Formulation Development

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

  • Using DSC And MDSC To Study Material Interactions Of APIs And Excipients

    Thermal analysis reveals how particle size and morphology influence material interactions and stability. Learn how DSC and MDSC techniques uncover compatibility issues and guide better excipient selection.

  • Remote Measurements For Bulk Samples

    Remote Raman spectroscopy enables accurate material identification at long distances without complex focusing. Learn how pathlength, sample properties, and substrate choice impact signal quality.

  • Lentiviral Vector Upstream Process

    Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.

  • Aggregate Analysis Of Tirzepatide

    A new size exclusion method effectively analyzes Tirzepatide aggregates, demonstrating robust separation and reproducibility with minimal need for organic solvents or acidic modifiers.

  • Aggregate Analysis Of Semaglutide

    Effective size exclusion chromatography (SEC) for Semaglutide aggregate analysis is possible without high organic solvents or acidic modifiers. Learn about this robust method for improved efficacy.

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

S APO Greenough Stereo Microscope

Save up to 20% inspection and rework time*

Continuously improving production, keeping defect rates low, and fulfilling customer requests in order to stay competitive can be very challenging. Leica has developed the S9 stereo microscope series to help you cope with these challenges. With this generation of Greenough stereo microscopes operators will be able to reveal details faster as they spend less time having to adjust the microscope.

*compared to the standard industrial stereo microscope S6 from Leica

Cell DIVE Multiplex Imaging Solution

What if every scientist could map normal and diseased tissue by cell type, biomarker profile, and specific features?

Cell DIVE is a precise, open multiplexing solution that lets your research dictate the level of automation required, which antibodies to use, how to build your antibody panel, and more.

Improve precision in ADME and Toxicology applications with a low-drug-absorption profile.

The systems can be provided in sterile, toxic or sterile toxic arrangements with the great advantage of being 100 % scalable.

ÄKTA ready™ 450 system is a single-use liquid chromatography system.

Leica M60 Routine Stereo Microscopes 

Easily inspect, screen, observe or document. Handle your daily inspection or documentation, work confidently, and stay flexible in times of change. The modular stereo microscopes of the M series from Leica are the right choice for an abundant variety of tasks in life sciences and industrial applications.

The M50, M60, and M80 allow operators to see a large sample overview, work comfortably under the microscope, and capture images of important details easily.

LMD 6 Laser Microdissection Microscope

Dissection Perfection

Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.

LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.

We move the laser, not the sample. And we use gravity for collection. That is why our LMD systems provide you with perfectly cut, contamination-free, analysis-ready dissectates.

With high-performance optics and ergonomic design, the Leica DM IL LED is ideal for cell culture, micromanipulation, documentation of immunostained specimens, and routine live cell examinations.

The Leica DM IL LED features a comprehensive set of contrast methods to monitor your specimen the way you need. High-quality Phase contrast, excellent modulation contrast and brilliant fluorescence are just one fingertip away. Robust stability, plenty of space to work with tools, long working distances to accommodate large culture flasks and a stable illumination without heat make work at the microscope easy and convenient.

For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) including in-vitro-fertilization (IVF).