Formulation Development

STELLARIS 8 FALCON FLIM Microscope

The contrast is clear. Lifetime imaging in an instant.

STELLARIS 8 FALCON (FAst Lifetime CONtrast) is the future of functional imaging. Harness the power of fluorescence lifetime to investigate cellular physiology and explore dynamics in living cells. STELLARIS 8 FALCON is a fully integrated solution for Fluorescence Lifetime Imaging (FLIM) and enables video-rate lifetime imaging acquisition for rapid kinetic studies in live cells.

STELLARIS 8 FALCON adds a new dimension of contrast to your imaging, opening the door to biosensing and tracking of interactions between proteins. FLIM information is now available for all modalities of the STELLARIS 8 system.

The systems can be provided in sterile, toxic or sterile toxic arrangements with the great advantage of being 100 % scalable.

Leica DM300

For slightly more advanced students in biology or 2-4 year college life science classrooms, the Leica DM300 compound microscope is compact, maintenance-free and easy to use to provide trouble free operation each day.

Equipped with a mechanical stage to accommodate two specimen slides and labelled Abbe condenser, the DM300 can be configured with rotatable monocular or binocular tubes for shared viewing and easy storage. Trinocular tube is also possible to go digital.

With 165 years of microscope design and manufacturing experience, the Leica DM300 student microscope provides students with the capabilities they need to study the finest details in all the Life Sciences.

In the pharmaceutical industry, every capsule and tablet begins with a concept. Transforming that idea into a tangible product requires an expert manufacturing partner. Natoli stands out as a leader in pharmaceutical equipment and services, providing a comprehensive journey from formulation to full-scale production.

Cell DIVE Multiplex Imaging Solution

What if every scientist could map normal and diseased tissue by cell type, biomarker profile, and specific features?

Cell DIVE is a precise, open multiplexing solution that lets your research dictate the level of automation required, which antibodies to use, how to build your antibody panel, and more.

Encoded stereo microscopes Leica M165 C​ - Total recall of your settings

Your goal: high-quality images that allow measurements and can be accurately repeated with minimal effort. The Leica coded stereo microscopes help you to pave the way to correct results.

• Coded microscopes consistently deliver calibrated and comparable images

• Reproduce images in moments with the Leica “Store and Recall” function

• Fully apochromatic corrected zoom optics deliver high quality images

• Customize the microscope system to your task with the exclusive range of accessories

Filterless readers provide consistent results with steady temperature regulation

The SpectraMax® ABS and ABS Plus absorbance microplate readers provide the flexibility, sensitivity, and convenience for a wide range of assays such as ELISAs, microbial growth, and protein quantitation. Both readers feature an 8-channel read head for fast reads and a subset feature, the temperature independent PathCheck sensor that automatically normalizes and ensures accurate absorbance values by detecting pipetting errors. Combined with a wide application base, industry-leading SoftMax® Pro Software and validation tools, these readers fit in every lab and every budget.

Calculators & Predictors for LogP, LogD, pK_a, Aqueous Solubility, and more…

The physicochemical properties of a molecule can help you better understand its likely behavior, support QSPR high-throughput screening (HTS) of libraries, and data-driven lead optimization.

ACD/PhysChem Suite is made up of a number of prediction modules. It provides high-quality, structure-based calculations of physicochemical properties.

• Predict aqueous solubility,^* boiling point, logD,^* logP,^* pK_a,^* Sigma, and other molecular descriptors for organic compounds, from structure
• Evaluate the calculated results with sorting, plotting tools
• Assess the reliability of predicted physicochemical property values
• Investigate quantitative structure-property relationships, structure modifications, and/or lead optimization for a target profile
• Train predictors with experimental data to better reflect novel chemical space
• Include custom models and in-house prediction algorithms

^*Models are trainable with experimental data