Formulation Development

STELLARIS 8 CRS Coherent Raman Scattering Microscope 

When you need to study structures that cannot be visualized with traditional fluorescent microscopy methods, the STELLARIS 8 Coherent Raman Scattering (CRS) microscope enables you to implement label-free chemical imaging into your workflow to answer those challenging research questions.

Synthetic oligonucleotide therapeutics, such as antisense oligonucleotides (ASOs) and small interfering RNAs (si-RNAs), require thorough analysis to establish purity and quality.

The 3D Ready™ Organoid Expansion Service provides researchers with large numbers of high quality, low-variability organoids in a convenient assay-ready format.

Encoded stereo microscopes Leica M165 C​ - Total recall of your settings

Your goal: high-quality images that allow measurements and can be accurately repeated with minimal effort. The Leica coded stereo microscopes help you to pave the way to correct results.

• Coded microscopes consistently deliver calibrated and comparable images

• Reproduce images in moments with the Leica “Store and Recall” function

• Fully apochromatic corrected zoom optics deliver high quality images

• Customize the microscope system to your task with the exclusive range of accessories

STELLARIS STED Microscope

Get faster to the truth

Our STED (stimulated emission depletion) technology joins the STELLARIS platform to provide you the fastest way of imaging beyond the diffraction limit. Obtain cutting-edge nanoscopy results in no time with astounding image quality and resolution, while protecting your sample. STED super-resolution allows you to study multiple dynamic events simultaneously, so you can investigate molecular relationships and mechanisms within the cellular context.

The seamless integration of STED and STELLARIS provides easy access to STED directly from the confocal interface, making it just a few clicks away. Now you can get more insights from your sample, because every detail matters.

Calculators & Predictors for LogP, LogD, pK_a, Aqueous Solubility, and more…

The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.

ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.

• Predict aqueous solubility,^* boiling point, logD,^* logP,^* pK_a,^* Sigma, and other molecular descriptors for organic compounds, from structure
• Evaluate the calculated results with sorting, plotting tools
• Assess the reliability of predicted physicochemical property values
• Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
• Train predictors with experimental data to better reflect novel chemical space
• Include custom models and in-house prediction algorithms

^*Models are trainable with experimental data

Reproducibility, reliability and carryover performance that meets your workflow demands, injection to injection, batch after batch.

ExionLC 2.0 and ExionLC 2.0+ systems provide full integration, control and compatibility with SCIEX mass spectrometers bringing together the speed and precision you expect for a complete solution that meets every challenge your lab faces.

The Intabio ZT system couples icIEF separation and UV detection with high resolution mass spectrometry on the ZenoTOF 7600 system.