Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![GettyImages-2238837244-compliance-meeting-regulation-regulatory]( "Why CMC Continuity Is The Missing Link Between Development And Manufacturing")
Why CMC Continuity Is The Missing Link Between Development And ManufacturingDiscover why CMC continuity is the missing link between development and manufacturing, and how preserving connected product and process knowledge helps reduce handoff risk, accelerate tech transfer, and strengthen manufacturing readiness.
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![paediatric-oral-dose-GettyImages-2251563567]( "Analytical Method Development For Paediatric Oral Dose Products")
Analytical Method Development For Paediatric Oral Dose ProductsThis article explores the key formulation and analytical challenges that pharmaceutical companies face when creating safe, effective, and age-appropriate treatments for paediatric populations.
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![Solubility And Improved Patient Outcomes-GettyImages-2277363545]( "Solubility And Improved Patient Outcomes")
Solubility And Improved Patient OutcomesPoor solubility poses major development challenges. Innovative formulation technologies and careful excipient selection can improve bioavailability and product performance.
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![GettyImages-1417391937-pharmaceutical-spray-drying-with-scientists]( "Overcoming The Obstacles Of Spray-Dried Dispersion Scale-Up")
Overcoming The Obstacles Of Spray-Dried Dispersion Scale-UpSDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.
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![iStock-1248627316-chemistry-beaker-lab-science-experiment]( "Chemoenzymatic N-glycan Conjugation Of Native mAbs Provides Homogeneous, Efficacious ADCs")
Chemoenzymatic N-glycan Conjugation Of Native mAbs Provides Homogeneous, Efficacious ADCsA chemoenzymatic two-stage protocol enables DAR2 ADCs from native, non-engineered mAbs via glycan remodeling at Asn-297 and copper-free click chemistry, with in vivo efficacy outperforming a comparable marketed ADC.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![Cell and Gene pharma manufacturing bioprocess GettyImages-1166528646]( "Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A Resins")
Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A ResinsProtein A chromatography intensification can increase productivity, but it may also affect process robustness. Explore key tradeoffs, operational challenges, and practical considerations.
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![GettyImages-899692950-cleanroom-microscopes-scientists-analyze]( "Detect Low-Abundance GLP-1 Impurities With Greater Sensitivity")
Detect Low-Abundance GLP-1 Impurities With Greater SensitivityLow-level impurities can be difficult to resolve using conventional approaches. Discover how a Charged Surface 2.3 µm superficially porous Phenyl-Hexyl column enhances reversed-phase LC-MS analysis.
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![GettyImages-1309780330-HPLC-lab-scientist-chromatography]( "Differentiate Challenging Site-Specific Isomeric Amino Acids")
Differentiate Challenging Site-Specific Isomeric Amino AcidsLearn how high-resolution ion mobility, pre-IMS fragmentation, and product ion analysis can resolve difficult peptide isomers and localize structural differences, supporting confident characterization.
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![Female researcher analyzing scientific samples-GettyImages-2231025177]( "Increase Throughput For Intact Mass Confirmation And Impurity Screening")
Increase Throughput For Intact Mass Confirmation And Impurity ScreeningAccelerate intact mass analysis of GLP-1 analogues with automated purity calculations, sub-ppm mass accuracy, and impurity detection for consistent results in under one minute per sample.
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![quality control, sterile pharmaceutical manufacturing facility-GettyImages-2277115553]( "Integrated QC As A Development Strategy: Reducing Late-Stage Analytical Risk")
Integrated QC As A Development Strategy: Reducing Late-Stage Analytical RiskLearn how early QC integration, proactive analytical risk management, and cross-functional collaboration can improve validation readiness, reduce development surprises, strengthen release testing predictability, and help protect critical clinical manufacturing timelines.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
GO BEYOND with the SCIEX 7500 system, high performance triple quadrupole LC-MS/MS mass spectrometer
Enter a new era of sensitivity and LC-MS/MS innovation with the SCIEX 7500 system. GO BEYOND current limits of sensitivity, productivity targets, ruggedness and robustness challenges. Pioneer new discoveries with this innovation.
The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling the characterization of behaviors during storage, dispensing, processing, and end-use.
Custom microscopy workstations to meet your advanced imaging needs.
We deliver custom assay development, screening, potency, and selectivity testing services for the pharmaceutical, biopharmaceutical, and agrochemical industries.
Encoded stereo microscopes Leica M165 C - Total recall of your settings
Your goal: high-quality images that allow measurements and can be accurately repeated with minimal effort. The Leica coded stereo microscopes help you to pave the way to correct results.
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Coded microscopes consistently deliver calibrated and comparable images
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Reproduce images in moments with the Leica “Store and Recall” function
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Fully apochromatic corrected zoom optics deliver high quality images
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Customize the microscope system to your task with the exclusive range of accessories
ÄKTA ready™ chromatography system 450 is a single-use liquid chromatography system.
Are you using obsolete or aging instruments simply because they continue to work? Running your laboratory with outdated technology brings about challenges beyond just headaches. Older technology may limit your performance, increase your costs, and open your lab up to risk. It may be time to investigate the real cost of using obsolete technology.
With the Waters FlexUP Technology Renewal Program, always work with the latest technology for optimum productivity and security.
The Ultimate NMR Software for Data Interpretation, Structure Characterization & Knowledge Management
ACD/NMR Workbook Suite is a comprehensive NMR software application. It features a full suite of advanced processing, analysis, and databasing functionalities for 1D and 2D NMR data from all major vendor formats.
Use NMR Workbook Suite to:
- Process and analyze NMR data easily with synchronized peak picking and assignment across datasets
- Reliably verify chemical structures
- Quantify and analyze mixtures
- Create comprehensive reports and publication-ready data
- Share, manage, and store live NMR spectra linked with structures
FORMULATION DEVELOPMENT SOLUTIONS
- Get Drug Formulation Right From The Start
- Drug-Drug Interaction (DDI) Studies
- The In Vitro Model Redefining Drug Discovery And Development
- Process Liquid Preparation Services
- CHO Residual DNA Quantitation
- Molecule To Cure. Fast.
- Eliminate Doubt With Chemistry Technical Services
- MaxPeak Premier For Glycan Analysis
- MaxPeak Premier Columns For Intact And Subunit Protein Analysis
- The Power Of One: mRNA Services
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Jubilant HollisterStier Announces First FDA Commercial Product Approval For Sterile Fill-Finish Line 3
- Ardena To Attend CPHI Worldwide Milan 2026, Launching Charity Step Challenge "From Molecules To Miles"
- AST Names Industry Veteran Jon Lenihan As Chief Commercial Officer
- JHS And Altoura Selected For BioTools Innovator VANGUARD Level Up-XR Program
- Syntegon Launches New Pilot Scale Tablet Coater For Small Batches
- Cambrex High Point Completes FDA, PMDA And TGA PreApproval Inspections, Advancing Commercial Manufacturing Capabilities
- CleanSpace Names Pharma Industry Veteran Will Knapp Midwest Sales Director
- METTLER TOLEDO Introduces LightningBuild Program For Four-Week Delivery
- Eurofins CDMO Alphora Expands Kilolab And High Potency Development And Manufacturing Capabilities
- Ypsomed Opens Production Site In China