Formulation Development

Evaluating small and large molecule therapeutics within cellular environments is essential to understanding their efficacy, potency, and safety within a complex biological system.

Characterize Samples and Identify Unknown Components

Do you often need to identify unknown compounds from complex samples? ACD/MS Structure ID Suite offers a simple, replicable workflow for generating and narrowing down structural candidates.

• Deconvolute complex LC/MS and GC/MS data into individual component traces
• Search proprietary and commercial databases for spectral matches
• Search PubChem for accurate-mass and molecular-formula matches
• Narrow down candidate structures by retention time and fragment include/exclude lists

Analyzing GLP-1 receptor agonist (RA) drugs has become increasingly complex. Peptide structures, closely-related impurities, and rising demands for sensitivity, speed, and compliance are putting pressure on laboratories.

Rules-Based Fragment Prediction for Mass Spectrometry

ACD/MS Fragmenter helps you predict mass spectral fragmentation in seconds. Have more confidence in your compound IDs, learn about fragmentation mechanisms, and publish your results easily.

It’s as simple as this:

• Draw your compound
• Select the ionization polarity and fragmentation options
• View its fragmentation tree

Routine cell culture? Check!

For researchers who need consistent experimental outcomes, Mateo TL enables all lab members to check and document cell growth status conveniently and comfortably.

Measure confluency consistently, thereby increasing the confidence in the success of their downstream experiments.

Calculators & Predictors for LogP, LogD, pK_a, Aqueous Solubility, and more…

The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.

ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.

• Predict aqueous solubility,^* boiling point, logD,^* logP,^* pK_a,^* Sigma, and other molecular descriptors for organic compounds, from structure
• Evaluate the calculated results with sorting, plotting tools
• Assess the reliability of predicted physicochemical property values
• Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
• Train predictors with experimental data to better reflect novel chemical space
• Include custom models and in-house prediction algorithms

^*Models are trainable with experimental data

Curia’s expert scientists use advanced technology to produce and analyze high-quality recombinant proteins.

Designed for today’s assays and tomorrow’s breakthroughs—flexible detection that evolves with your science.

The SpectraMax® iD3s and iD5e Multi-Mode Microplate Readers deliver flexible, scalable solutions for absorbance, fluorescence, and luminescence assays—with advanced capabilities for evolving research needs. The iD3s reader offers a streamlined, affordable platform with a tunable monochromator and temperature control, while the iD5e reader adds enhanced detection modes including time-resolved fluorescence (TRF) and tunable fluorescence polarization (FP) and can be expanded to include TR-FRET, HTRF, BRET and western blot. Both readers support on board fluidics with optional dual injectors.