Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
-
![pharmaceutical factory equipment-GettyImages-499694183]( "Beyond PMI: Solvents As A Key To Sustainable Process Design")
Beyond PMI: Solvents As A Key To Sustainable Process DesignDiscover how data-driven solvent selection helps uncover sustainability opportunities, boost efficiency, and enable smarter process optimization decisions.
-
![Oligonucleotides-GettyImages-2234236209]( "How Data-Driven Development Is Transforming Phosphoramidites")
How Data-Driven Development Is Transforming PhosphoramiditesHigh-quality phosphoramidites are key to oligonucleotide therapies. Learn how data-driven optimization boosts purity, streamlines manufacturing, speeds scale-up, and supports commercialization.
-
![pharma-partners-GettyImages-2182052451]( "Three Keys To E&L Success: Study Design, Partner Selection, And Timing")
Three Keys To E&L Success: Study Design, Partner Selection, And TimingSuccessful E&L planning starts before testing begins. Aligning study design, partner expertise, and timing helps teams focus on the right risks, avoid surprises, and support stronger development.
-
![Strategies For API Solubility And Bioavailability Enhancement: Selecting Technologies And Excipients]( "Patented Process For Olopatadine HCl API Intermediates")
Patented Process For Olopatadine HCl API IntermediatesSee how this patented Wittig-based process for olopatadine HCl achieves Z/E isomer ratios up to 4:1, eliminating dangerous reagents like n-butyl lithium while cutting purification complexity.
-
![Reference_image_1]( "Platform Strategy For Improving Manufacturability And Efficacy In Bispecific Antibodies")
Platform Strategy For Improving Manufacturability And Efficacy In Bispecific AntibodiesNovel bispecific antibody engineering overcomes assembly and manufacturability challenges, enabling scalable production while preserving therapeutic function, stability, purity, and product quality.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
-
![Intestinal tract with digestive health-GettyImages-1985026058]( "Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling")
Predicting Food Effects In Oral Drug Delivery Using PBPK ModelingLearn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.
-
![GettyImages-163720603 tablet press, OSD]( "Compaction Simulation For Tablet Technology Transfer And Scale-Up")
Compaction Simulation For Tablet Technology Transfer And Scale-UpCompaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.
-
![GettyImages-1365580848-ubiquinol-softgel]( "Predicting Softgel Stability And Shelf Life Using Accelerated Modeling")
Predicting Softgel Stability And Shelf Life Using Accelerated ModelingPredict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.
-
![White Tablets-GettyImages-172969989]( "Predicting Drug-Loading Limits In Tablet Formulations")
Predicting Drug-Loading Limits In Tablet FormulationsLearn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
-
![GettyImages-498013412-laboratory-flask-water-solubility-dropper]( "Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies")
Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement StrategiesIn silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
The Ultimate NMR Software for Data Interpretation, Structure Characterization & Knowledge Management
ACD/NMR Workbook Suite is a comprehensive NMR software application. It features a full suite of advanced processing, analysis, and databasing functionalities for 1D and 2D NMR data from all major vendor formats.
Use NMR Workbook Suite to:
- Process and analyze NMR data easily with synchronized peak picking and assignment across datasets
- Reliably verify chemical structures
- Quantify and analyze mixtures
- Create comprehensive reports and publication-ready data
- Share, manage, and store live NMR spectra linked with structures
Leica DM750 Binocular
For a Student Friendly Classroom Environment
The Leica DM750 is the ideal microscope for the versatile needs of advanced college and university life science courses and professional training in medical, veterinary and dental schools.
Curia’s expert scientists use advanced technology to produce and analyze high-quality recombinant proteins.
Used Elizabeth Hata R&D tablet press, model EP200, B/D tooled with 10 station turret, 5 stations each B and D, 16 mm B, 22 mm D max tablet diameter, 17 mm B, 18 mm D max depth of fill, rated up to 6000 tablets/hour, with feed hoppers and feed frames, Machine #81, built 2011.
Power. Potential. Productivity.
STELLARIS 5 is a completely re-imagined confocal microscope platform.
STELLARIS confocal microscopes can be combined with all Leica modalities, including FLIM, STED, DLS, and CRS. With the STELLARIS confocal platform, we have re-imagined confocal microscopy to get you closer to the truth.
- Power to see more
- Potential to discover more
- Productivity to do more
S APO Greenough Stereo Microscope
Save up to 20% inspection and rework time*
Continuously improving production, keeping defect rates low, and fulfilling customer requests in order to stay competitive can be very challenging. Leica has developed the S9 stereo microscope series to help you cope with these challenges. With this generation of Greenough stereo microscopes operators will be able to reveal details faster as they spend less time having to adjust the microscope.
*compared to the standard industrial stereo microscope S6 from Leica
Quality control is a critical component for ensuring safety, efficacy, and consistency in the development and production of biologics. This comprehensive list of strategies, techniques, workflows, and best-in-class products for developing biopharmaceuticals can help you navigate the complexities of biologics and simplify the manufacturing process. Improve your quality control procedures and optimize your biologics production process with tools and expertise relied upon by researchers worldwide.
FORMULATION DEVELOPMENT SOLUTIONS
- Payload-Linker
- Eliminate Doubt With Chemistry Technical Services
- Explore A Wealth Of Applications In One Future-Ready System
- An Organ-Chip Platform That Generates Human-Relevant Data At Scale
- Oligonucleotide CDMO: From Preclinical To Commercial
- MaxPeak Premier Columns For Protein SEC Analysis
- Microcalorimetry: RS-DSC, DSC & ITC
- Small Molecule Drug Substance
- Be Unstoppable With Comprehensive Charge Variant Analysis
- Co-Crystal Prediction Service
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Amneal's Planned Sterile Facility Creates Opportunity For Aseptic Filling, Isolator, And Automation Suppliers
- Lonza Expands HPAPI Capacity In Visp, Further Supporting Its Position In Payload-Linker Manufacturing
- AustinPx Expands KinetiSol™ Technology Commercial Access Through Thermo Fisher Scientific Collaboration
- Recipharm Invests In U.S. Fill-Finish Infrastructure To Accelerate Biologics Development
- Four Myths About Embedded CMOs, Busted
- Avoiding Recalls: How To Ensure Sterility In Ophthalmic Products
- Veranova Appoints Dr. Bob Huang Vice President And General Manager Of West Deptford Site
- Leica Biosystems And CellCarta Expand Collaborative Companion Diagnostic Development Model To Accelerate Commercialization Globally
- Quotient Sciences Advances AI-Designed Drug Product Into Clinical Development
- ILC Dover Expands Life Sciences Presence With Water For Injection (WFI) And Custom Chemical Solutions