Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![Blood diagnostics, laboratory testing, disease biomarkers, medical technology-GettyImages-2218591456]( "From Biomarker Data To Proof Of Mechanism")
From Biomarker Data To Proof Of MechanismBiomarker values support mechanism only when the decision, analytical plan, and validation are designed as one chain, with expected direction of change and baseline noise defined before sampling.
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![GettyImages-2184563761 molecules]( "Expert Q&A: Navigating Complexity In Modern Small Molecule Development")
Expert Q&A: Navigating Complexity In Modern Small Molecule DevelopmentSmall molecules are growing larger, more potent, and more structurally complex while timelines compress. That combination reshapes scale-up, outsourcing relationships, and the criteria for choosing a manufacturing partner.
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![capsule-development-GettyImages-2215837457]( "A Connected Approach To OSD Development")
A Connected Approach To OSD DevelopmentSee how an integrated OSD development strategy can identify risks early, strengthen process understanding and prepare products for scale-up, tech transfer and commercialization.
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![iStock-459537393-pill-softgel-capsule]( "Is Your API Right For A Soft Gel Capsule?")
Is Your API Right For A Soft Gel Capsule?Soft gel delivery systems can enhance bioavailability, enable controlled release, support combination dosing, and handle potent compounds while improving stability and patient adherence.
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![GettyImages-1032667996-Softgels]( "How A CDMO Overcomes Soft Gel Formulation Challenges")
How A CDMO Overcomes Soft Gel Formulation ChallengesSoftgel development demands careful control of shell properties, liquid fills, and stability. Overcoming formulation challenges improves drug delivery, bioavailability, and shelf life.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![partnership or agreement in the pharmaceutical industry-GettyImages-2173667078]( "From Early Development To Commercial Launch: An End-To-End Partnership")
From Early Development To Commercial Launch: An End-To-End PartnershipBringing a critical therapy to market takes early coordination. See how strategic planning helped accelerate an oncology therapy from clinical development to patients.
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![science laboratory research, healthcare innovation, development, investigation-GettyImages-1751659695]( "Turning A \"Brick Dust\" Compound Into A Clinically Viable Oral Formulation")
Turning A "Brick Dust" Compound Into A Clinically Viable Oral FormulationAdvanced wet milling and particle stabilization improve solubility, enhance bioavailability, and support scalable manufacturing for complex oral drug development programs.
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![Drug R-D_GettyImages-1483266787]( "Creating A New Dosage Form From An Approved Drug For A New Rare Disease")
Creating A New Dosage Form From An Approved Drug For A New Rare DiseaseAdvancing approved drugs into new indications requires smart formulation, strong quality controls, and regulatory expertise to overcome challenges and accelerate patient access.
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![Test tubes, dropper, scientist in lab-GettyImages-2157720330]( "Improved Oligonucleotide LC–MS Performance")
Improved Oligonucleotide LC–MS PerformanceMetal surfaces and PFAS-based ion-pair reagents limit oligonucleotide LC-MS. Inert hardware and ion-pair-free separation modes change recovery, resolution, and spectral clarity in ways worth examining.
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![samples under microscopes, analyze data-GettyImages-2191794159]( "Integrated LC/UV And LC/MS Workflows For Impurity And Degradation")
Integrated LC/UV And LC/MS Workflows For Impurity And DegradationFatty acid-modified GLP-1 peptides carry hydrophobicity and impurity profiles that strain separation. Pairing LC/UV with mass spectrometry exposes degradation and supplier-to-supplier differences.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Routine cell culture? Check!
For researchers who need consistent experimental outcomes, Mateo TL enables all lab members to check and document cell growth status conveniently and comfortably.
Measure confluency consistently, thereby increasing the confidence in the success of their downstream experiments.
MabSelect™ VL resin — protein L resin for affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
Our comprehensive pharmaceutical development service offering includes new drug development, early stage formulation and analytical development for both highly potent and non-potent drug products.
Unique confocal imaging solution capable of imaging more than a million wells a week
The ImageXpress® Micro Confocal system is a high-content solution that can switch between widefield and confocal imaging of fixed and live cells.
Upperton offers formulation development services to accelerate First-in-Human studies and advance projects toward clinical trials.
In silico modeling technologies are transforming drug development and manufacturing by enhancing efficiency, accuracy, to allow innovations.
The LevMixer™ 10 L single-use mixing system is a low volume mixer designed for both upstream and downstream applications.
LMD 6 Laser Microdissection Microscope
Dissection Perfection
Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.
LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.
We move the laser, not the sample. And we use gravity for collection. That is why our LMD systems provide you with perfectly cut, contamination-free, analysis-ready dissectates.
FORMULATION DEVELOPMENT SOLUTIONS
- Lyophilization And Sterile Manufacturing
- Guarantee A Successful Expansion With An Organoid Expansion Service
- A High-Purity Excipient Suitable For High-Risk Vaccine Applications
- Microcalorimetry: ITC & DSC
- Chip-R1™ Basic Research Kit
- Colon Intestine Bio-Kit
- LC And LC-MS Chemistry Consumables For Bioseparations
- Is NSA Sabotaging Your Lab's Productivity
- Your End-To-End CDMO Partner
- RNA 9000 Purity & Integrity Kit
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Lonza Signs Agreement To Acquire US CDMO Network From Merck KGaA, Darmstadt, Germany, And Significantly Expands Its US Presence
- Bracco To Build New Injectable Drug Manufacturing Facility In North Carolina
- Lonza Further Expands Bioconjugation Manufacturing To Support Growing ADC Demand
- ROSS Portable High Shear Mixing System
- Ardena Launches Online Biomarker Catalogue: 228 Markers, One Quote Request
- Meissner Hosts Ribbon Cutting Ceremony For X-Ray Irradiation Services And Breaks Ground On Phase 2 Of Its Athens, Georgia, U.S.A. Campus
- Global Pharma Manufacturing Community Meets In Berlin For PHARMAP 2027
- LGM Pharma Acquires Sannova Analytical, Expanding cGMP Analytical And GLP Bioanalytical Services
- MVIC And Upperton Pharma Solutions Announce Strategic Collaboration
- All-In-One Solution For Continuous Microbial Monitoring Without Production Interruptions