Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![GettyImages-1441786721 antibodies]( "Cracking Complexity: Leveraging Lessons Learned For Future Bispecific Development")
Cracking Complexity: Leveraging Lessons Learned For Future Bispecific DevelopmentThe shift from static platforms to adaptive, knowledge-driven development helps biopharma teams manage BsAb complexity, accelerate analytical, purification, and formulation development, and improve IND readiness.
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![Scientists in biotechnology Lab-GettyImages-2238689737]( "Getting Breakthrough Biotechnologies To Market")
Getting Breakthrough Biotechnologies To MarketBiotechnology moves quickly, and successful innovation depends on more than breakthrough science. Learn how adaptable strategies can help teams connect emerging tools and manage uncertainty.
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![GettyImages-2178829362-glp-1-protein-3d-render]( "Therapeutic Peptides: Challenges And Solutions For Drug Developers")
Therapeutic Peptides: Challenges And Solutions For Drug DevelopersTherapeutic peptide manufacturing depends on more than synthesis. Discover approaches for verifying raw materials, detecting difficult impurities, and confirming complex sequences with confidence.
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![jim_800x533px-2]( "Ushering In A New Era Of Human-Relevant Drug Discovery")
Ushering In A New Era Of Human-Relevant Drug DiscoveryWith most drug candidates failing before approval, researchers need better ways to predict human responses. Gain insight into how advances in human-relevant modeling are helping improve decisions.
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![Telemedicine, human Uterus recovery-GettyImages-1397378174]( "How Organ-Chips Are Transforming Women's Reproductive Health Research")
How Organ-Chips Are Transforming Women's Reproductive Health ResearchTraditional models often fall short in women’s health research. Learn how human-relevant Organ-Chip systems are providing new ways to study vaginal, cervical, and uterine biology.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![cell engineering, cell programming-GettyImages-1429299555]( "Evaluating Clone Performance And Cell-Specific Productivity")
Evaluating Clone Performance And Cell-Specific ProductivitySee how continuous process monitoring and automated at-line analytics support confident CHO clone ranking, consistent cultivation, and scale-up by connecting pH, viable cell density, and more.
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![GettyImages-2187764040-cell-culture-testing-manufacturing-in-lab]( "A Comparison To Traditional Clone Screening Platforms")
A Comparison To Traditional Clone Screening PlatformsSee how 46 CHO clones performed across automated, deep-well, and microbioreactor fed-batch cultures, using cell density, viability, and IgG concentration to evaluate clone performance.
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![GettyImages-1480549690-nurse-giving-medicine-to-children]( "A Sensory Panel Study With The Focus On High-Intensity Sweeteners")
A Sensory Panel Study With The Focus On High-Intensity SweetenersGain insight into the sensory performance of five high-intensity sweeteners in a simulated bitter formulation, including their effects on sweetness, bitterness, aftertaste, and covering ability.
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![GettyImages-1295693748-mRNA-strand]( "Characterizing mRNA Using Ion-Pairing Reversed-Phase LC/MS")
Characterizing mRNA Using Ion-Pairing Reversed-Phase LC/MSmRNA poly(A) tail analysis depends on targeted digestion, clean LC/MS conditions, and reliable deconvolution. See how RNase 4 digestion and optimized ion-pairing methods support reproducible results.
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![GettyImages-2176324258-chromatography-glp-1-analysis]( "Effect Of Column Chemistry On The Separation Of GLP-1 Peptides")
Effect Of Column Chemistry On The Separation Of GLP-1 PeptidesSmall changes in mobile phase, temperature, and column chemistry can affect the detection of GLP-1 peptide impurities. Learn which conditions improve resolution for challenging peptide analyses.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Gene therapies hold immense potential to provide long-lasting treatments for a wide range of diseases. At Cytiva, we offer GMP-compliant, end-to-end manufacturing solutions designed to support the development and commercialization of advanced medicines across multiple modalities – including AAV, adenovirus (AV), lentivirus (LV), plasmid DNA (pDNA) and exosomes. Our dependable suite of technologies and expertise ensures scalability, quality, and regulatory confidence at every stage of your journey.
Evaluating small and large molecule therapeutics within cellular environments is essential to understanding their efficacy, potency, and safety within a complex biological system.
Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.
With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.
Measure heat flow, weight loss, dimension change, or mechanical properties as a function of temperature.
ÄKTA ready™ chromatography system 450 is a single-use liquid chromatography system.
Characterize Samples and Identify Unknown Components
Do you often need to identify unknown compounds from complex samples? ACD/MS Structure ID Suite offers a simple, replicable workflow for generating and narrowing down structural candidates.
- Deconvolute complex LC/MS and GC/MS data into individual component traces
- Search proprietary and commercial databases for spectral matches
- Search PubChem for accurate-mass and molecular-formula matches
- Narrow down candidate structures by retention time and fragment include/exclude lists
See More with Microflow LC-MS
The M5 MicroLC system is the perfect balance of sensitivity and robustness—more sensitive than traditional analytical flow LC, and more flexible and more robust than nanoflow LC — giving you the potential to optimize your critical workflows, today and into the future.
Gain human-relevant insights with patient-derived assay-ready organoids.
FORMULATION DEVELOPMENT SOLUTIONS
- Small Molecule Drug Substance
- Magnetic Mixer System
- MaxPeak Premier Columns For Intact And Subunit Protein Analysis
- Cell Culture Media For Viral Vector Production
- Preparative Chromatography System Intended For Method And Process Development
- Predict And Assign Fragment Ions
- A Revolutionary Consumable Empowering High-Throughput Organ-Chip Studies
- High Potency API Development And Manufacturing
- Rapid Sterility Testing: Actionable Results In Less Than 5 Hours
- The Digital Suite For Process Lifecycle Intelligence
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- METTLER TOLEDO Introduces LightningBuild Program For Four-Week Delivery
- Project Farma Acquires SimoTech To Expand Life Sciences Manufacturing Services
- Bristol Myers Squibb Selects Houston For Major $2.3B Manufacturing Investment
- Harro Höfliger Expands European Footprint With New France Subsidiary
- ILC Dover Introduces EZJetFlo™ Technology To Transform Powder Dissolution And Mixing In Biopharmaceutical Manufacturing
- STERIS To Invest $600 Million To Build Center Of Excellence In North Carolina
- BeOne Committing $1 Billion+ To U.S. Drug Manufacturing Growth
- Why GSK Is Investing £400 Million In Cambridge
- Virtual Pharma Expo Launches Searchable Six-Year Equipment Demo Archive Ahead Of September Solid Dosage Event
- ROSS 250-Gallon Retention Mixers Designed For High-Pressure Processing