Formulation Development

Calculators & Predictors for LogP, LogD, pK_a, Aqueous Solubility, and more…

The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.

ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.

• Predict aqueous solubility,^* boiling point, logD,^* logP,^* pK_a,^* Sigma, and other molecular descriptors for organic compounds, from structure
• Evaluate the calculated results with sorting, plotting tools
• Assess the reliability of predicted physicochemical property values
• Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
• Train predictors with experimental data to better reflect novel chemical space
• Include custom models and in-house prediction algorithms

^*Models are trainable with experimental data

The Intabio ZT system couples icIEF separation and UV detection with high resolution mass spectrometry on the ZenoTOF 7600 system.

Leica DM300

For slightly more advanced students in biology or 2-4 year college life science classrooms, the Leica DM300 compound microscope is compact, maintenance-free and easy to use to provide trouble free operation each day.

Equipped with a mechanical stage to accommodate two specimen slides and labelled Abbe condenser, the DM300 can be configured with rotatable monocular or binocular tubes for shared viewing and easy storage. Trinocular tube is also possible to go digital.

With 165 years of microscope design and manufacturing experience, the Leica DM300 student microscope provides students with the capabilities they need to study the finest details in all the Life Sciences.

Flow cytometry is a powerful and versatile technique to analyze the physical and chemical characteristics of cells or particles.

With high-performance optics and ergonomic design, the Leica DM IL LED is ideal for cell culture, micromanipulation, documentation of immunostained specimens, and routine live cell examinations.

The Leica DM IL LED features a comprehensive set of contrast methods to monitor your specimen the way you need. High-quality Phase contrast, excellent modulation contrast and brilliant fluorescence are just one fingertip away. Robust stability, plenty of space to work with tools, long working distances to accommodate large culture flasks and a stable illumination without heat make work at the microscope easy and convenient.

For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) including in-vitro-fertilization (IVF).

Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels due to inadequate insulin production or impaired insulin utilization, commonly known as insulin resistance.

Integrated drug discovery greatly benefits programs by blending various scientific disciplines into a unified team focused on your project.

Leica DM2000

With their sophisticated modular design and high-performance fluorescence, the Leica DM2000 microscopes are ideal for complex tasks in pathology, cytology, and many other applications. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).