Formulation Development

Practical Formulation Strategies For Poorly Soluble APIs

Poor aqueous solubility now defines most drug candidates in development, making early screening and solid-state assessment essential to achieving reliable exposure and avoiding costly reformulation downstream.

The Art Of Protein Expression: A Guide To Understanding Difficult-To-Express Proteins

Protein expression failures often result from misfolding, PTMs, assembly issues, insolubility, and toxicity. Understanding their interplay can improve yields.

The Continuing Challenge Of Drug-Induced Liver Injury

Recent liver safety concerns highlight the limits of conventional preclinical testing. Human-relevant models could help researchers detect drug-induced liver injury earlier and reduce costly setbacks.

Safety First: Considerations When Formulating High Potency Compounds

Developing highly potent APIs comes with unique challenges. Explore strategies for managing risk, protecting personnel, and advancing programs with confidence.

Insights Into Evionnaz's new R&D Center

Pharmaceutical innovation depends on speed and smarter decisions. Discover how advanced R&D technologies and real-time insights are helping accelerate development.

Formulation And Process Challenges For A Needle-Shaped API

Managing challenging active pharmaceutical ingredient crystal structures and choosing dry granulation over wet granulation requires strategic processing choices.

From Sequence To Scale In Seven Months

Accelerate recombinant protein development from sequence to scale while maintaining stable expression, manufacturing efficiency, and critical quality attributes.

Characterizing Protein Stability By DSC

Discover how differential scanning calorimetry quantifies the thermodynamic forces behind protein folding and stability, providing valuable insight for protein engineering and therapeutic formulation.

Life Science Applications Of DSC

Learn how Differential Scanning Calorimetry directly measures macromolecular stability, unfolding, and binding interactions, providing valuable thermodynamic insights for protein engineering.

Streamline Antibody Analysis For Faster Protein Characterization

Strengthen your antibody characterization. Explore approaches for improving sizing accuracy, resolving heterogeneity, and generating reproducible data across demanding biopharmaceutical workflows.