Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![GettyImages-2238837244-compliance-meeting-regulation-regulatory]( "Why CMC Continuity Is The Missing Link Between Development And Manufacturing")
Why CMC Continuity Is The Missing Link Between Development And ManufacturingDiscover why CMC continuity is the missing link between development and manufacturing, and how preserving connected product and process knowledge helps reduce handoff risk, accelerate tech transfer, and strengthen manufacturing readiness.
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![paediatric-oral-dose-GettyImages-2251563567]( "Analytical Method Development For Paediatric Oral Dose Products")
Analytical Method Development For Paediatric Oral Dose ProductsThis article explores the key formulation and analytical challenges that pharmaceutical companies face when creating safe, effective, and age-appropriate treatments for paediatric populations.
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![Solubility And Improved Patient Outcomes-GettyImages-2277363545]( "Solubility And Improved Patient Outcomes")
Solubility And Improved Patient OutcomesPoor solubility poses major development challenges. Innovative formulation technologies and careful excipient selection can improve bioavailability and product performance.
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![GettyImages-1417391937-pharmaceutical-spray-drying-with-scientists]( "Overcoming The Obstacles Of Spray-Dried Dispersion Scale-Up")
Overcoming The Obstacles Of Spray-Dried Dispersion Scale-UpSDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.
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![iStock-1248627316-chemistry-beaker-lab-science-experiment]( "Chemoenzymatic N-glycan Conjugation Of Native mAbs Provides Homogeneous, Efficacious ADCs")
Chemoenzymatic N-glycan Conjugation Of Native mAbs Provides Homogeneous, Efficacious ADCsA chemoenzymatic two-stage protocol enables DAR2 ADCs from native, non-engineered mAbs via glycan remodeling at Asn-297 and copper-free click chemistry, with in vivo efficacy outperforming a comparable marketed ADC.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![Cell and Gene pharma manufacturing bioprocess GettyImages-1166528646]( "Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A Resins")
Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A ResinsProtein A chromatography intensification can increase productivity, but it may also affect process robustness. Explore key tradeoffs, operational challenges, and practical considerations.
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![GettyImages-899692950-cleanroom-microscopes-scientists-analyze]( "Detect Low-Abundance GLP-1 Impurities With Greater Sensitivity")
Detect Low-Abundance GLP-1 Impurities With Greater SensitivityLow-level impurities can be difficult to resolve using conventional approaches. Discover how a Charged Surface 2.3 µm superficially porous Phenyl-Hexyl column enhances reversed-phase LC-MS analysis.
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![GettyImages-1309780330-HPLC-lab-scientist-chromatography]( "Differentiate Challenging Site-Specific Isomeric Amino Acids")
Differentiate Challenging Site-Specific Isomeric Amino AcidsLearn how high-resolution ion mobility, pre-IMS fragmentation, and product ion analysis can resolve difficult peptide isomers and localize structural differences, supporting confident characterization.
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![Female researcher analyzing scientific samples-GettyImages-2231025177]( "Increase Throughput For Intact Mass Confirmation And Impurity Screening")
Increase Throughput For Intact Mass Confirmation And Impurity ScreeningAccelerate intact mass analysis of GLP-1 analogues with automated purity calculations, sub-ppm mass accuracy, and impurity detection for consistent results in under one minute per sample.
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![quality control, sterile pharmaceutical manufacturing facility-GettyImages-2277115553]( "Integrated QC As A Development Strategy: Reducing Late-Stage Analytical Risk")
Integrated QC As A Development Strategy: Reducing Late-Stage Analytical RiskLearn how early QC integration, proactive analytical risk management, and cross-functional collaboration can improve validation readiness, reduce development surprises, strengthen release testing predictability, and help protect critical clinical manufacturing timelines.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Emulate's kits provide the essential components needed to create functional, living organ models on the Zoë® Culture Module.
Outsourcing can accelerate development by reducing operational complexity while providing access to expert partners, advanced technologies, and scalable manufacturing.
S APO Greenough Stereo Microscope
Save up to 20% inspection and rework time*
Continuously improving production, keeping defect rates low, and fulfilling customer requests in order to stay competitive can be very challenging. Leica has developed the S9 stereo microscope series to help you cope with these challenges. With this generation of Greenough stereo microscopes operators will be able to reveal details faster as they spend less time having to adjust the microscope.
*compared to the standard industrial stereo microscope S6 from Leica
The most powerful and versatile rheometer for your laboratory.
Leica EZ
The Leica EZ4 educational stereomicroscope with 4.4:1 zoom for entry level university and college courses such as biology, anatomy and chemistry provides over 20 years of bright LED illumination which saves time and cost of replacement bulbs.
Dissection Perfection
Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.
STELLARIS 5 Cryo Confocal Light Microscope
The STELLARIS 5 Cryo is a confocal light microscope system that helps you to target your area of interest for cryo-electron tomography (CryoET). The STELLARIS 5 Cryo gives you the precision to target reliably, while still offering superior performance you can count on and improved productivity for your experiments.
Nanoform’s proprietary bionanoparticle technology can deliver large-molecule drug particles as small as 50 nm while retaining biological activity. This can not only enable more patient-friendly approaches to drug delivery, but also potentially higher loads of active ingredients.
FORMULATION DEVELOPMENT SOLUTIONS
- A Streamlined Approach For The APC Labeling/Conjugation Of Antibodies
- Pre-Formulation And Material Sciences
- Cell Culture Media For Viral Vector Production
- Expediting Drug Discovery From Concept To Commercialization
- High-Content Screening System
- CDO Services: Agile. Flexible. Focused On You.
- Quadrant 2™: Predictive Platform For Solubility And Bioavailability Enhancement
- Drive Your Performance Forward With The Expanded Family Of Efficient-Pro Feeds
- A Rapid Workflow For High‑Resolution Protein Analysis
- The Way Forward In Antibody Therapeutics Purification
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Jubilant HollisterStier Announces First FDA Commercial Product Approval For Sterile Fill-Finish Line 3
- Ardena To Attend CPHI Worldwide Milan 2026, Launching Charity Step Challenge "From Molecules To Miles"
- AST Names Industry Veteran Jon Lenihan As Chief Commercial Officer
- JHS And Altoura Selected For BioTools Innovator VANGUARD Level Up-XR Program
- Syntegon Launches New Pilot Scale Tablet Coater For Small Batches
- Cambrex High Point Completes FDA, PMDA And TGA PreApproval Inspections, Advancing Commercial Manufacturing Capabilities
- CleanSpace Names Pharma Industry Veteran Will Knapp Midwest Sales Director
- METTLER TOLEDO Introduces LightningBuild Program For Four-Week Delivery
- Eurofins CDMO Alphora Expands Kilolab And High Potency Development And Manufacturing Capabilities
- Ypsomed Opens Production Site In China