Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![Strategies For API Solubility And Bioavailability Enhancement: Selecting Technologies And Excipients]( "Practical Formulation Strategies For Poorly Soluble APIs")
Practical Formulation Strategies For Poorly Soluble APIsPoor aqueous solubility now defines most drug candidates in development, making early screening and solid-state assessment essential to achieving reliable exposure and avoiding costly reformulation downstream.
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![The Art of Protein Expression-FutureFields]( "The Art Of Protein Expression: A Guide To Understanding Difficult-To-Express Proteins")
The Art Of Protein Expression: A Guide To Understanding Difficult-To-Express ProteinsProtein expression failures often result from misfolding, PTMs, assembly issues, insolubility, and toxicity. Understanding their interplay can improve yields.
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![GettyImages-2280454860-scientist-liver-organ-research]( "The Continuing Challenge Of Drug-Induced Liver Injury")
The Continuing Challenge Of Drug-Induced Liver InjuryRecent liver safety concerns highlight the limits of conventional preclinical testing. Human-relevant models could help researchers detect drug-induced liver injury earlier and reduce costly setbacks.
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![Smart Manufacturing facility-GettyImages-1938951579]( "Safety First: Considerations When Formulating High Potency Compounds")
Safety First: Considerations When Formulating High Potency CompoundsDeveloping highly potent APIs comes with unique challenges. Explore strategies for managing risk, protecting personnel, and advancing programs with confidence.
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![GettyImages-1585548490-modular-facility-laboratory-drug-development]( "Insights Into Evionnaz's new R&D Center")
Insights Into Evionnaz's new R&D CenterPharmaceutical innovation depends on speed and smarter decisions. Discover how advanced R&D technologies and real-time insights are helping accelerate development.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![GettyImages-1370147753-white-tablets-pill-bottle]( "Formulation And Process Challenges For A Needle-Shaped API")
Formulation And Process Challenges For A Needle-Shaped APIManaging challenging active pharmaceutical ingredient crystal structures and choosing dry granulation over wet granulation requires strategic processing choices.
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![From Sequence To Scale In Seven Months_Future Fields]( "From Sequence To Scale In Seven Months")
From Sequence To Scale In Seven MonthsAccelerate recombinant protein development from sequence to scale while maintaining stable expression, manufacturing efficiency, and critical quality attributes.
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![Protein that mutates in the development of cancer-GettyImages-1466537448]( "Characterizing Protein Stability By DSC")
Characterizing Protein Stability By DSCDiscover how differential scanning calorimetry quantifies the thermodynamic forces behind protein folding and stability, providing valuable insight for protein engineering and therapeutic formulation.
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![GettyImages-2202060913-protein-structure-blue-and-white-3d]( "Life Science Applications Of DSC")
Life Science Applications Of DSCLearn how Differential Scanning Calorimetry directly measures macromolecular stability, unfolding, and binding interactions, providing valuable thermodynamic insights for protein engineering.
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![GettyImages-1167352850-antibody-green]( "Streamline Antibody Analysis For Faster Protein Characterization")
Streamline Antibody Analysis For Faster Protein CharacterizationStrengthen your antibody characterization. Explore approaches for improving sizing accuracy, resolving heterogeneity, and generating reproducible data across demanding biopharmaceutical workflows.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
LMD 6 Laser Microdissection Microscope
Dissection Perfection
Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.
LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.
We move the laser, not the sample. And we use gravity for collection. That is why our LMD systems provide you with perfectly cut, contamination-free, analysis-ready dissectates.
The journey of a GLP-1 receptor agonist (GLP-1 RA) molecule is complex.
Custom microscopy workstations to meet your advanced imaging needs.
Measure heat flow, weight loss, dimension change, or mechanical properties as a function of temperature.
The systems can be provided in sterile, toxic or sterile toxic arrangements with the great advantage of being 100 % scalable.
Configurable, high-throughput widefield imaging solution for an incredible range of assays
Flexible, reliable control and bioreactor systems for laboratory applications
Thermo Scientific™ HyPerforma™ bioprocess control systems are designed to optimize your process from the laboratory bench to full cGMP manufacturing. Our innovative control platform combines a flexible operating system with scalable, modular hardware, novel single-use sensors, and state-of-the-art bioreactors for strategic and streamlined bioprocess control.
HyPerforma benchtop solutions offer robust management of both cell culture and fermentation processes. The open architecture provides process flexibility, and dedicated hardware control allows for expansion. Thermo Scientific™ TruBio™ software is designed to support easy process control and scaling.
FORMULATION DEVELOPMENT SOLUTIONS
- Cell Culture Media For Viral Vector Production
- Improve The Performance Of Your Biologic Formulations
- Increased Productivity Powered By An Automation Workstation
- Expediting Drug Discovery From Concept To Commercialization
- Preparative Chromatography System Intended For Method And Process Development
- A High-Purity Excipient Suitable For High-Risk Vaccine Applications
- Drive Your Performance Forward With The Expanded Family Of Efficient-Pro Feeds
- Simplify Your Linker-Payload Synthesis
- API Stability Combined With Rapid Disintegration
- A Technology-Driven CDMO Delivering Integrated End-To-End Services
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Contec Launches Sterile ReadySAT™ With PeridoxRTU® Sporicidal Wipes For Cleanrooms
- Upperton Unveils New Brand Identity Reflecting Evolution Into Specialist CDMO
- Hovione To Commission World's First ConsiGma® CDC Flex, Bringing Next-Generation Continuous Tableting To The U.S.
- Agilent Expands Oligonucleotide Manufacturing Capabilities With New Boulder Lab
- Flamma Acquires API Manufacturing Site In Padova, Italy
- Bayer Expanding U.S. Pharmaceutical Manufacturing Footprint With New Ohio Manufacturing Facility
- ROSS 600-Gallon ASME Pressure Vessel For High-Pressure Processing
- METTLER TOLEDO Expands Foreign Material Re-Inspection Services With New Dallas Facility
- Serán Bioscience Strengthens Spray Dry Capabilities With Growth Investment From Biospring Partners To Accelerate Commercial Expansion And Meet Surging Customer Demand
- Rottendorf Pharma Is CDMO Leadership Award Winner 2025