Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![cdmo-solid-dose-GettyImages-1432665138]( "How To Achieve Late-Phase Success In Complex OSD Development")
How To Achieve Late-Phase Success In Complex OSD DevelopmentLate-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.
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![GettyImages-1194851415-OSD-oral-solid-tablet-pill-capsule]( "Reducing Uncertainty In Early Oral Drug Development")
Reducing Uncertainty In Early Oral Drug DevelopmentFive recurring decision points in early oral solid dose development carry outsized downstream consequences. AI/ML-driven predictive modeling is reframing how teams manage those decisions under API and timeline constraints.
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![GettyImages-2270210340-lipid-nanoparticle-delivery-system]( "Lipid Formulation Development: Why Softgels Are The Technology Of Choice")
Lipid Formulation Development: Why Softgels Are The Technology Of ChoiceLow bioavailability affects roughly 80% of APIs, yet many drug developers default to standard OSD forms. This paper examines why softgels deserve earlier consideration in formulation strategy.
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![GettyImages-950086574-oral-solid-OSD-pill-tablet-capsule-development]( "5 Hidden Risks In Early-Phase OSD Formulation Development")
5 Hidden Risks In Early-Phase OSD Formulation DevelopmentEarly formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.
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![GettyImages-1370967510 hot cold]( "Overview Of Hot Melt Extrusion And Its Pharmaceutical Applications")
Overview Of Hot Melt Extrusion And Its Pharmaceutical ApplicationsMore than 40% of NCEs face aqueous solubility challenges. Here, we examine how hot melt extrusion addresses solubility, modified release, abuse deterrence, and scale-up across pharmaceutical development.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![GettyImages-528971880 chromatography]( "Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A Resins")
Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A ResinsProtein A chromatography intensification can increase productivity, but it may also affect process robustness. Explore key tradeoffs, operational challenges, and practical considerations.
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![GettyImages-899692950-cleanroom-microscopes-scientists-analyze]( "Detect Low-Abundance GLP-1 Impurities With Greater Sensitivity")
Detect Low-Abundance GLP-1 Impurities With Greater SensitivityLow-level impurities can be difficult to resolve using conventional approaches. Discover how a Charged Surface 2.3 µm superficially porous Phenyl-Hexyl column enhances reversed-phase LC-MS analysis.
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![GettyImages-1309780330-HPLC-lab-scientist-chromatography]( "Differentiate Challenging Site-Specific Isomeric Amino Acids")
Differentiate Challenging Site-Specific Isomeric Amino AcidsLearn how high-resolution ion mobility, pre-IMS fragmentation, and product ion analysis can resolve difficult peptide isomers and localize structural differences, supporting confident characterization.
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![Female researcher analyzing scientific samples-GettyImages-2231025177]( "Increase Throughput For Intact Mass Confirmation And Impurity Screening")
Increase Throughput For Intact Mass Confirmation And Impurity ScreeningAccelerate intact mass analysis of GLP-1 analogues with automated purity calculations, sub-ppm mass accuracy, and impurity detection for consistent results in under one minute per sample.
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![quality control, sterile pharmaceutical manufacturing facility-GettyImages-2277115553]( "Integrated QC As A Development Strategy: Reducing Late-Stage Analytical Risk")
Integrated QC As A Development Strategy: Reducing Late-Stage Analytical RiskLearn how early QC integration, proactive analytical risk management, and cross-functional collaboration can improve validation readiness, reduce development surprises, strengthen release testing predictability, and help protect critical clinical manufacturing timelines.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Leica DM500 Binocular
Supports a Student Friendly Classroom Environment For Life Science Courses
The Leica DM500 microscope with “plug and play” capability is the ideal tool to make teaching entry-level college and university Life Science courses easy and fun for the instructor and the student.
Student-friendly features such as the pre-focused, pre-centered condenser and the EZTube™ preset diopter, which prevent incorrect adjustments, provide more time for hands-on teaching.
EZStore™ design with integrated handle and cord wrap allows easy carrying, easy lifting and protection against microscope component damage.
The LevMixer™ 10 L single-use mixing system is a low volume mixer designed for both upstream and downstream applications.
Digital microscopy with automated brightfield, fluorescence, and Digital Confocal imaging
The ImageXpress® Pico Automated Cell Imaging System is more than a digital microscope, combining high-resolution imaging with powerful analysis. Whether running fluorescence imaging or brightfield assays, the automated imager features a comprehensive portfolio of preconfigured protocols for cell-based assays to shorten the learning curve, so you can start running experiments quickly.
Evaluating small and large molecule therapeutics within cellular environments is essential to understanding their efficacy, potency, and safety within a complex biological system.
12 MP Microscope Camera Flexacam C3
Save time when capturing, documenting, and sharing images with the Flexacam C3 microscope camera. It transforms your microscope into a stand-alone digital imaging station without the need for a PC.
Make reliable and accurate decisions for your application tasks with powerful color accuracy. True-to-life colors and fine details are a given thanks to the 12 MP CMOS sensor, large dynamic range, and fast signal processing.
Collaborate in real time and review images efficiently as a team by taking advantage of the fast display of live images.
THUNDER Imager Live Cell & 3D Assay
Decode 3D biology in real time*
With THUNDER Imagers you begin every experiment with confidence. They are your solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids.
Configurable, high-throughput widefield imaging solution for an incredible range of assays
A scalable, high-throughput, high-content screening solution with 7-channel high-intensity laser light source and machine learning capabilities.
FORMULATION DEVELOPMENT SOLUTIONS
- Automated Cell Imaging System
- Guarantee A Successful Expansion With An Organoid Expansion Service
- High Potency API Development And Manufacturing
- Inhaled Product Development
- Robust Methods With Fewer Injections
- High-Throughput Cellular Screening System
- HyClone™ Peak Expression Medium
- Speed, Scale, And Supply With Innovative Cell Culture Solutions
- A Rapid Workflow For High‑Resolution Protein Analysis
- Human Proximal Tubule Kidney Bio-Kit
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- AST Names Industry Veteran Jon Lenihan As Chief Commercial Officer
- JHS And Altoura Selected For BioTools Innovator VANGUARD Level Up-XR Program
- Syntegon Launches New Pilot Scale Tablet Coater For Small Batches
- Cambrex High Point Completes FDA, PMDA And TGA PreApproval Inspections, Advancing Commercial Manufacturing Capabilities
- CleanSpace Names Pharma Industry Veteran Will Knapp Midwest Sales Director
- METTLER TOLEDO Introduces LightningBuild Program For Four-Week Delivery
- Eurofins CDMO Alphora Expands Kilolab And High Potency Development And Manufacturing Capabilities
- Ypsomed Opens Production Site In China
- Ypsomed Launches YpsoLoop As The First Autoinjector Platform Designed For Circularity
- Ypsomed Expands Offering For Clinical Studies