Drug Formulation, Formulation Development

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Why Early Evaluation Of Process Parameters Matters In OSD Scale-Up

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Printing A New Path To The Brain: 3D Buccal Nanofilms For CNS Lymphoma

Engineering Better ADCs, Part 2: Characterization, CMC, And More

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Engineering Better ADCs, Part 1: MoA, Conjugation Chemistry, And More

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

A Guide To Bioavailability Enhancement
Many new drug candidates face oral bioavailability challenges. Particle engineering, lipid systems, and inclusion complexes can boost absorption, though patient variability remains a hurdle.
A Strategic Guide For Challenging Early-Phase Molecules
Early formulation decisions for high-viscosity, unstable, and potent molecules impact scale-up, regulatory flexibility, and lifecycle value. Getting them right early helps avoid costly rework.
Advancing The Development Of Syringe-Device Combinations
Defining the design for syringe-autoinjector pairings early, through shared compatibility testing, can reduce integration risk for high-viscosity biologics intended for self-administration at home.
Nasal Delivery Of Psychedelics: Next Generation Delivery Options
Psychedelic development has moved past regulatory hurdles to a question of formulation and delivery. For fast-acting molecules, dosing control and onset speed are pushing developers toward one route.
Early Automation Integration Reshapes How Drugs Move
Introducing automation during R&D rather than in Phase 3 changes how processes scale. Unified data and standards-based control logic carry across bench, pilot, and commercial stages with less rework.

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

Long-Acting GnRH Antagonist For Advanced Prostate Cancer
Achieve rapid testosterone suppression for 6+ months with a novel low-volume subcutaneous depot formulation, eliminating the initial surge and offering a new approach for advanced prostate cancer treatment.
Why Early Device Decisions Matter: How Immunovant Accelerated Its Program
Deferring autoinjector selection can seem to preserve flexibility, yet it often moves constraints downstream. Integrating the device during Phase IIb changed one program's timeline and removed bridging work.
Using Human-Centered Engineering To Improve HPLC Solvent Handling
Real-world HPLC workflows show how closed-system solvent handling can address contamination, downtime, and waste across laboratory settings.
Reducing Cycle Time By 88% Through Strategic Solvent Replacement In Pharmaceutical Development
Replacing methylene chloride in a slow, labor-intensive API step led to a single-solvent, one-pot process with a shorter reaction time and improved yield and purity.
Improving Stability Through Science-Led OSD Reformulation
A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

Drug Metabolism And Pharmacokinetics (DMPK)

Curia’s DMPK scientists deliver expert solutions for your drug discovery programs. Providing bioanalytical methods development, in vitro ADMET testing and in vivo PK and PD services that span all stages of drug discovery up to candidate selection.

Small-Scale GMP Manufacturing With ÄKTA ready™ Chromatography System 450

ÄKTA ready™ chromatography system 450 is a single-use liquid chromatography system.

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Patient-Derived Assay-Ready Organoids

Gain human-relevant insights with patient-derived assay-ready organoids.

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Sophisticated Patch-Clamp Electrophysiology Data Acquisition And Analysis Software

Preconfigured protocols and custom assay workflows simplify microplate data acquisition and analysis

SoftMax® Pro Software for Windows 10 is designed to provide the simplicity, flexibility and power required for advanced data analysis. It provides ready-to-run protocols, analysis algorithms, and 21 different curve fit options.

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In-Silico Modeling Services

In silico modeling technologies are transforming drug development and manufacturing by enhancing efficiency, accuracy, to allow innovations.

CD34+ HSC LNP Kits

Research Use Only (RUO) lipid nanoparticle (LNP) reagents to deliver RNA into hematopoietic stem cells (HSCs) for cell and gene therapy applications.

DM IL LED Inverted Laboratory Microscope

With high-performance optics and ergonomic design, the Leica DM IL LED is ideal for cell culture, micromanipulation, documentation of immunostained specimens, and routine live cell examinations.

The Leica DM IL LED features a comprehensive set of contrast methods to monitor your specimen the way you need. High-quality Phase contrast, excellent modulation contrast and brilliant fluorescence are just one fingertip away. Robust stability, plenty of space to work with tools, long working distances to accommodate large culture flasks and a stable illumination without heat make work at the microscope easy and convenient.

For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) including in-vitro-fertilization (IVF).

Organ-Chip Kits For Reproducible Results

Emulate's kits provide the essential components needed to create functional, living organ models on the Zoë^® Culture Module.

Formulation Development

FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES

FORMULATION DEVELOPMENT APPLICATIONS & STUDIES

FORMULATION DEVELOPMENT PRODUCTS & SERVICES

FORMULATION DEVELOPMENT SOLUTIONS

PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS