Formulation Development

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

  • Insight Driven Formulations
    Insight Driven Formulations

    This whitepaper describes how deploying such a platform can provide end-to-end visibility across Pre-formulations and Formulations Development and expedite the identification and progression of safe, efficacious formulations.

  • Porosity And Its Influence On Pharmaceutical Tablet Dissolution Profiles
    Porosity And Its Influence On Pharmaceutical Tablet Dissolution Profiles

    Drug delivery as solid dosage forms is complex with a number of factors that can noticeably influence their therapeutic benefit. The drug must be stabilized in the tablet and at the same time be available for absorption in a short time after dosing [1]. The formulation and design of soluble oral tablets needs several factors to be considered.

  • Materials Characterization In Pharma
    Materials Characterization In Pharma

    R&D spending in the pharmaceutical industry through 2015 was valued at around $58bn as organisations vied to gain a competitive advantage by bringing new drugs to market as quickly as possible. Materials science is now helping pharmaceutical companies to standardize and control areas such as drug form and manufacture to deliver new products more quickly and with greater quality. The pharma industry is increasingly embracing the principles of Quality by Design (QbD) to improve efficiency and ensure good quality and reduced variability throughout the drug production process.

  • Getting Ready For Phase 1 In Pharmaceutical Development
    Getting Ready For Phase 1 In Pharmaceutical Development

    At the early stages of product development, pharmaceutical development scientists are under increasing time pressure to select the right molecule form, the right formulation and the right final dose form.

  • Integrate Pharma Development For Commercialization Of Novel Therapeutics
    Integrate Pharma Development For Commercialization Of Novel Therapeutics

    This whitepaper introduces the concept of the electronic Development Record (eDR) and how it can propel the development process forwards, reduce costs, and improve quality.

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FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

  • Fighting The Opioid Epidemic: How Grünenthal’s Abuse-Deterrent Technology Contributes
    Fighting The Opioid Epidemic: How Grünenthal’s Abuse-Deterrent Technology Contributes

    While the wider use of opioids has led to many benefits for patients in pain, it also has led to higher incidences of misuse, abuse, and development of opioid addiction. To address this issue without preventing legitimate patients from receiving their necessary medication, Grünenthal set out to create an abuse-deterrent formulation with a technology that creates a physico-chemical barrier to abuse and, as a result, safeguards patients from the battle of addiction.

  • Pharmaceutical Ointment Viscosity Comparisons
    Pharmaceutical Ointment Viscosity Comparisons

    Use technology to achieve desired product performance.

  • Texture Analysis: Comparison Of Moisturizing Cream By Back Extrusion
    Texture Analysis: Comparison Of Moisturizing Cream By Back Extrusion

    Moisturizing creams will be defined by their viscosity or thickness. Formulating moisturizing creams depends on the required end product consistency, influencing the choice of material to use.

  • Meeting US Pharmacopeia Standards For Triethyl Citrate
    Meeting US Pharmacopeia Standards For Triethyl Citrate

    Anton Paar's Generation M density meters and Abbemat refractometers deliver accurate and repeatable measurement results while providing system security for 21 CFR Part 11 compliance.

  • True Scientific Knowledge Management In R&D: Electronic Laboratory Notebooks (ELNs)
    True Scientific Knowledge Management In R&D: Electronic Laboratory Notebooks (ELNs)

    One tool holds a unique position among R&D informatics systems. Unlike other systems, electronic laboratory notebooks (ELNs) both produce data and consume information. An ELN’s ability to capture data, observations, experiences, and context is particularly powerful when combined with other data pipelining tools. The ability to link key pieces of data and mine experiments captured in the ELN for insights fuels true scientific knowledge management. This use case describes the broad organizational benefits that BIOVIA Workbook made possible for a global pharmaceutical company, highlighting how the system is supporting efforts to gain predictive control over key processes in Research and Development.

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FORMULATION DEVELOPMENT PRODUCTS & SERVICES

Benchtop Centrifuges Benchtop Centrifuges

NuAire benchtop centrifuges offer mono and multi functionality, refrigerated and non-refrigerated models. Technical innovations optimize productivity in your laboratory work to improve results, save time, while providing a greater relative centrifugal force (RFC).

High-Speed Refrigerated Centrifuge High-Speed Refrigerated Centrifuge

The Hitachi Koki model himac CR22N High-Speed Refrigerated Centrifuge offers reliable performance with a maximum RCF of 55,200xg and capacity of 6L for bottles, tubes, or microplates. Patented features such as the Automatic Rotor Identification and Rotor Cover Detector make the CR22N the ideal separation tool for multiple research applications involving DNA, RNA, viruses, proteins, and more

Ultracentrifuge Ultracentrifuge

The CP100WX is a general-purpose Ultracentrifuge with outstanding performance up to 100,000 rpm assisting in a wide range of separation protocols in involving proteins, DNA, RNA, metal nano-colloids, and more. Reliable and efficient the Hitachi CP100WX features a Rotor Life Management (RLM) system to automatically maintain rotor logging history maximizing rotor life.

Micro Ultracentrifuges Micro Ultracentrifuges

NuAire is pleased to partner with the reputable brand Hitachi Koki to offer our customers sales and support of table top and floor standing Mirco Ultracentrifuges in the North American market.

Microcentrifuge Microcentrifuge

NuAire offers ventilated and refrigerated micro-centrifuges ideal for high and low speed applications for small sample volumes.

Mini Microcentrifuge  - Prism™ LN-C1801 Mini Microcentrifuge - Prism™ LN-C1801

The user-friendly Prism™ Mini is a reliable, compact, and economical personal microcentrifuge ideal for quick spins that can be used for a wide range of molecular biology protocols. Prism™ Mini works out of the box with a maintenance-free drive system and advanced design providing quiet operation and proper ventilation protecting temperature-sensitive samples. Prism™ Mini includes two (2) quick release interchangeable rotors with a max speed up to 6000 RPM.

Laboratory Centrifuges Laboratory Centrifuges

NuAire benchtop centrifuges offer mono and multi functionality, refrigerated and non-refrigerated models. Technical innovations optimize productivity in your laboratory work to improve results, save time, while providing a greater relative centrifugal force (RFC).

VirTis BenchTop Pro Freeze Dryer with Omnitronics VirTis BenchTop Pro Freeze Dryer with Omnitronics

The VirTis BenchTop Pro freeze dryers have been designed to meet the needs of the most demanding research laboratories. Each system can be configured to meet your present and future needs. Condenser refrigeration packages of -55°C, -75°C, -85°C and -105°C can meet the demands of both aqueous or aqueous-solvent based formulations.

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