Drug Formulation, Formulation Development

Research And Quality Control, Sterile Feel, Embossed Imprints Visible, Lab Context With Focus On Uniformity-GettyImages-2262066362

Why Early Evaluation Of Process Parameters Matters In OSD Scale-Up

breathe strips, removes smell, kill bacteria and germs-GettyImages-1453051342

Printing A New Path To The Brain: 3D Buccal Nanofilms For CNS Lymphoma

Engineering Better ADCs, Part 2: Characterization, CMC, And More

Antibody-drug-conjugated-with-cytotoxic-payload-Gettyimages-1410189307

Engineering Better ADCs, Part 1: MoA, Conjugation Chemistry, And More

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

A Guide To Bioavailability Enhancement
Many new drug candidates face oral bioavailability challenges. Particle engineering, lipid systems, and inclusion complexes can boost absorption, though patient variability remains a hurdle.
A Strategic Guide For Challenging Early-Phase Molecules
Early formulation decisions for high-viscosity, unstable, and potent molecules impact scale-up, regulatory flexibility, and lifecycle value. Getting them right early helps avoid costly rework.
Advancing The Development Of Syringe-Device Combinations
Defining the design for syringe-autoinjector pairings early, through shared compatibility testing, can reduce integration risk for high-viscosity biologics intended for self-administration at home.
Nasal Delivery Of Psychedelics: Next Generation Delivery Options
Psychedelic development has moved past regulatory hurdles to a question of formulation and delivery. For fast-acting molecules, dosing control and onset speed are pushing developers toward one route.
Early Automation Integration Reshapes How Drugs Move
Introducing automation during R&D rather than in Phase 3 changes how processes scale. Unified data and standards-based control logic carry across bench, pilot, and commercial stages with less rework.

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

Long-Acting GnRH Antagonist For Advanced Prostate Cancer
Achieve rapid testosterone suppression for 6+ months with a novel low-volume subcutaneous depot formulation, eliminating the initial surge and offering a new approach for advanced prostate cancer treatment.
Why Early Device Decisions Matter: How Immunovant Accelerated Its Program
Deferring autoinjector selection can seem to preserve flexibility, yet it often moves constraints downstream. Integrating the device during Phase IIb changed one program's timeline and removed bridging work.
Using Human-Centered Engineering To Improve HPLC Solvent Handling
Real-world HPLC workflows show how closed-system solvent handling can address contamination, downtime, and waste across laboratory settings.
Reducing Cycle Time By 88% Through Strategic Solvent Replacement In Pharmaceutical Development
Replacing methylene chloride in a slow, labor-intensive API step led to a single-solvent, one-pot process with a shorter reaction time and improved yield and purity.
Improving Stability Through Science-Led OSD Reformulation
A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

GLP-1 Receptor Agonist Solutions

The journey of a GLP-1 receptor agonist (GLP-1 RA) molecule is complex.

GettyImages-2193981513-3d-molecular-structure

Patient-Derived Assay-Ready Organoids

Gain human-relevant insights with patient-derived assay-ready organoids.

Mass Spectrometry Software For Spectral Interpretation And Characterization

One MS Software for All Your Mass Spectral Data Analysis and Management

ACD/MS Workbook Suite is an all-in-one package for MS data handling.

Process MS, LC/MS, and GC/MS data acquired with instruments from any major vendor
Auto-annotate peaks and associate them with compound structures
Identify unknowns by deconvoluting spectra and searching databases for spectral matches
Create easily shareable and searchable spectral databases

Our Most Advanced MS Toolset For Structure Characterization

Characterize Samples and Identify Unknown Components

Do you often need to identify unknown compounds from complex samples? ACD/MS Structure ID Suite offers a simple, replicable workflow for generating and narrowing down structural candidates.

Deconvolute complex LC/MS and GC/MS data into individual component traces
Search proprietary and commercial databases for spectral matches
Search PubChem for accurate-mass and molecular-formula matches
Narrow down candidate structures by retention time and fragment include/exclude lists

Enhance Your Workflow With A High-Speed Centrifuge System

Enhance your workflow with the Avanti JXN-26 high-speed Centrifuge System

6.0 L Max Capacity
26,000 RPM
81,770 x g

Multi-Mode Microplate Reader For Assay Flexibility

Precise optics, fluidic transfer, and assay flexibility on one integrated microplate reader.

molecular-devices-pico-imagexpresspicofront-trans

ImageXpress Pico, Digital Microscopy Providing Results In Minutes

Digital microscopy with automated brightfield, fluorescence, and Digital Confocal imaging

The ImageXpress® Pico Automated Cell Imaging System is more than a digital microscope, combining high-resolution imaging with powerful analysis. Whether running fluorescence imaging or brightfield assays, the automated imager features a comprehensive portfolio of preconfigured protocols for cell-based assays to shorten the learning curve, so you can start running experiments quickly.

molecular-devices-pclamp-11-software-suite

Sophisticated Patch-Clamp Electrophysiology Data Acquisition And Analysis Software

Preconfigured protocols and custom assay workflows simplify microplate data acquisition and analysis

SoftMax® Pro Software for Windows 10 is designed to provide the simplicity, flexibility and power required for advanced data analysis. It provides ready-to-run protocols, analysis algorithms, and 21 different curve fit options.

Formulation Development

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

FORMULATION DEVELOPMENT SOLUTIONS

PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS