Formulation Development

Improve precision in ADME and Toxicology applications with a low-drug-absorption profile.

Designed for today’s assays and tomorrow’s breakthroughs—flexible detection that evolves with your science.

The SpectraMax® iD3s and iD5e Multi-Mode Microplate Readers deliver flexible, scalable solutions for absorbance, fluorescence, and luminescence assays—with advanced capabilities for evolving research needs. The iD3s reader offers a streamlined, affordable platform with a tunable monochromator and temperature control, while the iD5e reader adds enhanced detection modes including time-resolved fluorescence (TRF) and tunable fluorescence polarization (FP) and can be expanded to include TR-FRET, HTRF, BRET and western blot. Both readers support on board fluidics with optional dual injectors.

Enhance your workflow with the Avanti JXN-26 high-speed Centrifuge System

• 6.0 L Max Capacity
• 26,000 RPM
• 81,770 x g

GO BEYOND with the SCIEX 7500 system, high performance triple quadrupole LC-MS/MS mass spectrometer

Enter a new era of sensitivity and LC-MS/MS innovation with the SCIEX 7500 system. GO BEYOND current limits of sensitivity, productivity targets, ruggedness and robustness challenges. Pioneer new discoveries with this innovation.

Understand Your Biotransformation Data

MetaSense helps you make sense of all your metabolite identification (MetID) data. Move beyond complex workflows that have you flipping back and forth between a dozen programs.

With a single interface for prediction, data analysis, and knowledge dashboards, make data-driven decisions swiftly.

• Collect all your MetID data and view it in one place
• Auto-generate biotransformation maps and kinetic plots
• Click between interactively linked maps and plots to see your data at any depth
• Reprocess data directly from MetaSense
• Draw conclusions about a drug candidate’s metabolism and viability

When it comes to solid dosage formulations, the most common challenge formulators face is poor solubility. In numbers: 70% of drugs in development are poorly soluble.

Multicolor Multiphoton gets you closer to the truth

The combination of multiple distinct fluorescent labels is increasingly used to study dynamic interaction and spatial relationships among cells and molecules. The goal is to understand a myriad of complex biological events, such as cellular connectivity, cell phenotyping, protein interaction or co-expression, and co-localization. Scaling up such studies to whole organs or tissues requires suitable large-volume multicolor microscopy methods. DIVE and STELLARIS have now merged to provide you with the power of flexible multicolor multiphoton imaging. Furthermore, you can expand the potential of your experiments with additional label-free imaging capabilities.

Seamlessly integrated into the confocal software interface, STELLARIS 8 DIVE multiphoton microscope offers the benefits of high speed and excellent navigation so that dynamic processes in complex samples can be studied with ease. STELLARIS 8 DIVE – A rainbow of possibilities for your research.

Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.

With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.