Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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The Importance Of Specificity In Preclinical Drug Development Models
It is crucial for models to not only detect toxic drugs but also to avoid erroneously identifying safe drugs as harmful. Learn about the importance of specificity in the early stages of drug development.
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Unraveling The Complexities Of Cancer Through Human-Relevant Models
The current paradigm in preclinical testing for cancer therapeutics is proving inadequate. Learn about Organ-on-a-Chip technology and how it is improving 3D cancer modeling.
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A More Human-Relevant Model To Advance AAV-Based Gene Therapies
Learn about a liver-chip that offers a more human-relevant way of testing viral vectors compared to conventional models and why it is a promising tool for advancing AAV gene therapy.
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Advancing Precision Medicine With Patient-On-A-Chip
Emulate and Cedars-Sinai Medical Center have partnered to develop a Patient-on-a-Chip program that combines their stem cell expertise and Organs-on-Chips technology to advance precision medicine.
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Organ-Chips And Animal Models: Sensitivity Explained
Learn about the significance of sensitivity in drug development and how researchers can improve their pipelines by employing more sensitive models.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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Advanced In Vitro Duodenal Model For Toxicity Assessment
Here, we review how an advanced in vitro model closely aligned with the human duodenum was utilized to evaluate the toxicity of indomethacin, a known gastrointestinal toxicant.
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Cytokine-Mediated Inflammation In A Relevant Preclinical Model
Learn about a novel preclinical model and how it enables the study of cytokine-mediated barrier inflammation mechanisms as well as the efficacy of anti-inflammatory therapeutics.
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The Application Of The Species-Specific Liver-Chip In Predicting Hepatoxicity
An evaluation of 150 drug candidates causing adverse events in humans revealed testing in rats and dogs predicted only 71% of toxicities in humans. Discover a solution to this translational challenge.
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Using Affinity Chromatography For The Purification Of Lentiviral Particles
This new new affinity chromatography resin offers an efficient and scalable purification method for lentiviral particles in combination with gentle elution conditions to retain viral infectivity.
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Analysis Of Drug-Excipient Incompatibility In Discovery And Formulation Development
We analyze drug-excipient incompatibility using a microcalorimeter system equipped with a multi-sample cell capable of simultaneously measuring highly sensitive heat flow data from up to three samples.
FORMULATION DEVELOPMENT SOLUTIONS
- ACQUITY Premier Analytical Solution
- European Center Of Excellence For Clinical Biologics
- Resin Offering High Productivity And Robust Processes
- Acceleratorâ„ Process Development Services
- Serum-Free, Xeno-Free Systems For Culture And Differentiation Of hMSCs
- Single-Use Chromatography System For Advanced Downstream Bioprocessing
- Mammalian Cell Culture: Process R&D Services
- Cryopreservation Medium For Various Tissue And Cell Types
- A CDMO With Oral Solid Dose And Sterile Injectable Expertise
- Single-Use Chromatography System For Scale-Up Flexibility
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- SMC Ltd. Announces Expansion Of Sterile Fill Finish Capabilities, Unveiling State-Of-The-Art Facility In North Carolina
- Natoli Engineering Welcomes Tablet Tooling Expert Todd Martin
- Syntegon Launches New SBM Essential Line Sterilizers: Standardization For Shorter Delivery Times
- Heuft And Nikka Densok To Exhibit Joint Solution At Achema For The Blow Fill Seal Proccess
- Elizabeth Hickman To Succeed Tim Scott As AustinPx CEO
- Ross Announces Rebuilt Double Planetary Mixers For High Viscosity Applications
- CoreRx To Acquire Societal CDMO In $130M Deal
- Spinnaker Life Sciences Strategy Consulting Emerges as a Leader Through Merger of Red Team Associates, Brooks Hill Partners, and Solstice Strategy Group
- Nelson Labs Announces Pharmaceutical Center Of Excellence To Serve Parenteral And Ophthalmic Drug Product Manufacturers
- Optima To Exhibit Filling, Isolator And Lyophilization Equipment Technologies At INTERPHEX 2024 Conference