Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![GettyImages-1294339667-scientists-protective-gear-tablet-teamwork]( "Nitrosamine Risk Management: Your Questions Answered")
Nitrosamine Risk Management: Your Questions AnsweredNavigate nitrosamine impurities with early risk assessments, trace-level analytical testing, and careful excipient evaluation. Learn strategies to strengthen compliance and optimize testing programs.
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![GettyImages-1407655244-dry-podwer-injectable-injector]( "Advancing Reconstitutable Injectables: Aseptic Powder Filling & Dual Chamber Delivery")
Advancing Reconstitutable Injectables: Aseptic Powder Filling & Dual Chamber DeliverySpray-dried powders, gravimetric filling, and dual-chamber syringes are converging into one development pathway for reconstitutable injectables, raising the question of how formulation, filling accuracy, and device design should be evaluated together.
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![science laboratory research, healthcare innovation, development, investigation-GettyImages-1751659695]( "Choosing The Right Solid Form")
Choosing The Right Solid FormMastering polymorph screening helps prevent costly reformulation delays. Explore phase-appropriate strategies, experimental methods, and structural informatics for crystal form selection.
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![Blood diagnostics, laboratory testing, disease biomarkers, medical technology-GettyImages-2218591456]( "From Biomarker Data To Proof Of Mechanism")
From Biomarker Data To Proof Of MechanismBiomarker values support mechanism only when the decision, analytical plan, and validation are designed as one chain, with expected direction of change and baseline noise defined before sampling.
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![trialkit-api-GettyImages-2223712653]( "Difficult-To-Purify And Difficult-To-Filter Small Molecules")
Difficult-To-Purify And Difficult-To-Filter Small MoleculesPoor filterability and stubborn impurities often trace back to the same molecular features, which changes how development teams approach scale-up for larger, structurally complex small molecules.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![GettyImages-2190227480-laboratory-scientists-computer-equipment-research]( "Building Confidence In Combination Product Development")
Building Confidence In Combination Product DevelopmentEarly compatibility testing with realistic placebo models helps mitigate formulation risks, ensuring accurate dosing, predictable injection times, and long-term stability.
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![partnership or agreement in the pharmaceutical industry-GettyImages-2173667078]( "From Early Development To Commercial Launch: An End-To-End Partnership")
From Early Development To Commercial Launch: An End-To-End PartnershipBringing a critical therapy to market takes early coordination. See how strategic planning helped accelerate an oncology therapy from clinical development to patients.
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![pharmacology, chemistry, micropipette, biotechnology, Liquid Chromatography-GettyImages-1494345439]( "Selecting The Right Chromatography Strategy")
Selecting The Right Chromatography StrategyDifficult small molecule purifications rarely yield to one technique. Modeling, fraction mapping, and preparative HPLC each solve a different problem, and the right choice depends on the molecule.
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![GettyImages-1052204504-crystallization]( "Optimizing Particle Properties For Difficult Small Molecules")
Optimizing Particle Properties For Difficult Small MoleculesCrystal morphology and unexpected solid-state intermediates often decide whether a difficult small molecule filters, dries, and scales. Thermodynamic stability may not be the right target.
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![science laboratory research, healthcare innovation, development, investigation-GettyImages-1751659695]( "Turning A \"Brick Dust\" Compound Into A Clinically Viable Oral Formulation")
Turning A "Brick Dust" Compound Into A Clinically Viable Oral FormulationAdvanced wet milling and particle stabilization improve solubility, enhance bioavailability, and support scalable manufacturing for complex oral drug development programs.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Custom microscopy workstations to meet your advanced imaging needs.
Enabling you to design vaccines without reliance on animal sources with our fermentation-produced squalene.
SoftMax® Pro Software - The most published microplate reader control and data analysis software
Preconfigured protocols and custom assay workflows simplify microplate data acquisition and analysis
SoftMax® Pro Software for Windows 10 is designed to provide the simplicity, flexibility and power required for advanced data analysis. It provides ready-to-run protocols, analysis algorithms, and 21 different curve fit options. Every step is optimized for data acquired from a Molecular Devices microplate reader or data imported from another source to simplify analysis and reporting. Compliance tools are available for regulated laboratories providing end-to-end chain of custody.
Unexpected downtime can drastically impact your organization’s ability to service customers and hinder innovation. With Waters FlexCHOICE: mySystem Coverage*, you can safeguard against lost productivity and unexpected downtime and spend more time on what matters most – your customers and your research.
Curia was the first CRO to provide contract medicinal chemistry services to the pharmaceutical industry.
Your Method Development Toolbox
ACD/Method Selection Suite is your software assistant for LC and GC method development. When you want to develop methods using Quality by Design (QbD) principles, and make every experiment count, reach for Method Selection Suite to:
- Choose your starting conditions and columns
- Simulate separations under new conditions
- Optimize your chromatography with 1D, 2D, or 3D models
- Predict the retention times of new compounds
- Database successful methods for future use
The Percepta Platform is a portfolio of software applications and a technology ecosystem for predicting and managing physicochemical, ADME/Tox, and other molecular property data.
With Percepta applications you can predict molecular properties from structure, and train models with experimental data. You can even include custom models created in-house to centrally manage in silico calculations and training sets for distribution so that everyone calculating property data is using up-to-date information.
Accelerate your gene therapy manufacturing with the Xcellerex™ X-platform – a next-generation single-use bioreactor system designed for viral vector workflows.
FORMULATION DEVELOPMENT SOLUTIONS
- Upadacitinib API Development For Regulatory Purposes
- A Streamlined Approach For The APC Labeling/Conjugation Of Antibodies
- ACQUITY Premier Analytical Solution
- Accelerate Molecules Through Development With Translational Pharmaceutics®
- Custom Organ-Chip Models For A Wide Variety Of Applications
- Human ADME Studies: Human Metabolism Data For Regulatory Submission
- API Stability Combined With Rapid Disintegration
- LABIO 4.0 Marino Golinelli R&D Pharmaceutical Center
- Is NSA Sabotaging Your Lab's Productivity
- Getting Solid Form Right The First Time