Formulation Development

Calculators & Predictors for LogP, LogD, pK_a, Aqueous Solubility, and more…

The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.

ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.

• Predict aqueous solubility,^* boiling point, logD,^* logP,^* pK_a,^* Sigma, and other molecular descriptors for organic compounds, from structure
• Evaluate the calculated results with sorting, plotting tools
• Assess the reliability of predicted physicochemical property values
• Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
• Train predictors with experimental data to better reflect novel chemical space
• Include custom models and in-house prediction algorithms

^*Models are trainable with experimental data

For more than 30 years Curia has been meeting the custom synthesis needs of our clients.

Get Systematic Chemical Names for Structures, and Produce Structures from Names

ACD/Name generates chemical names according to IUPAC rules, converts chemical names to structures, and easily handles challenging areas of nomenclature.

• Generate names for organic; biochemical; and some inorganic, organometallic, and polymer structures
• Convert systematic or trivial names to structures

Leica DM2000

With their sophisticated modular design and high-performance fluorescence, the Leica DM2000 microscopes are ideal for complex tasks in pathology, cytology, and many other applications. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).

STELLARIS DLS Digital Light Sheet Microscope

Light Sheet Re-Imagined

STELLARIS 5 and STELLARIS 8 Digital LightSheet (DLS) unite in one place a confocal system and a light sheet microscope – a unique combination aimed to make your research more versatile. The exclusive vertical design of DLS, enabled by Leica Microsystems’ proprietary TwinFlect mirrors, allows you to combine confocal and light sheet imaging in the same system, so you can easily adapt the microscopy method to your experimental needs.

DLS also brings flexibility to your research with the capacity to image different types of samples, such as model organisms, organoids or cleared tissue, and the ability to take advantage of the full excitation spectrum. This flexibility is possible thanks to the STELLARIS White Light Laser and the ability to perform multi-position light sheet experiments whilst using standard glass bottom plates. All of this helps you add new and better ways to explore your research questions.

Rules-Based Fragment Prediction for Mass Spectrometry

ACD/MS Fragmenter helps you predict mass spectral fragmentation in seconds. Have more confidence in your compound IDs, learn about fragmentation mechanisms, and publish your results easily.

It’s as simple as this:

• Draw your compound
• Select the ionization polarity and fragmentation options
• View its fragmentation tree

Cell DIVE Multiplex Imaging Solution

What if every scientist could map normal and diseased tissue by cell type, biomarker profile, and specific features?

Cell DIVE is a precise, open multiplexing solution that lets your research dictate the level of automation required, which antibodies to use, how to build your antibody panel, and more.

ÄKTA ready™ chromatography system 450 is a single-use liquid chromatography system.