Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
-
![GettyImages-2238837244-compliance-meeting-regulation-regulatory]( "Why CMC Continuity Is The Missing Link Between Development And Manufacturing")
Why CMC Continuity Is The Missing Link Between Development And ManufacturingDiscover why CMC continuity is the missing link between development and manufacturing, and how preserving connected product and process knowledge helps reduce handoff risk, accelerate tech transfer, and strengthen manufacturing readiness.
-
![paediatric-oral-dose-GettyImages-2251563567]( "Analytical Method Development For Paediatric Oral Dose Products")
Analytical Method Development For Paediatric Oral Dose ProductsThis article explores the key formulation and analytical challenges that pharmaceutical companies face when creating safe, effective, and age-appropriate treatments for paediatric populations.
-
![Solubility And Improved Patient Outcomes-GettyImages-2277363545]( "Solubility And Improved Patient Outcomes")
Solubility And Improved Patient OutcomesPoor solubility poses major development challenges. Innovative formulation technologies and careful excipient selection can improve bioavailability and product performance.
-
![GettyImages-1417391937-pharmaceutical-spray-drying-with-scientists]( "Overcoming The Obstacles Of Spray-Dried Dispersion Scale-Up")
Overcoming The Obstacles Of Spray-Dried Dispersion Scale-UpSDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.
-
![iStock-1248627316-chemistry-beaker-lab-science-experiment]( "Chemoenzymatic N-glycan Conjugation Of Native mAbs Provides Homogeneous, Efficacious ADCs")
Chemoenzymatic N-glycan Conjugation Of Native mAbs Provides Homogeneous, Efficacious ADCsA chemoenzymatic two-stage protocol enables DAR2 ADCs from native, non-engineered mAbs via glycan remodeling at Asn-297 and copper-free click chemistry, with in vivo efficacy outperforming a comparable marketed ADC.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
-
![Cell and Gene pharma manufacturing bioprocess GettyImages-1166528646]( "Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A Resins")
Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A ResinsProtein A chromatography intensification can increase productivity, but it may also affect process robustness. Explore key tradeoffs, operational challenges, and practical considerations.
-
![GettyImages-899692950-cleanroom-microscopes-scientists-analyze]( "Detect Low-Abundance GLP-1 Impurities With Greater Sensitivity")
Detect Low-Abundance GLP-1 Impurities With Greater SensitivityLow-level impurities can be difficult to resolve using conventional approaches. Discover how a Charged Surface 2.3 µm superficially porous Phenyl-Hexyl column enhances reversed-phase LC-MS analysis.
-
![GettyImages-1309780330-HPLC-lab-scientist-chromatography]( "Differentiate Challenging Site-Specific Isomeric Amino Acids")
Differentiate Challenging Site-Specific Isomeric Amino AcidsLearn how high-resolution ion mobility, pre-IMS fragmentation, and product ion analysis can resolve difficult peptide isomers and localize structural differences, supporting confident characterization.
-
![Female researcher analyzing scientific samples-GettyImages-2231025177]( "Increase Throughput For Intact Mass Confirmation And Impurity Screening")
Increase Throughput For Intact Mass Confirmation And Impurity ScreeningAccelerate intact mass analysis of GLP-1 analogues with automated purity calculations, sub-ppm mass accuracy, and impurity detection for consistent results in under one minute per sample.
-
![quality control, sterile pharmaceutical manufacturing facility-GettyImages-2277115553]( "Integrated QC As A Development Strategy: Reducing Late-Stage Analytical Risk")
Integrated QC As A Development Strategy: Reducing Late-Stage Analytical RiskLearn how early QC integration, proactive analytical risk management, and cross-functional collaboration can improve validation readiness, reduce development surprises, strengthen release testing predictability, and help protect critical clinical manufacturing timelines.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
Gain human-relevant insights with patient-derived assay-ready organoids.
Measure heat flow, weight loss, dimension change, or mechanical properties as a function of temperature.
Microscope Camera K3C
For Life Science and Industry Imaging Applications and Analysis
The K3C color and K3M monochrome cameras are your solutions for fast and reliable analytical tasks typically done for life science, industrial, and clinical applications. These cameras empower you to image a vast range of challenging samples with color-brightfield and fluorescence microscopy. Examples include fluorescently labeled and stained tissues and cells, particles for cleanliness analysis, steel, and forensic evidence.
MabSelect™ VL resin — protein L resin for affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
Decode 3D biology in real time*
The THUNDER Imager Model Organism allows fast and easy 3D exploration of whole organisms for developmental or molecular biology research. Thanks to THUNDER Live, your images reveal the finest structural details already in the live image. No hassle with out-of-focus blur while maintaining the capabilities and ease-of-use typical for Leica stereo microscopes.
A THUNDER Imager Model Organism is the optimal instrument for studying, e.g., Drosophila, C. elegans, zebrafish, plants, and mice. One device for screening, positioning, and imaging your specimen. Simplify your workflow and study model organisms from a large overview to the highest detail.
Uniquely Ergonomic System Microscope Leica DM1000
The ergonomically designed Leica DM1000 with adjustable features and easy-to-use controls adapts to every user to improve comfort and convenience while working at the microscope.
Featuring high-quality optical performance, the Leica DM1000 is ideal for all clinical laboratory applications, in particular cytology, haematology, and pathology. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).
Its advanced capabilities, including fluorescence, make it well suited also for complex tasks.
Used Shimadzu X-Ray Diffractometer, model XRD-6000, 220 volt, serial# Q30344800678 CZ
Custom microscopy workstations to meet your advanced imaging needs.
FORMULATION DEVELOPMENT SOLUTIONS
- API Stability Combined With Rapid Disintegration
- Sterile Drug Product
- A High-Purity Excipient Suitable For High-Risk Vaccine Applications
- A Streamlined Approach For The APC Labeling/Conjugation Of Antibodies
- Comprehensive ADC And Bioconjugation Services For Targeted Therapies
- Molecule To Cure. Fast.
- A Viral Safety Solution Designed To Provide Retention Assurance And Productivity
- High-Quality Filter Housings For Sanitary Applications
- Process Liquid Preparation Services
- An Organ-Chip Platform That Generates Human-Relevant Data At Scale
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- Jubilant HollisterStier Announces First FDA Commercial Product Approval For Sterile Fill-Finish Line 3
- Ardena To Attend CPHI Worldwide Milan 2026, Launching Charity Step Challenge "From Molecules To Miles"
- AST Names Industry Veteran Jon Lenihan As Chief Commercial Officer
- JHS And Altoura Selected For BioTools Innovator VANGUARD Level Up-XR Program
- Syntegon Launches New Pilot Scale Tablet Coater For Small Batches
- Cambrex High Point Completes FDA, PMDA And TGA PreApproval Inspections, Advancing Commercial Manufacturing Capabilities
- CleanSpace Names Pharma Industry Veteran Will Knapp Midwest Sales Director
- METTLER TOLEDO Introduces LightningBuild Program For Four-Week Delivery
- Eurofins CDMO Alphora Expands Kilolab And High Potency Development And Manufacturing Capabilities
- Ypsomed Opens Production Site In China