Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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Early Automation Integration Reshapes How Drugs Move
Introducing automation during R&D rather than in Phase 3 changes how processes scale. Unified data and standards-based control logic carry across bench, pilot, and commercial stages with less rework.
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Why Controlled Release Is Essential For Patient-centric Drug Development
Controlled release design can ease daily dosing burden by moderating swings in drug exposure, though the right approach depends on API properties and what manufacturing can deliver at scale.
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Everyday Medicines, Complex Manufacturing: 5 Reasons They Aren't Simple To Make
Tablets and liquid medicines look simple to the patient, but their reliability depends on formulation choices made early and on technical expertise that continues well after commercial production begins.
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Why Reagent Quality Defines Research Success
Water grade, buffer preparation, and packaging each shape whether sensitive assays hold up. Reagent selection hinges on matching purity to application sensitivity, regulatory standards, and tolerance for contamination risk.
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Peptide Building Blocks: Navigating Quality, Supply, And Scale
Non-canonical amino acids can boost peptide half-life and potency, but create challenges in impurity control, GMP classification, and sourcing. Early supplier choices are critical for commercialization.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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Long-Acting GnRH Antagonist For Advanced Prostate Cancer
Achieve rapid testosterone suppression for 6+ months with a novel low-volume subcutaneous depot formulation, eliminating the initial surge and offering a new approach for advanced prostate cancer treatment.
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Why Early Device Decisions Matter: How Immunovant Accelerated Its Program
Deferring autoinjector selection can seem to preserve flexibility, yet it often moves constraints downstream. Integrating the device during Phase IIb changed one program's timeline and removed bridging work.
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Using Human-Centered Engineering To Improve HPLC Solvent Handling
Real-world HPLC workflows show how closed-system solvent handling can address contamination, downtime, and waste across laboratory settings.
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Reducing Cycle Time By 88% Through Strategic Solvent Replacement In Pharmaceutical Development
Replacing methylene chloride in a slow, labor-intensive API step led to a single-solvent, one-pot process with a shorter reaction time and improved yield and purity.
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Improving Stability Through Science-Led OSD Reformulation
A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.
FORMULATION DEVELOPMENT SOLUTIONS
- Neurodegeneration Research
- Speed, Scale, And Supply With Innovative Cell Culture Solutions
- Capacity To Secure Your Success
- Application Handbook, Chromatography Solutions For API Manufacturers
- Custom Organ-Chips For 3D Gel Matrices And Direct Compound Dosing
- Complete Organ-Chip Solutions To Fast-Track Your Drug Discovery
- Simplify Your Linker-Payload Synthesis
- High Potency API Development And Manufacturing
- Accelerate Molecules Through Development With Translational Pharmaceutics®
- Human Proximal Tubule Kidney Bio-Kit
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Hapman To Unveil New Conveying Solution At PACK EXPO 2026
- Pharmaceutical Online Covers Honorable Mention FOYA Award Winner, Chugai Pharmaceutical Co., Ltd.
- Emerson Expands Life Sciences Scheduling Software To Optimize Quality Control Lab Testing
- GSK Announces Drug Manufacturing Expansion In Pennsylvania
- Contec Launches Sterile ReadySAT™ With PeridoxRTU® Sporicidal Wipes For Cleanrooms
- Upperton Unveils New Brand Identity Reflecting Evolution Into Specialist CDMO
- Hovione To Commission World's First ConsiGma® CDC Flex, Bringing Next-Generation Continuous Tableting To The U.S.
- Agilent Expands Oligonucleotide Manufacturing Capabilities With New Boulder Lab
- Flamma Acquires API Manufacturing Site In Padova, Italy
- Bayer Expanding U.S. Pharmaceutical Manufacturing Footprint With New Ohio Manufacturing Facility