical Development
- ILC Dover Expands Life Sciences Presence With Water For Injection (WFI) And Custom Chemical Solutions