Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
-
![Strategies For API Solubility And Bioavailability Enhancement: Selecting Technologies And Excipients]( "Practical Formulation Strategies For Poorly Soluble APIs")
Practical Formulation Strategies For Poorly Soluble APIsPoor aqueous solubility now defines most drug candidates in development, making early screening and solid-state assessment essential to achieving reliable exposure and avoiding costly reformulation downstream.
-
![The Art of Protein Expression-FutureFields]( "The Art Of Protein Expression: A Guide To Understanding Difficult-To-Express Proteins")
The Art Of Protein Expression: A Guide To Understanding Difficult-To-Express ProteinsProtein expression failures often result from misfolding, PTMs, assembly issues, insolubility, and toxicity. Understanding their interplay can improve yields.
-
![GettyImages-2280454860-scientist-liver-organ-research]( "The Continuing Challenge Of Drug-Induced Liver Injury")
The Continuing Challenge Of Drug-Induced Liver InjuryRecent liver safety concerns highlight the limits of conventional preclinical testing. Human-relevant models could help researchers detect drug-induced liver injury earlier and reduce costly setbacks.
-
![Smart Manufacturing facility-GettyImages-1938951579]( "Safety First: Considerations When Formulating High Potency Compounds")
Safety First: Considerations When Formulating High Potency CompoundsDeveloping highly potent APIs comes with unique challenges. Explore strategies for managing risk, protecting personnel, and advancing programs with confidence.
-
![GettyImages-1585548490-modular-facility-laboratory-drug-development]( "Insights Into Evionnaz's new R&D Center")
Insights Into Evionnaz's new R&D CenterPharmaceutical innovation depends on speed and smarter decisions. Discover how advanced R&D technologies and real-time insights are helping accelerate development.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
-
![GettyImages-1370147753-white-tablets-pill-bottle]( "Formulation And Process Challenges For A Needle-Shaped API")
Formulation And Process Challenges For A Needle-Shaped APIManaging challenging active pharmaceutical ingredient crystal structures and choosing dry granulation over wet granulation requires strategic processing choices.
-
![From Sequence To Scale In Seven Months_Future Fields]( "From Sequence To Scale In Seven Months")
From Sequence To Scale In Seven MonthsAccelerate recombinant protein development from sequence to scale while maintaining stable expression, manufacturing efficiency, and critical quality attributes.
-
![Protein that mutates in the development of cancer-GettyImages-1466537448]( "Characterizing Protein Stability By DSC")
Characterizing Protein Stability By DSCDiscover how differential scanning calorimetry quantifies the thermodynamic forces behind protein folding and stability, providing valuable insight for protein engineering and therapeutic formulation.
-
![GettyImages-2202060913-protein-structure-blue-and-white-3d]( "Life Science Applications Of DSC")
Life Science Applications Of DSCLearn how Differential Scanning Calorimetry directly measures macromolecular stability, unfolding, and binding interactions, providing valuable thermodynamic insights for protein engineering.
-
![GettyImages-1167352850-antibody-green]( "Streamline Antibody Analysis For Faster Protein Characterization")
Streamline Antibody Analysis For Faster Protein CharacterizationStrengthen your antibody characterization. Explore approaches for improving sizing accuracy, resolving heterogeneity, and generating reproducible data across demanding biopharmaceutical workflows.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Unexpected downtime can drastically impact your organization’s ability to service customers and hinder innovation. With Waters FlexCHOICE: mySystem Coverage*, you can safeguard against lost productivity and unexpected downtime and spend more time on what matters most – your customers and your research.
STELLARIS 5 Cryo Confocal Light Microscope
The STELLARIS 5 Cryo is a confocal light microscope system that helps you to target your area of interest for cryo-electron tomography (CryoET). The STELLARIS 5 Cryo gives you the precision to target reliably, while still offering superior performance you can count on and improved productivity for your experiments.
Our custom expression platform directly addresses the primary host limitations in early-to-mid stage assay development:
Leica M125 C Encoded Stereo Microscopes
Total recall of your settings
Your goal: high-quality images that allow measurements and can be accurately repeated with minimal effort. The Leica coded stereo microscopes help you to pave the way to correct results.
- Coded microscopes consistently deliver calibrated and comparable images
- Reproduce images in moments with the Leica “Store and Recall” function
- Fully apochromatic corrected zoom optics deliver high quality images
- Customize the microscope system to your task with the exclusive range of accessories
Whether you're looking to boost performance, enhance your capabilities, or simply get consistent, high-quality results, HyClone™ peak expression medium and HyClone™ prime expression medium are the solutions for you.
Measure heat flow, weight loss, dimension change, or mechanical properties as a function of temperature.
Patch-clamp amplifiers from, whole-cell, and two electrode recordings, single channels to large macroscopic recordings
The Axon Instruments® series of amplifiers provide best-in-class solutions for the entire range of patch-clamp experiments.
Siegfried is your expert in ophthalmic formulations with outstanding manufacturing and packaging capabilities.
FORMULATION DEVELOPMENT SOLUTIONS
- Drug Product Development And Manufacturing Services
- Liver Bio-Kit
- Custom Organ-Chip Models For A Wide Variety Of Applications
- Culture Module That Sustains The Life Of Cells
- Where Expertise Meets Simplicity: BD PartnerPath™ Program
- Neotame And Sucralose: Two Ways To Ace The Taste Test
- Multiparticulates For Modified Release Systems
- Small Molecule Discovery Network And Capabilities
- High-Throughput Cellular Screening System
- Complete Organ-Chip Solutions To Fast-Track Your Drug Discovery
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Contec Launches Sterile ReadySAT™ With PeridoxRTU® Sporicidal Wipes For Cleanrooms
- Upperton Unveils New Brand Identity Reflecting Evolution Into Specialist CDMO
- Hovione To Commission World's First ConsiGma® CDC Flex, Bringing Next-Generation Continuous Tableting To The U.S.
- Agilent Expands Oligonucleotide Manufacturing Capabilities With New Boulder Lab
- Flamma Acquires API Manufacturing Site In Padova, Italy
- Bayer Expanding U.S. Pharmaceutical Manufacturing Footprint With New Ohio Manufacturing Facility
- ROSS 600-Gallon ASME Pressure Vessel For High-Pressure Processing
- METTLER TOLEDO Expands Foreign Material Re-Inspection Services With New Dallas Facility
- Serán Bioscience Strengthens Spray Dry Capabilities With Growth Investment From Biospring Partners To Accelerate Commercial Expansion And Meet Surging Customer Demand
- Rottendorf Pharma Is CDMO Leadership Award Winner 2025