Formulation Development

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

  • Using DSC And MDSC To Study Material Interactions Of APIs And Excipients

    Thermal analysis reveals how particle size and morphology influence material interactions and stability. Learn how DSC and MDSC techniques uncover compatibility issues and guide better excipient selection.

  • Remote Measurements For Bulk Samples

    Remote Raman spectroscopy enables accurate material identification at long distances without complex focusing. Learn how pathlength, sample properties, and substrate choice impact signal quality.

  • Lentiviral Vector Upstream Process

    Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.

  • Aggregate Analysis Of Tirzepatide

    A new size exclusion method effectively analyzes Tirzepatide aggregates, demonstrating robust separation and reproducibility with minimal need for organic solvents or acidic modifiers.

  • Aggregate Analysis Of Semaglutide

    Effective size exclusion chromatography (SEC) for Semaglutide aggregate analysis is possible without high organic solvents or acidic modifiers. Learn about this robust method for improved efficacy.

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

Accelerate your gene therapy manufacturing with the Xcellerex™ X-platform – a next-generation single-use bioreactor system designed for viral vector workflows.

We have developed an innovative portfolio of affinity chromatography resins to help you solve challenges in the downstream process of next-generation antibody therapeutics. These resins are specifically designed for the purification of engineered monoclonal antibody (mAbs) modalities.

Decode 3D biology in real time*

The THUNDER Imager Model Organism allows fast and easy 3D exploration of whole organisms for developmental or molecular biology research. Thanks to THUNDER Live, your images reveal the finest structural details already in the live image. No hassle with out-of-focus blur while maintaining the capabilities and ease-of-use typical for Leica stereo microscopes.

A THUNDER Imager Model Organism is the optimal instrument for studying, e.g., Drosophila, C. elegans, zebrafish, plants, and mice. One device for screening, positioning, and imaging your specimen. Simplify your workflow and study model organisms from a large overview to the highest detail.

Unique confocal imaging solution capable of imaging more than a million wells a week

The ImageXpress® Micro Confocal system is a high-content solution that can switch between widefield and confocal imaging of fixed and live cells.

A60 F Stereo Microscope 

Optimize your productivity and production quality

The intuitive A60 F and A60 S stereo microscopes fulfill what you need – high sample throughput, optimum visibility of product details and components, and easy processing of subassemblies.

  • See 80% more of your sample with a 46 mm object field

  • Comfortable access your sample due to the 122 mm working distance

  • Easy handling, less refocusing and time saving with up to 13.6 mm depth of field and Leica FusionOptics technology

  • Enables large surface overview and detailed observation with a magnification range from 5x to 30x

S APO Greenough Stereo Microscope

Save up to 20% inspection and rework time*

Continuously improving production, keeping defect rates low, and fulfilling customer requests in order to stay competitive can be very challenging. Leica has developed the S9 stereo microscope series to help you cope with these challenges. With this generation of Greenough stereo microscopes operators will be able to reveal details faster as they spend less time having to adjust the microscope.

*compared to the standard industrial stereo microscope S6 from Leica

The THUNDER Imager Tissue allows real-time fluorescence imaging of 3D tissue sections typically used in neuroscience and histology research. Acquire rich, detailed images of thick tissues free of haze from out-of-focus blur.

Even fine structures deep in tissues can be resolved thanks to Computational Clearing, an innovative Leica technology. Image detailed morphological structures like axons and dendrites of neurons in a brain slice. The high image quality, even with thick tissue sections, is combined with the well-known speed, fluorescence efficiency, and ease of use of widefield microscopes.

Leica DM300

For slightly more advanced students in biology or 2-4 year college life science classrooms, the Leica DM300 compound microscope is compact, maintenance-free and easy to use to provide trouble free operation each day.

Equipped with a mechanical stage to accommodate two specimen slides and labelled Abbe condenser, the DM300 can be configured with rotatable monocular or binocular tubes for shared viewing and easy storage. Trinocular tube is also possible to go digital.

With 165 years of microscope design and manufacturing experience, the Leica DM300 student microscope provides students with the capabilities they need to study the finest details in all the Life Sciences.