Formulation Development
FORMULATION DEVELOPMENT WHITE PAPERS & ARTICLES
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![cdmo-solid-dose-GettyImages-1432665138]( "How To Achieve Late-Phase Success In Complex OSD Development")
How To Achieve Late-Phase Success In Complex OSD DevelopmentLate-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.
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![GettyImages-1194851415-OSD-oral-solid-tablet-pill-capsule]( "Reducing Uncertainty In Early Oral Drug Development")
Reducing Uncertainty In Early Oral Drug DevelopmentFive recurring decision points in early oral solid dose development carry outsized downstream consequences. AI/ML-driven predictive modeling is reframing how teams manage those decisions under API and timeline constraints.
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![GettyImages-2270210340-lipid-nanoparticle-delivery-system]( "Lipid Formulation Development: Why Softgels Are The Technology Of Choice")
Lipid Formulation Development: Why Softgels Are The Technology Of ChoiceLow bioavailability affects roughly 80% of APIs, yet many drug developers default to standard OSD forms. This paper examines why softgels deserve earlier consideration in formulation strategy.
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![GettyImages-950086574-oral-solid-OSD-pill-tablet-capsule-development]( "5 Hidden Risks In Early-Phase OSD Formulation Development")
5 Hidden Risks In Early-Phase OSD Formulation DevelopmentEarly formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.
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![GettyImages-1370967510 hot cold]( "Overview Of Hot Melt Extrusion And Its Pharmaceutical Applications")
Overview Of Hot Melt Extrusion And Its Pharmaceutical ApplicationsMore than 40% of NCEs face aqueous solubility challenges. Here, we examine how hot melt extrusion addresses solubility, modified release, abuse deterrence, and scale-up across pharmaceutical development.
FORMULATION DEVELOPMENT APPLICATIONS & STUDIES
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![GettyImages-528971880 chromatography]( "Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A Resins")
Don't Intensify Blindly: Preventing Fouling And Restoring Performance With Targeted Cleaning Of Protein A ResinsProtein A chromatography intensification can increase productivity, but it may also affect process robustness. Explore key tradeoffs, operational challenges, and practical considerations.
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![GettyImages-899692950-cleanroom-microscopes-scientists-analyze]( "Detect Low-Abundance GLP-1 Impurities With Greater Sensitivity")
Detect Low-Abundance GLP-1 Impurities With Greater SensitivityLow-level impurities can be difficult to resolve using conventional approaches. Discover how a Charged Surface 2.3 µm superficially porous Phenyl-Hexyl column enhances reversed-phase LC-MS analysis.
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![GettyImages-1309780330-HPLC-lab-scientist-chromatography]( "Differentiate Challenging Site-Specific Isomeric Amino Acids")
Differentiate Challenging Site-Specific Isomeric Amino AcidsLearn how high-resolution ion mobility, pre-IMS fragmentation, and product ion analysis can resolve difficult peptide isomers and localize structural differences, supporting confident characterization.
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![Female researcher analyzing scientific samples-GettyImages-2231025177]( "Increase Throughput For Intact Mass Confirmation And Impurity Screening")
Increase Throughput For Intact Mass Confirmation And Impurity ScreeningAccelerate intact mass analysis of GLP-1 analogues with automated purity calculations, sub-ppm mass accuracy, and impurity detection for consistent results in under one minute per sample.
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![quality control, sterile pharmaceutical manufacturing facility-GettyImages-2277115553]( "Integrated QC As A Development Strategy: Reducing Late-Stage Analytical Risk")
Integrated QC As A Development Strategy: Reducing Late-Stage Analytical RiskLearn how early QC integration, proactive analytical risk management, and cross-functional collaboration can improve validation readiness, reduce development surprises, strengthen release testing predictability, and help protect critical clinical manufacturing timelines.
FORMULATION DEVELOPMENT PRODUCTS & SERVICES
- Enables sample recovery
- Avoids dilution effects
- Analyzes samples in a matrix-free environment
- Has minimal buffer constraints
Leica M80 Routine Stereo Microscopes
Easily inspect, screen, observe or document. Handle your daily inspection or documentation, work confidently, and stay flexible in times of change. The modular stereo microscopes of the M series from Leica are the right choice for an abundant variety of tasks in life sciences and industrial applications.
The M50, M60, and M80 allow operators to see a large sample overview, work comfortably under the microscope, and capture images of important details easily.
Leica DM500 Binocular
Supports a Student Friendly Classroom Environment For Life Science Courses
The Leica DM500 microscope with “plug and play” capability is the ideal tool to make teaching entry-level college and university Life Science courses easy and fun for the instructor and the student.
Student-friendly features such as the pre-focused, pre-centered condenser and the EZTube™ preset diopter, which prevent incorrect adjustments, provide more time for hands-on teaching.
EZStore™ design with integrated handle and cord wrap allows easy carrying, easy lifting and protection against microscope component damage.
Designed for today’s assays and tomorrow’s breakthroughs—flexible detection that evolves with your science.
The SpectraMax® iD3s and iD5e Multi-Mode Microplate Readers deliver flexible, scalable solutions for absorbance, fluorescence, and luminescence assays—with advanced capabilities for evolving research needs. The iD3s reader offers a streamlined, affordable platform with a tunable monochromator and temperature control, while the iD5e reader adds enhanced detection modes including time-resolved fluorescence (TRF) and tunable fluorescence polarization (FP) and can be expanded to include TR-FRET, HTRF, BRET and western blot. Both readers support on board fluidics with optional dual injectors.
The journey of a GLP-1 receptor agonist (GLP-1 RA) molecule is complex.
Leica M60 Routine Stereo Microscopes
Easily inspect, screen, observe or document. Handle your daily inspection or documentation, work confidently, and stay flexible in times of change. The modular stereo microscopes of the M series from Leica are the right choice for an abundant variety of tasks in life sciences and industrial applications.
The M50, M60, and M80 allow operators to see a large sample overview, work comfortably under the microscope, and capture images of important details easily.
Sterility is key for high-risk applications such as injectables, parenteral formulations, ophthalmic and peritoneal dialysis solutions, and many more.
Accelerate your gene therapy manufacturing with the Xcellerex™ X-platform – a next-generation single-use bioreactor system designed for viral vector workflows.
FORMULATION DEVELOPMENT SOLUTIONS
- A Viral Safety Solution Designed To Provide Retention Assurance And Productivity
- High-Content Screening System
- Preparative Chromatography System Intended For Method And Process Development
- An Alternative Suitable For High-Risk Applications
- Solid Form Services
- Culture Module That Sustains The Life Of Cells
- Small Molecule Drug Substance
- Simplify Your Linker-Payload Synthesis
- Eliminate Doubt With Chemistry Technical Services
- Adare Pharma Solutions (APS) Orbis Overview
PHARMACEUTICAL AND FORMULATION DEVELOPMENT NEWS
- AST Names Industry Veteran Jon Lenihan As Chief Commercial Officer
- JHS And Altoura Selected For BioTools Innovator VANGUARD Level Up-XR Program
- Syntegon Launches New Pilot Scale Tablet Coater For Small Batches
- Cambrex High Point Completes FDA, PMDA And TGA PreApproval Inspections, Advancing Commercial Manufacturing Capabilities
- CleanSpace Names Pharma Industry Veteran Will Knapp Midwest Sales Director
- METTLER TOLEDO Introduces LightningBuild Program For Four-Week Delivery
- Eurofins CDMO Alphora Expands Kilolab And High Potency Development And Manufacturing Capabilities
- Ypsomed Opens Production Site In China
- Ypsomed Launches YpsoLoop As The First Autoinjector Platform Designed For Circularity
- Ypsomed Expands Offering For Clinical Studies