Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![Blood diagnostics, laboratory testing, disease biomarkers, medical technology-GettyImages-2218591456]( "From Biomarker Data To Proof Of Mechanism")
From Biomarker Data To Proof Of MechanismBiomarker values support mechanism only when the decision, analytical plan, and validation are designed as one chain, with expected direction of change and baseline noise defined before sampling.
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![trialkit-api-GettyImages-2223712653]( "Difficult-To-Purify And Difficult-To-Filter Small Molecules")
Difficult-To-Purify And Difficult-To-Filter Small MoleculesPoor filterability and stubborn impurities often trace back to the same molecular features, which changes how development teams approach scale-up for larger, structurally complex small molecules.
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![scientists working in laboratory-GettyImages-525440711]( "Choosing The Right CDMO For Substance Development And Manufacturing")
Choosing The Right CDMO For Substance Development And ManufacturingControlled substance programs demand licensing, closed-system custody, and inspection history well beyond GMP. Sponsors weighing partners must test technical depth against compliance infrastructure.
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![GettyImages-2184563761 molecules]( "Expert Q&A: Navigating Complexity In Modern Small Molecule Development")
Expert Q&A: Navigating Complexity In Modern Small Molecule DevelopmentSmall molecules are growing larger, more potent, and more structurally complex while timelines compress. That combination reshapes scale-up, outsourcing relationships, and the criteria for choosing a manufacturing partner.
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![capsule-development-GettyImages-2215837457]( "A Connected Approach To OSD Development")
A Connected Approach To OSD DevelopmentSee how an integrated OSD development strategy can identify risks early, strengthen process understanding and prepare products for scale-up, tech transfer and commercialization.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![partnership or agreement in the pharmaceutical industry-GettyImages-2173667078]( "From Early Development To Commercial Launch: An End-To-End Partnership")
From Early Development To Commercial Launch: An End-To-End PartnershipBringing a critical therapy to market takes early coordination. See how strategic planning helped accelerate an oncology therapy from clinical development to patients.
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![pharmacology, chemistry, micropipette, biotechnology, Liquid Chromatography-GettyImages-1494345439]( "Selecting The Right Chromatography Strategy")
Selecting The Right Chromatography StrategyDifficult small molecule purifications rarely yield to one technique. Modeling, fraction mapping, and preparative HPLC each solve a different problem, and the right choice depends on the molecule.
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![GettyImages-1052204504-crystallization]( "Optimizing Particle Properties For Difficult Small Molecules")
Optimizing Particle Properties For Difficult Small MoleculesCrystal morphology and unexpected solid-state intermediates often decide whether a difficult small molecule filters, dries, and scales. Thermodynamic stability may not be the right target.
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![science laboratory research, healthcare innovation, development, investigation-GettyImages-1751659695]( "Turning A \"Brick Dust\" Compound Into A Clinically Viable Oral Formulation")
Turning A "Brick Dust" Compound Into A Clinically Viable Oral FormulationAdvanced wet milling and particle stabilization improve solubility, enhance bioavailability, and support scalable manufacturing for complex oral drug development programs.
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![Drug R-D_GettyImages-1483266787]( "Creating A New Dosage Form From An Approved Drug For A New Rare Disease")
Creating A New Dosage Form From An Approved Drug For A New Rare DiseaseAdvancing approved drugs into new indications requires smart formulation, strong quality controls, and regulatory expertise to overcome challenges and accelerate patient access.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Preconfigured protocols and custom assay workflows simplify microplate data acquisition and analysis
SoftMax® Pro Software for Windows 10 is designed to provide the simplicity, flexibility and power required for advanced data analysis. It provides ready-to-run protocols, analysis algorithms, and 21 different curve fit options.
Curia was the first CRO to provide contract medicinal chemistry services to the pharmaceutical industry.
Enabling you to design vaccines without reliance on animal sources with our fermentation-produced squalene.
Gain human-relevant insights with patient-derived assay-ready organoids.
Designed for today’s assays and tomorrow’s breakthroughs—flexible detection that evolves with your science.
The SpectraMax® iD3s and iD5e Multi-Mode Microplate Readers deliver flexible, scalable solutions for absorbance, fluorescence, and luminescence assays—with advanced capabilities for evolving research needs. The iD3s reader offers a streamlined, affordable platform with a tunable monochromator and temperature control, while the iD5e reader adds enhanced detection modes including time-resolved fluorescence (TRF) and tunable fluorescence polarization (FP) and can be expanded to include TR-FRET, HTRF, BRET and western blot. Both readers support on board fluidics with optional dual injectors.
In the pharmaceutical industry, every capsule and tablet begins with a concept. Transforming that idea into a tangible product requires an expert manufacturing partner. Natoli stands out as a leader in pharmaceutical equipment and services, providing a comprehensive journey from formulation to full-scale production.
Patch-clamp amplifiers from, whole-cell, and two electrode recordings, single channels to large macroscopic recordings
The Axon Instruments® series of amplifiers provide best-in-class solutions for the entire range of patch-clamp experiments.
Ergonomic system microscope Leica DM1000 LED
The Leica DM1000 LED features long-life LED illumination that provides near daylight, bright illumination with constant color temperature and emits less heat.
The LED also eliminates the need for lamp changes, which saves time and money. Because of its low power consumption, the system is energy efficient. Users of the Leica DM1000 LED benefit from the system’s ability to uniquely adapt to every user.
It is ideal for all clinical laboratory applications, especially for cytology, haematology, and pathology. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).
FORMULATION DEVELOPMENT SOLUTIONS
- Steroids: Development And Manufacturing
- Enhance Dissolution Rate With A Single High Performance Excipient
- Early Development: Accelerating Molecules Through To Proof-Of-Concept
- Process Chemistry: Specialty Reagents And Custom Intermediates
- Improve The Performance Of Your Biologic Formulations
- Cell Culture Media For Viral Vector Production
- Drive Your Performance Forward With The Expanded Family Of Efficient-Pro Feeds
- ACQUITY Premier Analytical Solution
- Customizable Imaging Workstations
- CHO Residual DNA Quantitation
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Lonza Signs Agreement To Acquire US CDMO Network From Merck KGaA, Darmstadt, Germany, And Significantly Expands Its US Presence
- Bracco To Build New Injectable Drug Manufacturing Facility In North Carolina
- Lonza Further Expands Bioconjugation Manufacturing To Support Growing ADC Demand
- ROSS Portable High Shear Mixing System
- Ardena Launches Online Biomarker Catalogue: 228 Markers, One Quote Request
- Meissner Hosts Ribbon Cutting Ceremony For X-Ray Irradiation Services And Breaks Ground On Phase 2 Of Its Athens, Georgia, U.S.A. Campus
- Global Pharma Manufacturing Community Meets In Berlin For PHARMAP 2027
- LGM Pharma Acquires Sannova Analytical, Expanding cGMP Analytical And GLP Bioanalytical Services
- MVIC And Upperton Pharma Solutions Announce Strategic Collaboration
- All-In-One Solution For Continuous Microbial Monitoring Without Production Interruptions