Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![west_production_102]( "Mechanical Engineering Design Process For Combination Products")
Mechanical Engineering Design Process For Combination ProductsMechanical engineering for combination drug-delivery devices demands more than good design — it requires data-driven risk management from specs through simulation. Learn how a structured phase approach ensures global manufacturing readiness.
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![Labs 173_WestPharm_Direct 113018-143]( "Considerations In Design And Development Of Novel Combination Drug-Delivery Devices")
Considerations In Design And Development Of Novel Combination Drug-Delivery DevicesPoor scoping kills drug delivery device programs before they start. Learn how to define the right problem, assess risk early, and set boundaries that protect your timeline and budget.
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![sustainability-GettyImages-1443569489]( "Beyond PMI: Solvents As A Key To Sustainable Process Design")
Beyond PMI: Solvents As A Key To Sustainable Process DesignDiscover how data-driven solvent selection helps uncover sustainability opportunities, boost efficiency, and enable smarter process optimization decisions.
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![Targeted Gene Therapies, AI-Powered Genomic Analysis-GettyImages-2196602729]( "How Data-Driven Development Is Transforming Phosphoramidites")
How Data-Driven Development Is Transforming PhosphoramiditesHigh-quality phosphoramidites are key to oligonucleotide therapies. Learn how data-driven optimization boosts purity, streamlines manufacturing, speeds scale-up, and supports commercialization.
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![pharma-partners-GettyImages-2182052451]( "Three Keys To E&L Success: Study Design, Partner Selection, And Timing")
Three Keys To E&L Success: Study Design, Partner Selection, And TimingSuccessful E&L planning starts before testing begins. Aligning study design, partner expertise, and timing helps teams focus on the right risks, avoid surprises, and support stronger development.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![Intestinal tract with digestive health-GettyImages-1985026058]( "Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling")
Predicting Food Effects In Oral Drug Delivery Using PBPK ModelingLearn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.
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![GettyImages-163720603 tablet press, OSD]( "Compaction Simulation For Tablet Technology Transfer And Scale-Up")
Compaction Simulation For Tablet Technology Transfer And Scale-UpCompaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.
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![GettyImages-1365580848-ubiquinol-softgel]( "Predicting Softgel Stability And Shelf Life Using Accelerated Modeling")
Predicting Softgel Stability And Shelf Life Using Accelerated ModelingPredict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.
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![White Tablets-GettyImages-172969989]( "Predicting Drug-Loading Limits In Tablet Formulations")
Predicting Drug-Loading Limits In Tablet FormulationsLearn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
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![GettyImages-498013412-laboratory-flask-water-solubility-dropper]( "Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies")
Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement StrategiesIn silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Observe the viability of your cells with the field-upgradeable cellular imaging option for the SpectraMax i3/i3x Multi-mode Detection Platform.
Research Use Only (RUO) lipid nanoparticle (LNP) reagents to deliver RNA into hematopoietic stem cells (HSCs) for cell and gene therapy applications.
Microscope Camera K3C
For Life Science and Industry Imaging Applications and Analysis
The K3C color and K3M monochrome cameras are your solutions for fast and reliable analytical tasks typically done for life science, industrial, and clinical applications. These cameras empower you to image a vast range of challenging samples with color-brightfield and fluorescence microscopy. Examples include fluorescently labeled and stained tissues and cells, particles for cleanliness analysis, steel, and forensic evidence.
We have developed an innovative portfolio of affinity chromatography resins to help you solve challenges in the downstream process of next-generation antibody therapeutics. These resins are specifically designed for the purification of engineered monoclonal antibody (mAbs) modalities.
Uniquely Ergonomic System Microscopes With Intelligent Automation Leica DM3000 LED
Enhance Laboratory Workflow
The Leica DM3000 LED microscopes for pathology, cytology, haematology and many other applications feature a motorized nosepiece, condenser head, automated light intensity adjustment, and optional foot pedal. These intuitive microscopes improve workflows significantly. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).
Whether you're looking to boost performance, enhance your capabilities, or simply get consistent, high-quality results, HyClone™ peak expression medium and HyClone™ prime expression medium are the solutions for you.
Developing an optimized formulation tailored to your API nanoparticles is critical to unlocking their full potential.
Gene therapies hold immense potential to provide long-lasting treatments for a wide range of diseases. At Cytiva, we offer GMP-compliant, end-to-end manufacturing solutions designed to support the development and commercialization of advanced medicines across multiple modalities – including AAV, adenovirus (AV), lentivirus (LV), plasmid DNA (pDNA) and exosomes. Our dependable suite of technologies and expertise ensures scalability, quality, and regulatory confidence at every stage of your journey.
FORMULATION DEVELOPMENT SOLUTIONS
- From Process Development To QC—Optimize Your mAbs Workflow
- Peptide CDMO Services
- Steroids: Development And Manufacturing
- Chip-R1™ Basic Research Kit
- Are You In Control Of Your Protein Galactosylation Profile?
- Curia R&D Pipeline Overview
- Reliable RNA And cfDNA Results Begin With Cleaner Reagents
- Adare Pharma Solutions (APS) Orbis Overview
- Contract Manufacturing Solutions For Drug Delivery Systems
- Increased Productivity Powered By An Automation Workstation
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Amneal's Planned Sterile Facility Creates Opportunity For Aseptic Filling, Isolator, And Automation Suppliers
- Lonza Expands HPAPI Capacity In Visp, Further Supporting Its Position In Payload-Linker Manufacturing
- AustinPx Expands KinetiSol™ Technology Commercial Access Through Thermo Fisher Scientific Collaboration
- Recipharm Invests In U.S. Fill-Finish Infrastructure To Accelerate Biologics Development
- Four Myths About Embedded CMOs, Busted
- Avoiding Recalls: How To Ensure Sterility In Ophthalmic Products
- Veranova Appoints Dr. Bob Huang Vice President And General Manager Of West Deptford Site
- Leica Biosystems And CellCarta Expand Collaborative Companion Diagnostic Development Model To Accelerate Commercialization Globally
- Quotient Sciences Advances AI-Designed Drug Product Into Clinical Development
- ILC Dover Expands Life Sciences Presence With Water For Injection (WFI) And Custom Chemical Solutions