Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![GettyImages-1294339667-scientists-protective-gear-tablet-teamwork]( "Nitrosamine Risk Management: Your Questions Answered")
Nitrosamine Risk Management: Your Questions AnsweredNavigate nitrosamine impurities with early risk assessments, trace-level analytical testing, and careful excipient evaluation. Learn strategies to strengthen compliance and optimize testing programs.
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![GettyImages-1407655244-dry-podwer-injectable-injector]( "Advancing Reconstitutable Injectables: Aseptic Powder Filling & Dual Chamber Delivery")
Advancing Reconstitutable Injectables: Aseptic Powder Filling & Dual Chamber DeliverySpray-dried powders, gravimetric filling, and dual-chamber syringes are converging into one development pathway for reconstitutable injectables, raising the question of how formulation, filling accuracy, and device design should be evaluated together.
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![science laboratory research, healthcare innovation, development, investigation-GettyImages-1751659695]( "Choosing The Right Solid Form")
Choosing The Right Solid FormMastering polymorph screening helps prevent costly reformulation delays. Explore phase-appropriate strategies, experimental methods, and structural informatics for crystal form selection.
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![Blood diagnostics, laboratory testing, disease biomarkers, medical technology-GettyImages-2218591456]( "From Biomarker Data To Proof Of Mechanism")
From Biomarker Data To Proof Of MechanismBiomarker values support mechanism only when the decision, analytical plan, and validation are designed as one chain, with expected direction of change and baseline noise defined before sampling.
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![trialkit-api-GettyImages-2223712653]( "Difficult-To-Purify And Difficult-To-Filter Small Molecules")
Difficult-To-Purify And Difficult-To-Filter Small MoleculesPoor filterability and stubborn impurities often trace back to the same molecular features, which changes how development teams approach scale-up for larger, structurally complex small molecules.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![GettyImages-2190227480-laboratory-scientists-computer-equipment-research]( "Building Confidence In Combination Product Development")
Building Confidence In Combination Product DevelopmentEarly compatibility testing with realistic placebo models helps mitigate formulation risks, ensuring accurate dosing, predictable injection times, and long-term stability.
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![partnership or agreement in the pharmaceutical industry-GettyImages-2173667078]( "From Early Development To Commercial Launch: An End-To-End Partnership")
From Early Development To Commercial Launch: An End-To-End PartnershipBringing a critical therapy to market takes early coordination. See how strategic planning helped accelerate an oncology therapy from clinical development to patients.
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![pharmacology, chemistry, micropipette, biotechnology, Liquid Chromatography-GettyImages-1494345439]( "Selecting The Right Chromatography Strategy")
Selecting The Right Chromatography StrategyDifficult small molecule purifications rarely yield to one technique. Modeling, fraction mapping, and preparative HPLC each solve a different problem, and the right choice depends on the molecule.
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![GettyImages-1052204504-crystallization]( "Optimizing Particle Properties For Difficult Small Molecules")
Optimizing Particle Properties For Difficult Small MoleculesCrystal morphology and unexpected solid-state intermediates often decide whether a difficult small molecule filters, dries, and scales. Thermodynamic stability may not be the right target.
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![science laboratory research, healthcare innovation, development, investigation-GettyImages-1751659695]( "Turning A \"Brick Dust\" Compound Into A Clinically Viable Oral Formulation")
Turning A "Brick Dust" Compound Into A Clinically Viable Oral FormulationAdvanced wet milling and particle stabilization improve solubility, enhance bioavailability, and support scalable manufacturing for complex oral drug development programs.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Platform of automated, single-use systems for tangential flow filtration at multiple scales.
Leica DM300
For slightly more advanced students in biology or 2-4 year college life science classrooms, the Leica DM300 compound microscope is compact, maintenance-free and easy to use to provide trouble free operation each day.
Equipped with a mechanical stage to accommodate two specimen slides and labelled Abbe condenser, the DM300 can be configured with rotatable monocular or binocular tubes for shared viewing and easy storage. Trinocular tube is also possible to go digital.
With 165 years of microscope design and manufacturing experience, the Leica DM300 student microscope provides students with the capabilities they need to study the finest details in all the Life Sciences.
Evaluating small and large molecule therapeutics within cellular environments is essential to understanding their efficacy, potency, and safety within a complex biological system.
The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling the characterization of behaviors during storage, dispensing, processing, and end-use.
Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.
With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.
The Thermo Scientific™ DXR3 Flex Raman Spectrometer is a research-grade Raman spectrometer specifically designed for integration with other analytical techniques.
Find the missing links
The modular DMi8 inverted microscope is the heart of the DMi8 S platform solution. For routine to live cell research, the DMi8 S platform is a complete solution. Whether you need to precisely follow the development of a single cell in a dish, screen through multiple assays, obtain single molecule resolution, or tease out behaviors of complex processes, a DMi8 S system will enable you to see more, see faster, and find the hidden.
- See more – Increase your viewing area up to 10,000x
- See faster – Experiments up to 5x faster
- See the hidden – Activate, ablate, and bleach within one experiment
STELLARIS 8 FALCON FLIM Microscope
The contrast is clear. Lifetime imaging in an instant.
STELLARIS 8 FALCON (FAst Lifetime CONtrast) is the future of functional imaging. Harness the power of fluorescence lifetime to investigate cellular physiology and explore dynamics in living cells. STELLARIS 8 FALCON is a fully integrated solution for Fluorescence Lifetime Imaging (FLIM) and enables video-rate lifetime imaging acquisition for rapid kinetic studies in live cells.
STELLARIS 8 FALCON adds a new dimension of contrast to your imaging, opening the door to biosensing and tracking of interactions between proteins. FLIM information is now available for all modalities of the STELLARIS 8 system.
FORMULATION DEVELOPMENT SOLUTIONS
- Morpho: Alfasigma Contract Development & Manufacturing
- Robust Methods With Fewer Injections
- Neotame And Sucralose: Two Ways To Ace The Taste Test
- Dedicated To Development: Bend, Oregon's Impact
- Contract Manufacturing Solutions For Drug Delivery Systems
- Dynamic And Ergonomic Oligosynthesis Column
- Simplify Your Single Cell Workflow Like Never Before
- Solutions For Aggregate And Fragment Analyses
- Potent, Selective Modulators Of Protein Functions
- Granulated Materials: Easy Handling For Improved Process Efficiency
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Lonza Signs Agreement To Acquire US CDMO Network From Merck KGaA, Darmstadt, Germany, And Significantly Expands Its US Presence
- Bracco To Build New Injectable Drug Manufacturing Facility In North Carolina
- Lonza Further Expands Bioconjugation Manufacturing To Support Growing ADC Demand
- ROSS Portable High Shear Mixing System
- Ardena Launches Online Biomarker Catalogue: 228 Markers, One Quote Request
- Meissner Hosts Ribbon Cutting Ceremony For X-Ray Irradiation Services And Breaks Ground On Phase 2 Of Its Athens, Georgia, U.S.A. Campus
- Global Pharma Manufacturing Community Meets In Berlin For PHARMAP 2027
- LGM Pharma Acquires Sannova Analytical, Expanding cGMP Analytical And GLP Bioanalytical Services
- MVIC And Upperton Pharma Solutions Announce Strategic Collaboration
- All-In-One Solution For Continuous Microbial Monitoring Without Production Interruptions