Formulation Development

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

  • Using DSC And MDSC To Study Material Interactions Of APIs And Excipients

    Thermal analysis reveals how particle size and morphology influence material interactions and stability. Learn how DSC and MDSC techniques uncover compatibility issues and guide better excipient selection.

  • Remote Measurements For Bulk Samples

    Remote Raman spectroscopy enables accurate material identification at long distances without complex focusing. Learn how pathlength, sample properties, and substrate choice impact signal quality.

  • Lentiviral Vector Upstream Process

    Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.

  • Aggregate Analysis Of Tirzepatide

    A new size exclusion method effectively analyzes Tirzepatide aggregates, demonstrating robust separation and reproducibility with minimal need for organic solvents or acidic modifiers.

  • Aggregate Analysis Of Semaglutide

    Effective size exclusion chromatography (SEC) for Semaglutide aggregate analysis is possible without high organic solvents or acidic modifiers. Learn about this robust method for improved efficacy.

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

Encoded stereo microscopes Leica M165 C​ - Total recall of your settings

Your goal: high-quality images that allow measurements and can be accurately repeated with minimal effort. The Leica coded stereo microscopes help you to pave the way to correct results.

  • Coded microscopes consistently deliver calibrated and comparable images

  • Reproduce images in moments with the Leica “Store and Recall” function

  • Fully apochromatic corrected zoom optics deliver high quality images

  • Customize the microscope system to your task with the exclusive range of accessories

STELLARIS STED Microscope

Get faster to the truth

Our STED (stimulated emission depletion) technology joins the STELLARIS platform to provide you the fastest way of imaging beyond the diffraction limit. Obtain cutting-edge nanoscopy results in no time with astounding image quality and resolution, while protecting your sample. STED super-resolution allows you to study multiple dynamic events simultaneously, so you can investigate molecular relationships and mechanisms within the cellular context.

The seamless integration of STED and STELLARIS provides easy access to STED directly from the confocal interface, making it just a few clicks away. Now you can get more insights from your sample, because every detail matters.

Leica EZ

The Leica EZ4 educational stereomicroscope with 4.4:1 zoom for entry level university and college courses such as biology, anatomy and chemistry provides over 20 years of bright LED illumination which saves time and cost of replacement bulbs.

The THUNDER Imager Tissue allows real-time fluorescence imaging of 3D tissue sections typically used in neuroscience and histology research. Acquire rich, detailed images of thick tissues free of haze from out-of-focus blur.

Even fine structures deep in tissues can be resolved thanks to Computational Clearing, an innovative Leica technology. Image detailed morphological structures like axons and dendrites of neurons in a brain slice. The high image quality, even with thick tissue sections, is combined with the well-known speed, fluorescence efficiency, and ease of use of widefield microscopes.

Cell DIVE Multiplex Imaging Solution

What if every scientist could map normal and diseased tissue by cell type, biomarker profile, and specific features?

Cell DIVE is a precise, open multiplexing solution that lets your research dictate the level of automation required, which antibodies to use, how to build your antibody panel, and more.

We have developed an innovative portfolio of affinity chromatography resins to help you solve challenges in the downstream process of next-generation antibody therapeutics. These resins are specifically designed for the purification of engineered monoclonal antibody (mAbs) modalities.

Find the missing links

The modular DMi8 inverted microscope is the heart of the DMi8 S platform solution. For routine to live cell research, the DMi8 S platform is a complete solution. Whether you need to precisely follow the development of a single cell in a dish, screen through multiple assays, obtain single molecule resolution, or tease out behaviors of complex processes, a DMi8 S system will enable you to see more, see faster, and find the hidden.

  • See more – Increase your viewing area up to 10,000x
  • See faster – Experiments up to 5x faster
  • See the hidden – Activate, ablate, and bleach within one experiment

Quality control is a critical component for ensuring safety, efficacy, and consistency in the development and production of biologics. This comprehensive list of strategies, techniques, workflows, and best-in-class products for developing biopharmaceuticals can help you navigate the complexities of biologics and simplify the manufacturing process. Improve your quality control procedures and optimize your biologics production process with tools and expertise relied upon by researchers worldwide.